In the book, "Me Before You" Lou Clark gets a tattoo of a bumblebee. Emilia Clarke's first tattoo was also a bumblebee on her finger which she got after wrapping the film.
In the week following the release of the trailer for the film, the book went from #141 to #3 on USA TODAY's Best-Selling Books List.
Filming of the castle-town exterior scenes took place in Pembrokeshire, Wales over five days in May 2015. The tranquil town saw road closures and an influx of fans hoping to catch a glimpse but disruption was kept to a minimum. The interior scenes were all shot later at Pinewood Studios.