Entry
Name
Flecainide acetate (JP18/USP); Tambocor (TN)
Product
Generic
FLECAINIDE ACETATE (A-S Medication Solutions) ,
FLECAINIDE ACETATE (A-S Medication Solutions) ,
FLECAINIDE ACETATE (A-S Medication Solutions) ,
FLECAINIDE ACETATE (A-S Medication Solutions) ,
FLECAINIDE ACETATE (A-S Medication Solutions) ,
FLECAINIDE ACETATE (ANI Pharmaceuticals) ,
FLECAINIDE ACETATE (Amneal Pharmaceuticals LLC) ,
FLECAINIDE ACETATE (Amneal Pharmaceuticals of New York LLC) ,
FLECAINIDE ACETATE (Aurobindo Pharma Limited) ,
FLECAINIDE ACETATE (AvPAK) ,
FLECAINIDE ACETATE (Bayshore Pharmaceuticals LLC) ,
FLECAINIDE ACETATE (Bryant Ranch Prepack) ,
FLECAINIDE ACETATE (Bryant Ranch Prepack) ,
FLECAINIDE ACETATE (Bryant Ranch Prepack) ,
FLECAINIDE ACETATE (Bryant Ranch Prepack) ,
FLECAINIDE ACETATE (Bryant Ranch Prepack) ,
FLECAINIDE ACETATE (Bryant Ranch Prepack) ,
FLECAINIDE ACETATE (Bryant Ranch Prepack) ,
FLECAINIDE ACETATE (Bryant Ranch Prepack) ,
FLECAINIDE ACETATE (Bryant Ranch Prepack) ,
FLECAINIDE ACETATE (Bryant Ranch Prepack) ,
FLECAINIDE ACETATE (Bryant Ranch Prepack) ,
FLECAINIDE ACETATE (Chartwell RX) ,
FLECAINIDE ACETATE (Epic Pharma) ,
FLECAINIDE ACETATE (Golden State Medical Supply) ,
FLECAINIDE ACETATE (Hikma Pharmaceuticals USA) ,
FLECAINIDE ACETATE (PD-Rx Pharmaceuticals) ,
FLECAINIDE ACETATE (PD-Rx Pharmaceuticals) ,
FLECAINIDE ACETATE (PD-Rx Pharmaceuticals) ,
FLECAINIDE ACETATE (Rising Pharma Holdings)
Formula
C17H20F6N2O3. C2H4O2
Exact mass
474.1589
Mol weight
474.39
Structure
Mol file KCF file DB search
Simcomp
Neighbor
Class
Cardiovascular agent
DG01653 Antiarrhythmics
DG01652 Class I antiarrhythmic agent
DG01650 Class Ic antiarrhythmic agent
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
Remark
Therapeutic category: 2129
Product (DG00201): D00638<JP /US>
Efficacy
Antiarrhythmic, Sodium channel blocker
Disease
Atrial fibrillation/flutter [DS:
H00731 ]
Target
Pathway
hsa04261 Adrenergic signaling in cardiomyocytes
Metabolism
Enzyme: CYP2D6 [HSA:
1565 ]
Interaction
DDI search
Structure map
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303 ]
C CARDIOVASCULAR SYSTEM
C01 CARDIAC THERAPY
C01B ANTIARRHYTHMICS, CLASS I AND III
C01BC Antiarrhythmics, class Ic
C01BC04 Flecainide
D00638 Flecainide acetate (JP18/USP) <JP/US>
USP drug classification [BR:br08302 ]
Cardiovascular Agents
Antiarrhythmics
Vaughn Williams-Class I
Flecainide
D00638 Flecainide acetate (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301 ]
2 Agents affecting individual organs
21 Cardiovascular agents
212 Antiarrhythmic agents
2129 Others
D00638 Flecainide acetate (JP18/USP)
Drug groups [BR:br08330 ]
Cardiovascular agent
DG01653 Antiarrhythmics
DG01652 Class I antiarrhythmic agent
DG01650 Class Ic antiarrhythmic agent
DG00201 Flecainide
D00638 Flecainide acetate
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
DG00201 Flecainide
D00638 Flecainide acetate
Drug classes [BR:br08332 ]
Cardiovascular agent
DG01653 Antiarrhythmics
D00638 Flecainide acetate
Target-based classification of drugs [BR:br08310 ]
Ion channels
Voltage-gated ion channels
Sodium channels
SCN1A
D00638 Flecainide acetate (JP18/USP) <JP/US>
SCN2A
D00638 Flecainide acetate (JP18/USP) <JP/US>
SCN3A
D00638 Flecainide acetate (JP18/USP) <JP/US>
SCN4A
D00638 Flecainide acetate (JP18/USP) <JP/US>
SCN5A
D00638 Flecainide acetate (JP18/USP) <JP/US>
SCN8A
D00638 Flecainide acetate (JP18/USP) <JP/US>
SCN9A
D00638 Flecainide acetate (JP18/USP) <JP/US>
SCN10A
D00638 Flecainide acetate (JP18/USP) <JP/US>
SCN11A
D00638 Flecainide acetate (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311 ]
Chemicals
D00638 Flecainide acetate
D00638 Flecainide acetate
Drug metabolizing enzymes and transporters [br08309.html ]
Drug metabolizing enzymes
D00638
Drug groups [BR:br08330 ]
Cardiovascular agent
DG01653 Antiarrhythmics
DG01652 Class I antiarrhythmic agent
DG01650 Class Ic antiarrhythmic agent
DG00201 Flecainide
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
DG00201 Flecainide
BRITE hierarchy
Other DBs
LinkDB
All DBs
KCF data
Show ATOM 32
1 C1x C 3.7100 -14.3500
2 C1x C 3.7100 -15.7500
3 N1x N 4.9224 -16.4500
4 C1y C 6.1349 -15.7500
5 C1x C 6.1349 -14.3500
6 C1x C 4.9224 -13.6500
7 C1b C 7.3660 -16.4610
8 N1b N 8.5712 -15.7653
9 C5a C 9.7535 -16.4481
10 C8y C 10.9475 -15.7588
11 O5a O 9.7535 -17.8498
12 C8y C 12.1354 -16.4448
13 C8x C 13.3479 -15.7449
14 C8x C 13.3480 -14.3449
15 C8y C 12.1601 -13.6589
16 C8x C 10.9476 -14.3588
17 O2a O 12.1601 -12.2501
18 C1b C 13.3874 -11.5414
19 C1d C 14.5904 -12.2360
20 X F 15.8028 -12.9360
21 X F 13.8771 -13.4722
22 X F 15.2764 -11.0472
23 O2a O 12.1354 -17.8498
24 C1b C 13.3288 -18.5389
25 C1d C 14.5148 -17.8542
26 X F 15.7273 -17.1542
27 X F 15.2066 -19.0527
28 X F 13.8071 -16.6279
29 C6a C 19.2500 -15.3300
30 C1a C 20.4639 -16.0327
31 O6a O 18.0419 -16.0327
32 O6a O 19.2500 -13.9303
BOND 32
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 9 11 2
12 10 12 2
13 12 13 1
14 13 14 2
15 14 15 1
16 15 16 2
17 10 16 1
18 15 17 1
19 17 18 1
20 18 19 1
21 19 20 1
22 19 21 1
23 19 22 1
24 12 23 1
25 23 24 1
26 24 25 1
27 25 26 1
28 25 27 1
29 25 28 1
30 29 30 1
31 29 31 1
32 29 32 2