| Entry |
|
|---|
| Name |
Promazine hydrochloride (USP);
Sparine (TN) |
|---|
| Formula |
C17H20N2S. HCl
|
|---|
| Exact mass |
320.1114
|
|---|
| Mol weight |
320.88
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG03200 Antipsychotic agent
DG01905 Phenothiazine antipsychotics
|
|---|
| Remark |
|
|---|
| Efficacy |
Antipsychotic, Dopamine D2 receptor antagonist |
|---|
| Comment |
Phenothiazine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07029 | Antipsychotics - phenothiazines |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05A ANTIPSYCHOTICS
N05AA Phenothiazines with aliphatic side-chain
N05AA03 Promazine
D00797 Promazine hydrochloride (USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00869 Promazine
D00797 Promazine hydrochloride
DG03200 Antipsychotic agent
DG01905 Phenothiazine antipsychotics
DG00869 Promazine
D00797 Promazine hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D00797 Promazine hydrochloride (USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00869 Promazine
DG03200 Antipsychotic agent
DG01905 Phenothiazine antipsychotics
DG00869 Promazine
|
|---|
| Other DBs |
|
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| LinkDB |
|
|---|
| KCF data |
ATOM 21
1 X Cl 36.9353 -17.9239
2 C8x C 26.7400 -17.2200
3 C8x C 26.7400 -18.6200
4 C8x C 27.9524 -19.3200
5 C8y C 29.1649 -18.6200
6 C8y C 29.1649 -17.2200
7 C8x C 27.9524 -16.5200
8 S2x S 30.3773 -19.3200
9 C8y C 31.5897 -18.6200
10 C8y C 31.5897 -17.2200
11 N4y N 30.3773 -16.5200
12 C8x C 32.8022 -19.3200
13 C8x C 34.0146 -18.6200
14 C8x C 34.0146 -17.2200
15 C8x C 32.8022 -16.5200
16 C1b C 30.3773 -15.1200
17 C1b C 31.5918 -14.4188
18 C1b C 32.7883 -15.1098
19 N1c N 33.9751 -14.4246
20 C1a C 35.1666 -15.1128
21 C1a C 33.9753 -13.0202
BOND 22
1 2 3 2
2 3 4 1
3 4 5 2
4 5 6 1
5 6 7 2
6 2 7 1
7 5 8 1
8 8 9 1
9 9 10 1
10 10 11 1
11 6 11 1
12 9 12 2
13 12 13 1
14 13 14 2
15 14 15 1
16 10 15 2
17 11 16 1
18 16 17 1
19 17 18 1
20 18 19 1
21 19 20 1
22 19 21 1
|
|---|
