| Entry |
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| Name |
Isoproterenol sulfate (USP);
Isoprenaline sulfate (JAN);
Luf-Iso (TN);
Medihaler-Iso (TN) |
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| Formula |
(C11H17NO3)2. H2SO4. 2H2O
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| Exact mass |
556.2302
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| Mol weight |
556.63
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| Structure |
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| Simcomp |
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| Class |
Cardiovascular agent
DG01703 Cardiotonic
DG01699 Catecholamine cardiotonic
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01951 Catecholamine adrenergic receptor agonist
Metabolizing enzyme substrate
DG01592 COMT substrate
|
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| Remark |
| Product (DG00211): | D01390<JP/US> D02150<JP> |
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| Efficacy |
Bronchodilator, beta-Adrenergic receptor agonist |
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| Comment |
Catecholamine derivative
Component of Stmerin-D (TN)
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
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| Metabolism |
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| Interaction |
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| Structure map |
| map07214 | beta-Adrenergic receptor agonists/antagonists |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C01 CARDIAC THERAPY
C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
C01CA Adrenergic and dopaminergic agents
C01CA02 Isoprenaline
D02066 Isoproterenol sulfate (USP)
R RESPIRATORY SYSTEM
R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
R03A ADRENERGICS, INHALANTS
R03AB Non-selective beta-adrenoreceptor agonists
R03AB02 Isoprenaline
D02066 Isoproterenol sulfate (USP)
R03C ADRENERGICS FOR SYSTEMIC USE
R03CB Non-selective beta-adrenoreceptor agonists
R03CB01 Isoprenaline
D02066 Isoproterenol sulfate (USP)
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01699 Catecholamine cardiotonic
DG00211 Isoprenaline
D02066 Isoproterenol sulfate
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG00211 Isoprenaline
D02066 Isoproterenol sulfate
DG01951 Catecholamine adrenergic receptor agonist
DG00211 Isoprenaline
D02066 Isoproterenol sulfate
Metabolizing enzyme substrate
DG01592 COMT substrate
DG00211 Isoprenaline
D02066 Isoproterenol sulfate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB
D02066 Isoproterenol sulfate (USP)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D02066
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01699 Catecholamine cardiotonic
DG00211 Isoprenaline
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG00211 Isoprenaline
DG01951 Catecholamine adrenergic receptor agonist
DG00211 Isoprenaline
Metabolizing enzyme substrate
DG01592 COMT substrate
DG00211 Isoprenaline
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 37
1 S4a S 30.7719 -15.7400
2 O1d O 30.8348 -14.3399
3 O1d O 30.8348 -17.1400
4 O1d O 32.1719 -15.7400
5 O1d O 29.3719 -15.7400
6 O0 O 36.8252 -15.6939
7 C8y C 18.4800 -16.2400
8 C8x C 17.2900 -15.4700
9 C8x C 18.4800 -17.6400
10 C8y C 16.1000 -16.1700
11 C8x C 17.2200 -18.2700
12 C8y C 16.1000 -17.5000
13 O1a O 14.9100 -15.4000
14 O1a O 14.9100 -18.2000
15 C1c C 19.7400 -15.5400
16 C1b C 20.9300 -16.2400
17 N1b N 22.1200 -15.5400
18 C1c C 23.3800 -16.2400
19 C1a C 24.5700 -15.5400
20 O1a O 19.7400 -14.1400
21 C1a C 23.3800 -17.6400
22 O0 O 36.8252 -15.6939
23 C8y C 18.4800 -16.2400
24 C8x C 17.2900 -15.4700
25 C8y C 16.1000 -16.1700
26 C8y C 16.1000 -17.5000
27 O1a O 14.9100 -18.2000
28 C8x C 17.2200 -18.2700
29 C8x C 18.4800 -17.6400
30 O1a O 14.9100 -15.4000
31 C1c C 19.7400 -15.5400
32 C1b C 20.9300 -16.2400
33 N1b N 22.1200 -15.5400
34 C1c C 23.3800 -16.2400
35 C1a C 24.5700 -15.5400
36 C1a C 23.3800 -17.6400
37 O1a O 19.7400 -14.1400
BOND 34
1 1 3 2
2 1 4 1
3 1 5 1
4 1 2 2
5 7 8 1
6 7 9 2
7 8 10 2
8 9 11 1
9 10 12 1
10 10 13 1
11 12 14 1
12 11 12 2
13 7 15 1
14 15 16 1
15 16 17 1
16 17 18 1
17 18 19 1
18 15 20 1
19 18 21 1
20 23 24 1
21 23 29 2
22 24 25 2
23 29 28 1
24 25 26 1
25 25 30 1
26 26 27 1
27 28 26 2
28 23 31 1
29 31 32 1
30 32 33 1
31 33 34 1
32 34 35 1
33 31 37 1
34 34 36 1
BRACKET 1 35.0000 -16.3800 35.0000 -14.8400
1 37.2400 -14.8400 37.2400 -16.3800
1 2
ORIGINAL 1 6
REPEAT 1 22
2 13.6500 -19.4600 13.6500 -12.1800
2 26.3200 -12.1800 26.3200 -19.4600
2 2
ORIGINAL 2 7 8 10 12 14 11 9 13 15 16 17 18 19 21 20
REPEAT 2 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37
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