Entry |
|
Name |
Methamphetamine hydrochloride (JP18/USP); Desoxyn (TN) |
Product |
|
Generic |
|
Formula |
C10H15N. HCl
|
Exact mass |
185.0971
|
Mol weight |
185.69
|
Structure |
|
Simcomp |
|
Class |
Neuropsychiatric agent
DG01971 Agents for narcolepsy
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
|
Remark |
Therapeutic category: | 1151 |
Product (DG00968): | D02242<JP/US> |
|
Efficacy |
Psychostimulant, Stimulant (central) |
Disease |
Attention deficit disorder with hyperactivity [DS: H01895] |
Target |
|
Pathway |
|
Metabolism |
Enzyme: CYP2D6 [HSA: 1565]
|
Interaction |
|
Structure map |
map07234 | Neurotransmitter transporter inhibitors |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N06 PSYCHOANALEPTICS
N06B PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
N06BA Centrally acting sympathomimetics
N06BA03 Metamfetamine
D02242 Methamphetamine hydrochloride (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
Central Nervous System Agents
Attention Deficit Hyperactivity Disorder Agents, Amphetamines
Methamphetamine
D02242 Methamphetamine hydrochloride (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
115 Stimulants
1151 Amphetamines
D02242 Methamphetamine hydrochloride (JP18/USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01971 Agents for narcolepsy
DG00968 Metamfetamine
D02242 Methamphetamine hydrochloride
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
DG00968 Metamfetamine
D02242 Methamphetamine hydrochloride
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC6
SLC6A2 (NAT1)
D02242 Methamphetamine hydrochloride (JP18/USP) <JP/US>
SLC6A3 (DAT1)
D02242 Methamphetamine hydrochloride (JP18/USP) <JP/US>
SLC6A4 (HTT)
D02242 Methamphetamine hydrochloride (JP18/USP) <JP/US>
SLC18
SLC18A1 (VMAT1)
D02242 Methamphetamine hydrochloride (JP18/USP) <JP/US>
SLC18A2 (VMAT2)
D02242 Methamphetamine hydrochloride (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D02242 Methamphetamine hydrochloride
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D02242
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01971 Agents for narcolepsy
DG00968 Metamfetamine
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
DG00968 Metamfetamine
|
Other DBs |
|
LinkDB |
|
KCF data |
ATOM 12
1 C8y C 15.8200 -15.6100
2 C1b C 17.0100 -14.9100
3 C8x C 14.5600 -14.9100
4 C8x C 15.8200 -17.0100
5 C1c C 18.2000 -15.6100
6 C8x C 13.3700 -15.6100
7 C8x C 14.5600 -17.7100
8 N1b N 19.4600 -14.9100
9 C1a C 18.2000 -17.0100
10 C8x C 13.3700 -17.0100
11 C1a C 20.6500 -15.6100
12 X Cl 23.8700 -16.3800
BOND 11
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 1
5 3 6 1
6 4 7 2
7 5 8 1
8 5 9 1 #Up
9 6 10 2
10 8 11 1
11 7 10 1
|