| Entry |
|
|---|
| Name |
Fiduxosin hydrochloride (USAN) |
|---|
| Formula |
C30H29N5O4S. HCl
|
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| Exact mass |
591.1707
|
|---|
| Mol weight |
592.11
|
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| Structure |
|
|---|
| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01457 alpha1-Adrenergic receptor antagonist
|
|---|
| Efficacy |
Antidysuria, alpha1-Adrenergic receptor antagonist |
|---|
| Comment |
Treatment of benign prostatic hyperplasia
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04270 | Vascular smooth muscle contraction |
|
|---|
| Interaction |
|
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| Brite |
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01457 alpha1-Adrenergic receptor antagonist
D04184 Fiduxosin hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA1A
D04184 Fiduxosin hydrochloride (USAN)
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 41
1 C8x C 5.3703 -2.9865
2 C8y C 5.3703 -4.3849
3 N5x N 6.5589 -5.0840
4 C8y C 7.8173 -4.3849
5 C8y C 7.8173 -2.9865
6 N5x N 6.5589 -2.2874
7 C8y C 9.1458 -4.8043
8 C8y C 9.9148 -3.6857
9 S2x S 9.1458 -2.5670
10 C8y C 11.3132 -3.6857
11 N4y N 12.0124 -4.8743
12 C8y C 11.3132 -6.0629
13 N4x N 9.9148 -6.0629
14 C8y C 4.1588 -5.0778
15 C8x C 2.9424 -4.3687
16 C8x C 1.7270 -5.0636
17 C8x C 1.7211 -6.4636
18 C8x C 2.9376 -7.1727
19 C8x C 4.1529 -6.4778
20 O5x O 12.0044 -2.4777
21 O5x O 12.0263 -7.3102
22 C1b C 13.4124 -4.8743
23 C1b C 14.1302 -6.1181
24 C1b C 15.5397 -6.1185
25 C1b C 16.2271 -7.3098
26 N1y N 17.6397 -7.3104
27 C1x C 18.4479 -8.4234
28 C1y C 19.7562 -7.9986
29 C1y C 19.7565 -6.6231
30 C1x C 18.4484 -6.1978
31 C1x C 20.9684 -8.6988
32 O2x O 22.1810 -7.9991
33 C8y C 22.1813 -6.6236
34 C8y C 20.9690 -5.9234
35 C8x C 23.3939 -5.9239
36 C8x C 23.3942 -4.5239
37 C8x C 22.1819 -3.8236
38 C8y C 20.9693 -4.5234
39 O2a O 19.7915 -3.8433
40 C1a C 18.5901 -4.5369
41 X Cl 7.2800 -8.0500
BOND 46
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 2
9 8 9 1
10 5 9 1
11 8 10 1
12 10 11 1
13 11 12 1
14 12 13 1
15 13 7 1
16 2 14 1
17 14 15 2
18 15 16 1
19 16 17 2
20 17 18 1
21 18 19 2
22 14 19 1
23 10 20 2
24 12 21 2
25 11 22 1
26 22 23 1
27 23 24 1
28 24 25 1
29 25 26 1
30 26 27 1
31 27 28 1
32 28 29 1
33 29 30 1
34 26 30 1
35 28 31 1
36 31 32 1
37 32 33 1
38 33 34 1
39 29 34 1
40 33 35 2
41 35 36 1
42 36 37 2
43 37 38 1
44 34 38 2
45 38 39 1
46 39 40 1
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