| Entry |
|
|---|
| Name |
Amfenac (INN) |
|---|
| Formula |
C15H13NO3
|
|---|
| Exact mass |
255.0895
|
|---|
| Mol weight |
255.27
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01906 Anti-inflammatory drug, acetic acid derivatives
DG01898 Anti-inflammatory drug, phenylacetic acid derivatives
|
|---|
| Remark |
|
|---|
| Efficacy |
Analgesic, Anti-inflammatory, Antipyretic, COX inhibitor |
|---|
| Comment |
Phenylacetic acid derivative
Nonsteroidal anti-inflammatory drug (NSAID)
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
|
|---|
| Brite |
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01906 Anti-inflammatory drug, acetic acid derivatives
DG01898 Anti-inflammatory drug, phenylacetic acid derivatives
DG01249 Amfenac
D07443 Amfenac
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Prostaglandin synthase
PTGS1 (COX1)
D07443 Amfenac (INN)
PTGS2 (COX2)
D07443 Amfenac (INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01906 Anti-inflammatory drug, acetic acid derivatives
DG01898 Anti-inflammatory drug, phenylacetic acid derivatives
DG01249 Amfenac
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 19
1 C8x C 18.6900 -17.9200
2 C8x C 18.6900 -19.3200
3 C8x C 19.9500 -20.0200
4 C8x C 21.1400 -19.3200
5 C8y C 21.1400 -17.9200
6 C8x C 19.9500 -17.2200
7 C5a C 22.3300 -17.2200
8 C8y C 23.5200 -17.9200
9 O5a O 22.3300 -15.8200
10 C8x C 23.5200 -19.3200
11 C8x C 24.7800 -20.0200
12 C8x C 25.9700 -19.3200
13 C8y C 25.9700 -17.9200
14 C8y C 24.7800 -17.2200
15 N1a N 24.7800 -15.8200
16 C1b C 27.1600 -17.2200
17 C6a C 28.4200 -17.9200
18 O6a O 29.6100 -17.2200
19 O6a O 28.4200 -19.3200
BOND 20
1 2 3 1
2 3 4 2
3 4 5 1
4 5 6 2
5 6 1 1
6 8 10 2
7 10 11 1
8 11 12 2
9 12 13 1
10 13 14 2
11 14 8 1
12 14 15 1
13 5 7 1
14 13 16 1
15 16 17 1
16 7 8 1
17 17 18 1
18 1 2 2
19 17 19 2
20 7 9 2
|
|---|
