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DRUG: Nonacog gamma

Entry

D10538                      Drug

Name

Nonacog gamma (INN);
Nonacog gamma (genetical recombination) (JAN);
Rixubis (TN)

Sequence

YNSGKLXXFV QGNLXRXCMX XKCSFXXARX VFXNTXRTTX FWKQYVDGDQ CESNPCLNGG
SCKDDINSYE CWCPFGFEGK NCELDVTCNI KNGRCEQFCK NSADNKVVCS CTEGYRLAEN
QKSCEPAVPF PCGRVSVSQT SKLTRAEAVF PDVDYVNSTE AETILDNITQ STQSFNDFTR
VVGGEDAKPG QFPWQVVLNG KVDAFCGGSI VNEKWIVTAA HCVETGVKIT VVAGEHNIEE
TEHTEQKRNV IRIIPHHNYN AAINKYNHDI ALLELDEPLV LNSYVTPICI ADKEYTNIFL
KFGSGYVSGW GRVFHKGRSA LVLQYLRVPL VDRATCLRST KFTIYNNMFC AGFHEGGRDS
CQGDSGGPHV TEVEGTSFLT GIISWGEECA MKGKYGIYTK VSRYVNWIKE KTKLT
(Disulfide bridge: 18-23, 51-62, 56-71, 73-82, 88-99, 95-109, 111-124, 132-289, 206-222, 336-350, 361-389)

Type

Peptide

Class

Blood modifier agent
DG02016  Hemostatics
  DG02014  Blood coagulation accelerant
   DG02013  Blood coagulation factor

Remark

ATC code:

B02BD04

Chemical structure group:

DG00171

Product (DG00171):

D08797<JP/US> D08794<JP> D05201<JP> D10757<JP> D10770<JP>

Efficacy

Bleeding suppressant, Replenisher (coagulation factor)

Comment

recombination blood-coagulation factor IX (synthetic human) [HSA:2158] [KO:K01321]

Interaction

Brite

Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
B BLOOD AND BLOOD FORMING ORGANS
  B02 ANTIHEMORRHAGICS
   B02B VITAMIN K AND OTHER HEMOSTATICS
    B02BD Blood coagulation factors
     B02BD04 Coagulation factor IX
      D10538  Nonacog gamma (INN)
Drug groups [BR:br08330]
Blood modifier agent
  DG02016  Hemostatics
   DG02014  Blood coagulation accelerant
    DG02013  Blood coagulation factor
     DG00171  Blood coagulation factor IX
      D10538  Nonacog gamma
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
  D10538
New drug approvals in Japan [br08318.html]
Drugs with new active ingredients
  D10538
Drug groups [BR:br08330]
Blood modifier agent
  DG02016  Hemostatics
   DG02014  Blood coagulation accelerant
    DG02013  Blood coagulation factor
     DG00171  Blood coagulation factor IX

Other DBs

PubChem:

254741500

LinkDB

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