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KEGG   DRUG: Belantamab mafodotin
Entry
D11595                      Drug                                   
Name
Belantamab mafodotin (USAN);
Belantamab mafodotin (genetical recombination) (JAN);
Belantamab mafodotin-blmf;
Blenrep (TN)
Formula
C6484H10008N1728O2030S44. (C49H66N6O11)4
Exact mass
149625.9884
Mol weight
149718.46
Remark
ATC code: L01FX15
Efficacy
Antineoplastic
  Disease
Multiple myeloma [DS:H00010]
  Type
Antibody-drug conjugate
Comment
Treatment of multiple myeloma
Target
TNFRSF17 (BCMA, CD269) [HSA:608] [KO:K05153]
TUBB [HSA:10381 10382 10383 203068 347688 347733 7280 81027 84617] [KO:K07375]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04672  Intestinal immune network for IgA production
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01F MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES
    L01FX Other monoclonal antibodies and antibody drug conjugates
     L01FX15 Belantamab mafodotin
      D11595  Belantamab mafodotin (USAN)
USP drug classification [BR:br08302]
 Antineoplastics
  Monoclonal Antibody/Antibody-Drug Conjugate
   Belantamab Mafodotin
    D11595  Belantamab mafodotin (USAN)
Target-based classification of drugs [BR:br08310]
 Cytokines and receptors
  Cytokine receptors
   Tumor necrosis factor receptors
    TNFRSF17 (BCMA, CD269)
     D11595  Belantamab mafodotin (USAN)
 Not elsewhere classified
  Cellular process
   Cytoskeleton
    TUBB
     D11595  Belantamab mafodotin (USAN)
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D11595
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D11595
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D11595
Other DBs
PubChem: 405226462
LinkDB

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