| Entry |
|
|---|
| Name |
Pebezertinib (USAN) |
|---|
| Formula |
C24H19F4N7O
|
|---|
| Exact mass |
497.1587
|
|---|
| Mol weight |
497.45
|
|---|
| Structure |
|
|---|
| Class |
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
DG03162 EGFR inhibitor
|
|---|
| Efficacy |
Antineoplastic, Receptor tyrosine kinase inhibitor |
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
DG03162 EGFR inhibitor
D12859 Pebezertinib
Target-based classification of drugs [BR:br08310]
Protein kinases
Receptor tyrosine kinases (RTK)
EGFR family
EGFR* [HSA_VAR:1956v2]
D12859 Pebezertinib (USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 36
1 C2b C 19.9798 -23.7467
2 C5a C 21.1726 -24.4483
3 N1b N 22.3655 -23.7467
4 O5a O 21.1726 -25.8517
5 C2a C 18.7869 -24.4483
6 C8y C 22.3655 -22.3433
7 C8x C 23.5583 -21.6417
8 C8x C 23.5583 -20.2383
9 C8y C 22.3655 -19.5366
10 C8y C 21.1726 -20.2383
11 C8x C 21.1726 -21.6417
12 X F 22.3655 -18.1333
13 N1b N 19.9798 -19.5366
14 C8y C 19.9798 -18.1333
15 N5x N 21.1726 -17.4316
16 C8y C 21.1726 -16.0283
17 N5x N 19.9798 -15.3266
18 C8x C 18.7168 -16.0283
19 C8y C 18.7168 -17.4316
20 N1b N 22.3908 -15.3315
21 C8y C 23.5821 -16.0260
22 C8y C 17.5073 -18.1433
23 C8x C 16.2947 -17.4564
24 C8x C 15.0851 -18.1679
25 C8y C 15.0965 -19.5712
26 C8x C 16.3091 -20.2582
27 C8x C 17.5187 -19.5466
28 C1d C 13.8816 -20.2861
29 X F 12.6663 -20.9878
30 X F 13.1800 -19.0708
31 X F 14.5833 -21.5015
32 C8x C 23.5327 -17.4314
33 N5x N 24.8509 -17.9118
34 N4y N 25.7152 -16.8065
35 C8x C 24.9311 -15.6431
36 C1a C 27.1357 -16.7866
BOND 39
1 1 2 1
2 2 3 1
3 2 4 2
4 1 5 2
5 3 6 1
6 6 7 2
7 7 8 1
8 8 9 2
9 9 10 1
10 10 11 2
11 6 11 1
12 9 12 1
13 10 13 1
14 13 14 1
15 14 15 2
16 15 16 1
17 16 17 2
18 17 18 1
19 18 19 2
20 14 19 1
21 16 20 1
22 20 21 1
23 19 22 1
24 22 23 2
25 23 24 1
26 24 25 2
27 25 26 1
28 26 27 2
29 22 27 1
30 25 28 1
31 28 29 1
32 28 30 1
33 28 31 1
34 21 32 1
35 32 33 2
36 33 34 1
37 34 35 1
38 21 35 2
39 34 36 1
|
|---|
