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KEGG   DISEASE: Streptococcal infection
Entry
H00333                      Disease                                
Name
Streptococcal infection
  Subgroup
Group A streptococcal pharyngitis [DS:H01424]
Invasive streptococcal disease [DS:H01426]
Necrotizing fasciitis [DS:H01455]
Scarlet fever [DS:H01515]
Erysipelas [DS:H01517]
Description
Streptococci are gram-positive bacteria. Among the beta-hemolytic streptococci, Streptococcus pyogenes (Group A streptococci, GAS) and Streptococcus agalactiae (Group B streptococci, GBS) are major human pathogens. GAS causes over 600 million cases of infections each year, ranging from mild pharyngitis to severe streptococcal toxic shock-like syndrome (STSS), and GBS causes neonatal invasive infections including sepsis, pneumonia, and meningitis.
Category
Bacterial infectious disease
Brite
Human diseases in ICD-11 classification [BR:br08403]
 01 Certain infectious or parasitic diseases
  Certain staphylococcal or streptococcal diseases
   1B51  Streptococcal pharyngitis
    H00333  Streptococcal infection
   1B53  Meningitis due to Streptococcus
    H00333  Streptococcal infection
 12 Diseases of the respiratory system
  Lung infections
   CA40  Pneumonia
    H00333  Streptococcal infection
Genome-based classification of infectious diseases [BR:br08401]
 Bacterial infections
  Infections caused by Gram-positive bacteria
   H00333  Streptococcal infection
Pathogen
Streptococcus pyogenes [GN:spy spz spym spya spm spg sps sph spi spj spk spf spa spb stg stx soz stz spyh spyo]
Streptococcus agalactiae [GN:sag san sak sagt sagn sagj]
pore-forming toxin [KO:K11031 K11045 K11046]
pore-forming toxin [KO:K11052]
superantigen [KO:K11040]
ADP-ribosyltransferase SpyA [KO:K11044]
Drug
Clindamycin phosphate [DR:D01073]
Clindamycin palmitate hydrochloride [DR:D01990]
Clindamycin hydrochloride [DR:D02132]
Other DBs
ICD-11: 1B51 1B53 CA40.07
ICD-10: A40 A49.1 G00.2 J02.0 J03.0 J15.3 J15.4 M60.0A P36.0 P36.1
MeSH: D013290
Reference
  Authors
Cole JN, Barnett TC, Nizet V, Walker MJ
  Title
Molecular insight into invasive group A streptococcal disease.
  Journal
Nat Rev Microbiol 9:724-36 (2011)
DOI:10.1038/nrmicro2648
Reference
  Authors
Lynskey NN, Lawrenson RA, Sriskandan S
  Title
New understandings in Streptococcus pyogenes.
  Journal
Curr Opin Infect Dis 24:196-202 (2011)
DOI:10.1097/QCO.0b013e3283458f7e
Reference
  Authors
Melin P
  Title
Neonatal group B streptococcal disease: from pathogenesis to preventive strategies.
  Journal
Clin Microbiol Infect 17:1294-303 (2011)
DOI:10.1111/j.1469-0691.2011.03576.x
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