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KEGG   DISEASE: Anaerobic infection
Entry
H01410                      Disease                                
Name
Anaerobic infection
  Subgroup
Foodborne Clostridium perfringens intoxication [DS:H00335]
Gas gangrene [DS:H00336]
Botulism [DS:H00339]
Tetanus [DS:H00337]
Pseudomembranous colitis [DS:H00338]
Propionibacterium acnes infection [DS:H01446]
Acne vulgaris [DS:H01445]
Periodontal diseases [DS:H01408]
Acute necrotizing ulcerative gingivitis [DS:H01440]
Bacteroides infection [DS:H02076]
Description
Anaerobic infections are common and some are serious with a high mortality rate. The clinically important anaerobes are several genera of Gram-negative rods (Bacteroides, Prevotella, Porphyromonas, Fusobacterium and Bilophila). Among the Gram-positive anaerobes, there are cocci (primarily Peptostreptococcus) and sporeforming (Clostridium) and non-sporeforming bacilli (especially Actinomyces and Propionibacterium). In terms of frequency, there are four major sites of anaerobic infection - pleuropulmonary, intra-abdominal, female genital tract, and skin and soft tissue infections (with or without involvement of underlying bone). Infectious diseases caused by these anaerobes include following symptoms, bacteremia, brain abscess, neck space infections and infections following head and neck surgery, chronic sinusitis and otitis media, dental and oral infections, pleuropulmonary infections, intra-abdominal infections, female genital tract infections, non-puerperal breast abscesses and diabetic foot ulcers.
Category
Bacterial infectious disease
Brite
Genome-based classification of infectious diseases [BR:br08401]
 Bacterial infections
  Infections caused by bacteria
   H01410  Anaerobic infection
Drug
Metronidazole [DR:D00409]
Comment
Infectious disease caused by Bacteroides spp., Prevotella spp., Porphyromonas spp., Porphyromonas spp., Fusobacterium spp., Peptostreptococcus spp., Clostridium spp., Bilophila spp. and Actinomyces spp..
Other DBs
ICD-10: A49 B96
Reference
  Authors
Finegold SM
  Title
Anaerobic infections in humans: an overview.
  Journal
Anaerobe 1:3-9 (1995)
DOI:10.1016/S1075-9964(95)80340-8
Reference
  Authors
Goto T, Yamashita A, Hirakawa H, Matsutani M, Todo K, Ohshima K, Toh H, Miyamoto K, Kuhara S, Hattori M, Shimizu T, Akimoto S.
  Title
Complete genome sequence of Finegoldia magna, an anaerobic opportunistic pathogen.
  Journal
DNA Res 15:39-47 (2008)
DOI:10.1093/dnares/dsm030
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