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KEGG   DISEASE: Thyroid eye disease
Entry
H02402                      Disease                                
Name
Thyroid eye disease;
Graves ophthalmopathy
Description
Thyroid eye disease (TED), also called Graves ophthalmopathy, is an autoimmune disorder of the retrobulbar tissue. It is the most frequent extrathyroidal manifestation of Graves disease [DS:H00082]. Although TED is often associated with hyperthyroidism, it may occur in primary hypothyroidism, and sometimes in euthyroid individuals.
Category
Immune system disease
Brite
Human diseases in ICD-11 classification [BR:br08403]
 05 Endocrine, nutritional or metabolic diseases
  Endocrine diseases
   Disorders of the thyroid gland or thyroid hormones system
    5A02  Thyrotoxicosis
     H02402  Thyroid eye disease
Drug
Teprotumumab [DR:D09680]
Other DBs
ICD-11: 5A02.0
ICD-10: E05.0
MeSH: D049970
OMIM: 275000
Reference
  Authors
Weiler DL
  Title
Thyroid eye disease: a review.
  Journal
Clin Exp Optom 100:20-25 (2017)
DOI:10.1111/cxo.12472
Reference
  Authors
Mallika P, Tan A, Aziz S, Alwi SS, Chong M, Vanitha R, Intan G
  Title
Thyroid associated ophthalmopathy - a review.
  Journal
Malays Fam Physician 4:8-14 (2009)
Reference
  Authors
Marcocci C, Bartalena L, Tanda ML, Manetti L, Dell'Unto E, Rocchi R, Barbesino G, Mazzi B, Bartolomei MP, Lepri P, Cartei F, Nardi M, Pinchera A
  Title
Comparison of the effectiveness and tolerability of intravenous or oral glucocorticoids associated with orbital radiotherapy in the management of severe  Graves' ophthalmopathy: results of a prospective, single-blind, randomized study.
  Journal
J Clin Endocrinol Metab 86:3562-7 (2001)
DOI:10.1210/jcem.86.8.7737
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