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ORTHOLOGY: K04946

Entry

K04946                      KO

Symbol

KCNT1, KNA1.1

Name

potassium channel subfamily T member 1

Disease

H00606

Early infantile epileptic encephalopathy

H00807

Nocturnal frontal lobe epilepsy

H01815

Malignant migrating partial seizures in infancy

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04946  KCNT1, KNA1.1; potassium channel subfamily T member 1
Ion channels [BR:ko04040]
Voltage-gated cation channels
  Potassium channel, calcium- and sodium-activated (KCa/KNa)
   K04946  KCNT1, KNA1.1; potassium channel subfamily T member 1

Other DBs

TC:	1.A.1.3.4 1.A.1.3.7 1.A.1.3.8

Genes

HSA:	57582(KCNT1)

PTR:	464846(KCNT1)

PPS:	100970672(KCNT1)

GGO:	101142551(KCNT1)

PON:	100436526(KCNT1)

PPYG:

129043700(KCNT1)

HMH:	116475851(KCNT1)

SSYN:

129478696(KCNT1)

MCC:	721830(KCNT1)

MCF:	102131815(KCNT1)

MTHB:

126936886

MNI:	105471910(KCNT1)

CSAB:

103239645(KCNT1)

CATY:

105580656(KCNT1)

PANU:

101003576(KCNT1)

TGE:	112608095(KCNT1)

MLEU:

105543241(KCNT1)

RRO:	104669689(KCNT1)

RBB:	108513021(KCNT1)

TFN:	117099174(KCNT1)

PTEH:

111553114(KCNT1)

CANG:

105522723(KCNT1)

CJC:	100386822(KCNT1)

SBQ:	101033655(KCNT1)

CIMI:

108287332(KCNT1)

ANAN:

105712177(KCNT1)

CSYR:

103273224(KCNT1)

MMUR:

105880800(KCNT1)

LCAT:

123646344(KCNT1)

PCOQ:

105818668(KCNT1)

OGA:	100941782(KCNT1)

MMU:	227632(Kcnt1)

MCAL:

110311338(Kcnt1)

MPAH:

110317686(Kcnt1)

RNO:	60444(Kcnt1)

MCOC:

116089834(Kcnt1)

ANU:	117711337(Kcnt1)

MUN:	110550832(Kcnt1)

CGE:	100758898(Kcnt1)

MAUA:

101842826(Kcnt1)

PROB:

127222616(Kcnt1)

PLEU:

114692804(Kcnt1)

MORG:

121462679(Kcnt1)

MFOT:

126509385

AAMP:

119818721(Kcnt1)

NGI:	103741197(Kcnt1)

HGL:	101718795(Kcnt1)

CPOC:

100734549(Kcnt1)

CCAN:

109686618(Kcnt1)

DORD:

105995593(Kcnt1)

DSP:	122108939(Kcnt1)

PLOP:

125351403(Kcnt1)

NCAR:

124964414

MMMA:

107159133(Kcnt1)

OPI:	101533441(KCNT1)

TUP:	102477254(KCNT1)

GVR:

103604782

CFA:	491258(KCNT1)

CLUD:

112677424(KCNT1)

VVP:	112906892(KCNT1)

VLG:	121473726(KCNT1)

NPO:	129510121(KCNT1)

AML:	100465679(KCNT1)

UAH:	113266291(KCNT1)

UAR:	123802805(KCNT1)

ELK:

111145468

LLV:

125082907

MPUF:

101684817(KCNT1)

MNP:	132024256(KCNT1)

MLK:	131812555(KCNT1)

NVS:	122917105(KCNT1)

ORO:	101362367(KCNT1)

EJU:	114201900(KCNT1)

ZCA:	113934581(KCNT1)

MLX:	118018089(KCNT1)

NSU:	110581228(KCNT1)

LWW:	102744455(KCNT1)

FCA:	101091413(KCNT1)

PYU:	121022832(KCNT1)

PBG:	122475422(KCNT1)

PVIV:

125150754(KCNT1)

LRUF:

124522451

PPAD:

109258760(KCNT1)

PUC:

125923423

AJU:

113596830

HHV:	120221958(KCNT1)

BTA:	529468(KCNT1)

BOM:	102281859(KCNT1)

BIU:	109566579(KCNT1)

BBUB:

102407778(KCNT1)

BBIS:

104988999(KCNT1)

CHX:	102188508(KCNT1)

OAS:	101118349(KCNT1)

BTAX:

128055271(KCNT1)

ODA:	120852135(KCNT1)

CCAD:

122442312(KCNT1)

MBEZ:

129539780(KCNT1)

SSC:	100519817(KCNT1)

CFR:	102510167(KCNT1)

CBAI:

105069764(KCNT1)

CDK:	105106012(KCNT1)

VPC:	102536237(KCNT1)

BACU:

103020377(KCNT1)

BMUS:

118896872(KCNT1)

LVE:	103083325(KCNT1)

OOR:	101280123(KCNT1)

DLE:	111177027(KCNT1)

PCAD:

102994913(KCNT1)

PSIU:

116755108(KCNT1)

NASI:

112411422(KCNT1)

ECB:	100068421(KCNT1)

EPZ:	103560534(KCNT1)

EAI:	106845545(KCNT1)

MYB:	102260580(KCNT1)

MYD:	107185093(KCNT1)

MMYO:

118655329(KCNT1)

MDT:	132212640(KCNT1)

PKL:	118707006(KCNT1)

EFUS:

103296077(KCNT1)

MNA:	107536170(KCNT1)

DRO:	112306392(KCNT1)

SHON:

118980060(KCNT1)

AJM:	119036104(KCNT1)

PDIC:

114506361(KCNT1)

PHAS:

123823573(KCNT1)

MMF:	118629669(KCNT1)

PPAM:

129079558(KCNT1)

HAI:	109381525(KCNT1)

RFQ:	117032039(KCNT1)

PALE:

102887519(KCNT1)

PGIG:

120599768(KCNT1)

PVP:	105298638(KCNT1)

RAY:	107514863(KCNT1)

MJV:	108407785(KCNT1)

TOD:	119230776(KCNT1)

SARA:

101541796(KCNT1)

SETR:

126009221(KCNT1)

LAV:	100660648(KCNT1)

TMU:

101341531

ETF:	101648309(KCNT1)

MDO:	100016518(KCNT1)

GAS:	123235174(KCNT1)

SHR:	100933191(KCNT1)

AFZ:

127550995

PCW:	110205323(KCNT1)

TVP:	118843168(KCNT1)

OAA:	100681774(KCNT1)

GGA:	395248(KCNT1)

PCOC:

116234348(KCNT1)

MGP:	100549521(KCNT1)

CJO:	107321706(KCNT1)

TPAI:

128073010(KCNT1)

LMUT:

125702472(KCNT1)

NMEL:

110406947

APLA:

101797615(KCNT1)

ACYG:

106040655(KCNT1)

CATA:

118252334(KCNT1)

AFUL:

116496993(KCNT1)

TGU:	100227933(KCNT1)

LSR:	110477648(KCNT1)

SCAN:

103818944(KCNT1)

PMOA:

120512441(KCNT1)

OTC:	121337064(KCNT1)

PRUF:

121362461(KCNT1)

GFR:	102039927(KCNT1)

FAB:	101818328(KCNT1)

OMA:	130260191(KCNT1)

PHI:	102111899(KCNT1)

PMAJ:

107212186(KCNT1)

CCAE:

111937080(KCNT1)

CCW:	104688502(KCNT1)

CBRC:

103623226(KCNT1)

ETL:	114058489(KCNT1)

ZAB:	102071612(KCNT1)

ZLE:	135455171(KCNT1)

ACHL:

103802245(KCNT1)

SVG:	106855443(KCNT1)

MMEA:

130582264(KCNT1)

HRT:	120761791(KCNT1)

SATI:

136369918(KCNT1)

FPG:	101911435(KCNT1)

FCH:	102045978(KCNT1)

NNT:

104412033

SHAB:

115617031(KCNT1)

ACUN:

113486643(KCNT1)

TALA:

104369430(KCNT1)

ACHC:

115335495(KCNT1)

HLE:	104833833(KCNT1)

AGEN:

126052302

GCL:

127023704

CSTI:

104556793(KCNT1)

LDI:	104345205(KCNT1)

DPUB:

104306491(KCNT1)

AVIT:

104272236

BRHI:

104489047(KCNT1)

EGZ:	104131357(KCNT1)

NNI:	104023305(KCNT1)

PADL:

103915329(KCNT1)

AFOR:

103900063(KCNT1)

CLV:	102091885(KCNT1)

MUI:	104543992(KCNT1)

EHS:

104510984

CUCA:

104066847(KCNT1)

TEO:	104380776(KCNT1)

OHA:	104335127(KCNT1)

ACAR:

104531317

CPEA:

104389798(KCNT1)

CVF:	104292910(KCNT1)

RTD:	128917682(KCNT1)

AAM:	106486892(KCNT1)

AROW:

112964258(KCNT1)

NPD:	112955998(KCNT1)

TGT:

104568131

DNE:	112979944(KCNT1)

SCAM:

104138273(KCNT1)

ASN:	102383261(KCNT1)

AMJ:	102557641(KCNT1)

CPOO:

109314138(KCNT1)

GGN:	109293044(KCNT1)

PSS:	102463805(KCNT1)

CMY:	102930567(KCNT1)

CCAY:

125623595(KCNT1)

DCC:	119844241(KCNT1)

CPIC:

101933342(KCNT1)

TST:	117867147(KCNT1)

CABI:

116817440(KCNT1)

MRV:	120386899(KCNT1)

ACS:	100560488(kcnt1)

ASAO:

132763667(KCNT1)

PVT:	110087481(KCNT1)

SUND:

121936954(KCNT1)

PBI:	103059154(KCNT1)

PMUR:

107295537(KCNT1) 107297717

CTIG:

120300734(KCNT1)

PGUT:

117670264(KCNT1)

APRI:

131186157(KCNT1)

PTEX:

113443849(KCNT1)

NSS:	113424788(KCNT1)

VKO:	123028282(KCNT1)

PMUA:

114589094(KCNT1)

PRAF:

128406922(KCNT1)

ZVI:	118084449(KCNT1)

HCG:	128338972(KCNT1)

GJA:	107118790(KCNT1)

STOW:

125441841(KCNT1)

EMC:	129342321(KCNT1)

XLA:	108698853(kcnt1.L) 108700501(kcnt1.S)

XTR:	100316919(kcnt1)

NPR:	108792851(KCNT1)

RTEM:

120913873(KCNT1)

BBUF:

120977720(KCNT1)

BGAR:

122919462(KCNT1)

MUO:	115473006(KCNT1)

GSH:	117368527(KCNT1)

DRE:	100004419(kcnt1) 563670(si:dkey-21e5.1)

SRX:	107720246 107745529

SANH:

107661619 107672542 107699766

SGH:	107552607 107585680(kcnt1) 107587698 107599361

CCAR:

109062450 109062459 109066397

CAUA:

113038899 113049669 113077142 113079377 113097281

CGIB:

127942253 127958368 127985483 127997491

PTET:

122332594(kcnt1a) 122346029(kcnt1b)

LROH:

127152078(kcnt1a) 127165081(kcnt1b)

OMC:	131529528(kcnt1a) 131540479(kcnt1b)

PPRM:

120472065(kcnt1b) 120484199(kcnt1a)

RKG:	130072041(kcnt1b) 130079887(kcnt1a)

MAMB:

125253039(kcnt1a) 125267564(kcnt1b)

CIDE:

127504193 127513602

CERY:

137012441(kcnt1a) 137033651(kcnt1b)

MASI:

127419343 127429296 127431171 127433703

TROS:

130547384(kcnt1b) 130570101(kcnt1a)

TDW:	130407880(kcnt1a) 130419037(kcnt1b)

MANU:

129424139(kcnt1a) 129441028(kcnt1b)

IPU:	108256037(kcnt1b) 108278825(kcnt1a)

IFU:	128598925(kcnt1b) 128622568(kcnt1a)

PHYP:

113535424 113537038

SMEO:

124380557(kcnt1b) 124398401(kcnt1a)

TFD:	113637565(kcnt1b) 113663627(kcnt1a)

TVC:	132855007(kcnt1b) 132859810(kcnt1a)

TRN:	134330048(kcnt1a) 134335202

AMEX:

103034948(kcnt1a) 103038166(kcnt1b)

CMAO:

118820594(kcnt1) 118827476(si:dkey-21e5.1)

EEE:	113572935 113591770

CHAR:

105902864(kcnt1b)

TRU:	101069866 101071880

TFS:	130516862(kcnt1a) 130525337(kcnt1b)

TNG:	GSTEN00029017G001 GSTEN00034705G001

LCO:	104923668(kcnt1) 104924505

NCC:	104961280(kcnt1)

TBEN:

117473143 117476759

CGOB:

115013121(kcnt1)

PGEO:

117452474 117456373(kcnt1)

GACU:

117552002(si:dkey-21e5.1) 117556764

EMAC:

134867993(kcnt1a) 134874062(kcnt1b)

ELY:	117252772 117269234(kcnt1)

EFO:	125889876(kcnt1b) 125905474(kcnt1a)

PLEP:

121944359(kcnt1b) 121959719(kcnt1a)

SLUC:

116054316 116063019(kcnt1)

ECRA:

117944618(si:dkey-21e5.1) 117959848(kcnt1)

ESP:	116689110 116704188

PFLV:

114555123(kcnt1) 114570887

GAT:	120831144(kcnt1b) 120831681(kcnt1a)

PPUG:

119224531(si:dkey-21e5.1) 119226309(kcnt1)

AFB:	129100930(kcnt1b) 129102185(kcnt1a)

CLUM:

117736270(si:dkey-21e5.1) 117740475(kcnt1)

PSWI:

130197111(kcnt1b) 130205366(kcnt1a)

MSAM:

119891803(si:dkey-21e5.1) 119914599(kcnt1)

SCHU:

122865885(kcnt1a) 122876884(kcnt1b)

CUD:	121509918(kcnt1b) 121525377(kcnt1a)

ALAT:

119020020(si:dkey-21e5.1) 119029574

MZE:	101469894 101482114

ONL:	100694521 100698615

OAU:	116326085(kcnt1b) 116331791(kcnt1a)

OLA:	101161907 101174597

OML:	112147954 112162864

CSAI:

133451468(kcnt1b) 133454571(kcnt1a)

XMA:	102225348 102234946

XCO:	114150222 114154529

XHE:	116725017 116729456

PRET:

103469893(kcnt1) 103473438

PFOR:

103141966 103151455

PLAI:

106936451 106954257(kcnt1)

PMEI:

106922573 106930904

GAF:	122828464(kcnt1b) 122846801(kcnt1a)

PPRL:

129365704(kcnt1b) 129374308(kcnt1a)

CVG:	107089751 107098094

CTUL:

119776515(kcnt1) 119793215(si:dkey-21e5.1)

GMU:	124872052(kcnt1a) 124877593(kcnt1b)

NFU:	107374761 107386274

KMR:	108230896(kcnt1) 108233725(si:dkey-21e5.1)

ALIM:

106516271 106528760

NWH:	119413199(kcnt1b) 119424747(kcnt1a)

AOCE:

111569815 111586035

MCEP:

124997074(kcnt1a) 125011829(kcnt1b)

CSEM:

103390441 103397829

POV:	109626115 109636998

SSEN:

122758231(kcnt1a) 122769299(kcnt1b)

HHIP:

117768148(si:dkey-21e5.1) 117771712(kcnt1)

HSP:	118098109(kcnt1a) 124852375(kcnt1b)

PPLT:

128424849(kcnt1a) 128437891

SMAU:

118285268(kcnt1a) 118313327(kcnt1b)

LCF:	108874105(kcnt1a) 108874602

SDU:	111236174 111236439(kcnt1)

SLAL:

111652413 111663066

XGL:	120804637(kcnt1b) 120806760(kcnt1a)

HCQ:

109525351

SSCV:

125994275

SBIA:

133491272(kcnt1a) 133499871(kcnt1b)

PEE:	133400019 133413597(kcnt1a)

PTAO:

133475049 133490092(kcnt1a)

BPEC:

110157428 110174759

MALB:

109959128 109972371

BSPL:

114861932(kcnt1b) 114866546(kcnt1a)

SJO:	128364289(kcnt1b) 128380067(kcnt1a)

SASA:

106579798 106585221

STRU:

115164158 115200482

OTW:	112248842 112263911

OMY:	110525997 110536366

OGO:	124034061 124036573

ONE:	115112497(kcnt1) 115140707

OKI:	109874017 109894950

OKE:	118377657 118393513(kcnt1b)

SALP:

111957582 111974373

SNH:	120036633 120051577(si:dkey-21e5.1)

CCLU:

121558072 121585199

ELS:	105014068(kcnt1)

SFM:	108920175 108936235

PKI:

111841850

AANG:

118212612(kcnt1)

LOC:	102686091(kcnt1)

PSPA:

121307480 121307496

ARUT:

117396751 117973875

PSEX:

120535477

LCM:	102353681(KCNT1)

CMK:	103183063(kcnt1b)

RTP:	109911503(kcnt1b)

CPLA:

122564943(kcnt1b)

HOC:

132825911

LERI:

129712006(kcnt1b)

PMRN:

116953115(KCNT1) 116955313

LRJ:	133354597(KCNT1) 133360217

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

ARUN:

DME:	Dmel_CG42732(SLO2)

DER:

6542537

DSI:	Dsimw501_GD25995(Dsim_GD25995)

DYA:	Dyak_GE21644

DSR:

110191670

DPO:

4804232

DPE:

6591129

DMN:	108159238 117191458

DWI:

6645994

DGR:

6559773

DMO:	Dmoj_GI20202

DAZ:

DNV:

DHE:

CCAT:

BOD:

BDR:

RZE:

AOQ:

TDA:	119674981 119681438

MDE:

SCAC:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

109408817 109622509 115265424

ASUA:

134218133

CQU:	CpipJ_CPIJ000215

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:	105678128(SLO2)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

DVV:

NVL:

DCOR:

135793903(SLO2)

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_209674

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

SLIU:

OFU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CFEL:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

106681401(SLO2)

NLU:

111057314

MQU:	128993980 128995917

PHU:	Phum_PHUM562900

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

FCD:	110846852 110846987

DPX:	DAPPUDRAFT_61826

DMK:

DPZ:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

HAZT:

ISC:

DSV:

RSAN:

RMP:

TUT:

DPTE:

DFR:

CSCU:

CVS:	136983689(SLO2)

PTEP:

107438721 107451644

ABRU:

129957325 129972386

UDV:	129220636 129222864

SDM:	118189638 118201805

LPOL:

106459782 106460549 106474492

CEL:	CELE_F08B12.3(slo-2)

CBR:	CBG_17348(Cbr-slo-2)

CRQ:	GCK72_023786

NAI:	NECAME_02653

LOA:	LOAG_17482

HRO:	HELRODRAFT_111253

LGI:	LOTGIDRAFT_91366

PVUL:

126808461

PCAN:

112561410 112563258 112575225

GAE:

121384263

HRF:	124131699 124138395

HRJ:

124278719

MYI:	110452145 110456138 110458700 110466175

PMAX:

MMER:

RPHI:

DPOL:

MAEA:

128205617 128205783 128223884

OBI:

OSN:

LJP:

LAK:

LLON:

NVE:

EPA:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

AQU:

MBR:	MONBRDRAFT_27459

SRE:	PTSG_07747

SPAR:

SPRG_00826

» show all

Reference

PMID:10196543

Authors

Joiner WJ, Tang MD, Wang LY, Dworetzky SI, Boissard CG, Gan L, Gribkoff VK, Kaczmarek LK

Title

Formation of intermediate-conductance calcium-activated potassium channels by interaction of Slack and Slo subunits.

Journal

Nat Neurosci 1:462-9 (1998)
DOI:10.1038/2176

Sequence

[rno:60444]

LinkDB

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