BBC Russian

ORTHOLOGY: K09831

Entry

K09831                      KO

Symbol

ERG5, CYP61A

Name

sterol 22-desaturase [EC:1.14.19.41]

Pathway

map00100

Steroid biosynthesis

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

Module

M00102

Ergocalciferol biosynthesis, FPP => ergosterol/ergocalciferol

Reaction

R07506

ergosta-5,7,24(28)-trien-3beta-ol,NADPH:oxygen oxidoreductase (22,23-dehydrogenating)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00100 Steroid biosynthesis
    K09831  ERG5, CYP61A; sterol 22-desaturase
09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K09831  ERG5, CYP61A; sterol 22-desaturase
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.19  With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
    1.14.19.41  sterol 22-desaturase
     K09831  ERG5, CYP61A; sterol 22-desaturase
Cytochrome P450 [BR:ko00199]
Cytochrome P450, fungi type
  CYP61 family
   K09831  ERG5, CYP61A; sterol 22-desaturase

Other DBs

COG:

COG2124

GO:

0000249

Genes

SCE:	YMR015C(ERG5)

SEUB:

DI49_4102

SPAO:

SPAR_M01390

AGO:	AGOS_ABR053C

KLA:	KLLA0_D11242g

KMX:	KLMA_60417(cyp524A1)

LTH:	KLTH0D07832g

VPO:	Kpol_1056p10

ZRO:	ZYRO0E06204g

CGR:	2891731(ERG5)

NCS:	NCAS_0A12700(NCAS0A12700)

NDI:	NDAI_0B01560(NDAI0B01560)

TPF:	TPHA_0I02420(TPHA0I02420)

TBL:	TBLA_0H02650(TBLA0H02650)

TGB:	HG536_0G01250

TDL:	TDEL_0B06510(TDEL0B06510)

KAF:	KAFR_0A02110(KAFR0A02110)

KNG:	KNAG_0M02100(KNAG0M02100)

ZMK:	HG535_0G03560

DHA:	DEHA2D06182g

PIC:	PICST_73043(ERG5)

PGU:	PGUG_05085

SPAA:

SPAPADRAFT_63544(ERG5)

LEL:	PVL30_005321(ERG5)

CAL:	CAALFM_C702840CA(ERG5)

CTP:	CTRG_04983

COT:	CORT_0G04140

CDU:	CD36_72510

CTEN:

18247844(ERG5)

YLI:	2906079(YALI2_A00419g)

CLU:	CLUG_04246

CLUS:

A9F13_04g02805

CAUR:

CJI96_0004850 CJI96_0004910

SLB:	AWJ20_75(ERG5)

PPA:	PAS_chr3_0507

PKZ:	C5L36_0B12520

BNN:	FOA43_004793(ERG5)

BBRX:

BRETT_002777(ERG5)

OPA:	HPODL_01958

SLUD:

SCDLUD_004216

NCR:

NCU05278

NTE:	NEUTE1DRAFT116692(NEUTE1DRAFT_116692)

SMP:	10806154(SMAC4_01710)

PAN:	PODANSg6262 PODANSg7995

PBEL:

QC761_202070 QC761_304420(ERG5)

PPSD:

QC762_202070 QC762_304420(ERG5)

PPSP:

QC763_202070 QC763_304420(ERG5)

PPSA:

QC764_202070 QC764_304420(ERG5)

TTT:	THITE_128412

MTM:	MYCTH_73679

CTHR:

MGR:

PPEI:

PGRI:

TMN:	UCRPA7_7946

SSCK:

SPSK_00476

FGR:	FGSG_01959 FGSG_03686

FPU:	FPSE_01847 FPSE_09181

FPOA:

FPOAC1_002075 FPOAC1_006089

FVN:	FVRRES_02319 FVRRES_06686

FVR:	FVEG_07284 FVEG_08786

FOX:	FOXG_04166 FOXG_09685

NHE:	NECHADRAFT_72313 NECHADRAFT_72652

FFC:	NCS54_01269600 NCS54_01305200

FKR:	NCS57_01239900 NCS57_01291900

FMU:	J7337_010705 J7337_012541

TRE:	TRIREDRAFT_122166 TRIREDRAFT_58689

TRR:	M419DRAFT_141218 M419DRAFT_74177

TATV:

25781109(TrAtP1_001090) 25784525(TrAtP1_005351)

MAW:	19252947(ERG5_1)

MAJ:

MAA_01109

MBRN:

26239210(ERG5)

PCHM:

VFPPC_03546

CMT:

CCM_02962

AMUS:

LMH87_000586 LMH87_006973

PLJ:	28882794(PLICBS_001203) 28890467(PLICBS_009795)

PTKZ:

JDV02_004750 JDV02_007982(ERG5)

VAL:	VDBG_00192 VDBG_00755

VDA:	VDAG_00367 VDAG_08476

CFJ:	CFIO01_05732 CFIO01_13734

CLUP:

CLUP02_04776 CLUP02_14903

CHIG:

CH63R_04552 CH63R_14243

SAPO:

SAPIO_CDS4161 SAPIO_CDS7005

ELA:	UCREL1_11694

PFY:	PFICI_04403 PFICI_13034

SSL:	SS1G_09832

BFU:	BCIN_07g01120(Bcerg5)

MBE:

MBM_06688

PSCO:

LY89DRAFT_257563 LY89DRAFT_584410

GLZ:	GLAREA_02023 GLAREA_06590

ANI:	ANIA_04042

AFM:	AFUA_1G03950

ACT:	ACLA_008020 ACLA_030640

NFI:	NFIA_020740

AOR:	AO090003000253 AO090003000954

ANG:	An01g02810 An11g03230

AFV:	AFLA_000720 AFLA_001436

ALUC:

AKAW2_20450S(ERG5_1) AKAW2_80298S(ERG5_2)

ACHE:

ACHE_11570S(ERG5)

APUU:

APUU_40308A(ERG5) APUU_60358A

PCS:	N7525_005484 N7525_010907

PDP:	PDIP_21270

POU:	POX_e06874

TMF:	EYB26_008188

TRG:	TRUGW13939_00550 TRUGW13939_08662

CIM:	CIMG_05009

CPW:	CPC735_068810

URE:	UREG_06546

PBL:	PAAG_11073(PAAG_00230)

PBN:	PADG_07898

ABE:

ARB_03814

TVE:

TRV_05093

AJE:	HCAG_06013

BGH:	BDBG_03201

PNO:	SNOG_06055

PTE:

PTT_19871

PTRR:

6343165(PtrM4_119060)

BZE:	COCCADRAFT_88203

BSC:	COCSADRAFT_221542

BOR:	COCMIDRAFT_93916

AALT:

CC77DRAFT_991604

ARAB:

EKO05_0000970

ZTR:	MYCGRDRAFT_55438(CYP-70)

PFJ:	MYCFIDRAFT_49450

FFU:	CLAFUR5_02386

CBET:

CB0940_03149

BCOM:

BAUCODRAFT_489380

NPA:	UCRNP2_2755

TML:	GSTUM_00005882001

SPO:	2542469(erg5)

SOM:	SOMG_03716(erg5)

CNE:

CNF03720

CNB:

CNBF1100

CNG:	CNAG_06644

CGI:	CGB_F1500C

CDEU:

CNBG_1921

CDEP:

91090557(L203_106349)

TMS:	TREMEDRAFT_40696

TASA:

A1Q1_00690

CCAC:

CcaHIS019_0405230(ERG5)

TVS:	TRAVEDRAFT_140384

DSQ:	DICSQDRAFT_66936

PCO:	PHACADRAFT_246788

SHS:	STEHIDRAFT_123767

HIR:	HETIRDRAFT_141009(cpm111)

PSQ:	PUNSTDRAFT_59236

ADL:	AURDEDRAFT_109660

FME:	FOMMEDRAFT_106824 FOMMEDRAFT_155371

GTR:	GLOTRDRAFT_53715

RSX:	RhiXN_01858

LBC:	LACBIDRAFT_187166(ERG5)

CCI:	CC1G_01671

ABP:	AGABI1DRAFT66440(AGABI1DRAFT_66440)

ABV:	AGABI2DRAFT189837(AGABI2DRAFT_189837)

PCUB:

JR316_0000711

MRR:	Moror_12729

E1B28_009893

SCM:	SCHCO_02609502(SCHCODRAFT_02609502)

CPUT:

CONPUDRAFT_94730

SLA:	SERLADRAFT_459032

WSE:	WALSEDRAFT_69870

WIC:	J056_001310

UMA:	UMAG_00350

PFP:	PFL1_03644

SGRA:

MGL:

MRT:

MSYM:

Reference

PMID:8635732

Authors

Skaggs BA, Alexander JF, Pierson CA, Schweitzer KS, Chun KT, Koegel C, Barbuch R, Bard M

Title

Cloning and characterization of the Saccharomyces cerevisiae C-22 sterol desaturase gene, encoding a second cytochrome P-450 involved in ergosterol biosynthesis.

Journal

Gene 169:105-9 (1996)
DOI:10.1016/0378-1119(95)00770-9

Sequence

[sce:YMR015C]

LinkDB

DBGET integrated database retrieval system