KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
K17712 CYP2D6; cytochrome P450 family 2 subfamily D6
00982 Drug metabolism - cytochrome P450
K17712 CYP2D6; cytochrome P450 family 2 subfamily D6
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
K17712 CYP2D6; cytochrome P450 family 2 subfamily D6
09160 Human Diseases
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
K17712 CYP2D6; cytochrome P450 family 2 subfamily D6
09180 Brite Hierarchies
09181 Protein families: metabolism
00199 Cytochrome P450
K17712 CYP2D6; cytochrome P450 family 2 subfamily D6
Enzymes [BR:ko01000]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.14.1 unspecific monooxygenase
K17712 CYP2D6; cytochrome P450 family 2 subfamily D6
Cytochrome P450 [BR:ko00199]
Cytochrome P450, animal type
CYP2 family
K17712 CYP2D6; cytochrome P450 family 2 subfamily D6
Pai HV, Kommaddi RP, Chinta SJ, Mori T, Boyd MR, Ravindranath V
Title
A frameshift mutation and alternate splicing in human brain generate a functional form of the pseudogene cytochrome P4502D7 that demethylates codeine to morphine.