Entry |
|
Name |
|
Definition |
(ATM,ATR) -> CHEK1 -> TP53 => CDKN1A -| (CDK1+CCNB) |
Expanded |
(472,545) -> 1111 -> 7157 => 1026 -| (983+(891,9133,85417)) |
Class |
nt06230 Cell cycle (cancer)
nt06160 Human T-cell leukemia virus 1 (HTLV-1)
|
Type |
Reference
|
Pathway |
|
Gene |
472 | ATM; ATM serine/threonine kinase |
545 | ATR; ATR serine/threonine kinase |
1111 | CHEK1; checkpoint kinase 1 |
7157 | TP53; tumor protein p53 |
1026 | CDKN1A; cyclin dependent kinase inhibitor 1A |
983 | CDK1; cyclin dependent kinase 1 |
|
Reference |
|
Authors |
Shaltiel IA, Krenning L, Bruinsma W, Medema RH |
Title |
The same, only different - DNA damage checkpoints and their reversal throughout the cell cycle. |
Journal |
|
Reference |
|
Authors |
Nascimento R, Costa H, Parkhouse RM |
Title |
Virus manipulation of cell cycle. |
Journal |
|
Reference |
|
Authors |
Wang Y, Ji P, Liu J, Broaddus RR, Xue F, Zhang W |
Title |
Centrosome-associated regulators of the G(2)/M checkpoint as targets for cancer therapy. |
Journal |
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LinkDB |
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