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NETWORK: N01682

Entry

N01682                      Network

Name

Blood group A antigen type 4 (Globo-A) biosynthesis

Definition

TypeIVH(Globo-H) -- ABO*A -> TypeIVA(Globo-A)

Expanded

G00099 -- 28v1 -> G00474

Class

nt06035 Blood group carbohydrate antigen biosynthesis

Type

Reference

Pathway

hsa00603

Glycosphingolipid biosynthesis - globo and isoglobo series

Gene

28	ABO; ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase

Variant

28v1 (ABO*A) ABO A allele

Metabolite

G00099

Globo-H

G00474

Globo-A

Reference

PMID:3944092

Authors

Clausen H, Holmes E, Hakomori S

Title

Novel blood group H glycolipid antigens exclusively expressed in blood group A and AB erythrocytes (type 3 chain H). II. Differential conversion of different H substrates by A1 and A2 enzymes, and type 3 chain H expression in relation to secretor status.

Journal

J Biol Chem 261:1388-92 (1986)

LinkDB

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