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KEGG   REACTION: R08268
Entry
R08268                      Reaction                               
Definition
Tamoxifen <=> N-Desmethyltamoxifen
Equation
Comment
CYP3A4: N-demethylation
incomplete reaction
Reaction class
RC00181  C07108_C16546
Enzyme
1.14.14.-
Pathway
rn00982  Drug metabolism - cytochrome P450
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.-
     R08268  Tamoxifen <=> N-Desmethyltamoxifen
Orthology
K17689  cytochrome P450 family 3 subfamily A4 [EC:1.14.13.32 1.14.14.55 1.14.14.56 1.14.14.57 1.14.14.73 1.14.14.-]
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