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REACTION: R08629
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Entry
R08629 Reaction
Name
3-(4'-methylthio)butylmalate:NAD+ oxidoreductase (decarboxylating)
Definition
3-(4'-Methylthio)butylmalic acid + NAD+ <=> 2-Oxo-7-methylthioheptanoic acid + CO2 + NADH + H+
Equation
C17219
+
C00003
<=>
C17220
+
C00011
+
C00004
+
C00080
Comment
two-step reaction (similar to
R10052, R04426+R01652
)
Reaction class
RC00114
C17219_C17220
Enzyme
1.1.1.-
Pathway
rn00966
Glucosinolate biosynthesis
rn01210
2-Oxocarboxylic acid metabolism
Brite
Enzymatic reactions [BR:
br08201
]
1. Oxidoreductase reactions
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.-
R08629 3-(4'-Methylthio)butylmalic acid + NAD+ <=> 2-Oxo-7-methylthioheptanoic acid + CO2 + NADH + H+
BRITE hierarchy
Orthology
K21360
3-isopropylmalate/methylthioalkylmalate dehydrogenase [EC:
1.1.1.85
1.1.1.-]
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