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Antechinus flavipes (yellow-footed antechinus): 127555440
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Entry
127555440 CDS
T08818
Name
(RefSeq) tyrosine-protein kinase JAK2 isoform X1
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
afz
Antechinus flavipes (yellow-footed antechinus)
Pathway
afz01521
EGFR tyrosine kinase inhibitor resistance
afz04062
Chemokine signaling pathway
afz04148
Efferocytosis
afz04151
PI3K-Akt signaling pathway
afz04217
Necroptosis
afz04550
Signaling pathways regulating pluripotency of stem cells
afz04630
JAK-STAT signaling pathway
afz04658
Th1 and Th2 cell differentiation
afz04659
Th17 cell differentiation
afz04725
Cholinergic synapse
afz04917
Prolactin signaling pathway
afz04920
Adipocytokine signaling pathway
afz04933
AGE-RAGE signaling pathway in diabetic complications
afz04935
Growth hormone synthesis, secretion and action
afz05140
Leishmaniasis
afz05145
Toxoplasmosis
afz05152
Tuberculosis
afz05161
Hepatitis B
afz05164
Influenza A
afz05167
Kaposi sarcoma-associated herpesvirus infection
afz05168
Herpes simplex virus 1 infection
afz05200
Pathways in cancer
afz05207
Chemical carcinogenesis - receptor activation
afz05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
afz05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
afz00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
127555440
04151 PI3K-Akt signaling pathway
127555440
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
127555440
09143 Cell growth and death
04217 Necroptosis
127555440
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
127555440
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
127555440
04659 Th17 cell differentiation
127555440
04062 Chemokine signaling pathway
127555440
09152 Endocrine system
04920 Adipocytokine signaling pathway
127555440
04917 Prolactin signaling pathway
127555440
04935 Growth hormone synthesis, secretion and action
127555440
09156 Nervous system
04725 Cholinergic synapse
127555440
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
127555440
05207 Chemical carcinogenesis - receptor activation
127555440
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
127555440
09172 Infectious disease: viral
05161 Hepatitis B
127555440
05164 Influenza A
127555440
05168 Herpes simplex virus 1 infection
127555440
05167 Kaposi sarcoma-associated herpesvirus infection
127555440
09171 Infectious disease: bacterial
05152 Tuberculosis
127555440
09174 Infectious disease: parasitic
05145 Toxoplasmosis
127555440
05140 Leishmaniasis
127555440
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
127555440
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
127555440
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
127555440
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
afz01001
]
127555440
Enzymes [BR:
afz01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
127555440
Protein kinases [BR:
afz01001
]
Non-receptor tyrosine kinases
JAK family [OT]
127555440
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
ABC1
FERM_C_FAK1
Kinase-like
RIO1
Motif
Other DBs
NCBI-GeneID:
127555440
NCBI-ProteinID:
XP_051843695
LinkDB
All DBs
Position
1:complement(110086330..110244783)
Genome browser
AA seq
1130 aa
AA seq
DB search
MACLTMTEMEESAISSTHQNGDIPGNDDTLKQIEPIFQVYLYHSLGKTEGDYLQFPVGEY
IAEEICIAACKACGITPVYHNMFALMSETERIWYPPNHVFHVDEATRYNVLYRIRFYFPH
WYCNGGNRTYRYGISRGAEAPLLDDFVMSYLFAQWRDDFVHGWIKVPVTHETQEECLGMA
VLDIMRIAKEKDQTPLAVYNSTSYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQQFSQ
CKATARILKLKYLINLETLQSAFYSEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSRGK
HKDSETLTEQDLQMYCDFPDIIDVSIKQANQEGSNENRVVTIHKQDSKNLEIEFRSLREA
LSFVSLIDGYYRLTADAHHYLCKEVAPPTVLENIQSNCHGPISMDFAISKLKKAGNQTGL
YVLRCSPKDFNTYFLTFAVERENITDYKHCLITKNENGEFNLSGTKKNFTNLKDLLNCYQ
METVRSDNIIFQFIKCCPPKPKDKSNLLVFRSNGISDVPTSPTFQRHNNVNQMVFHKIRN
EDLIFNESLGQGTFTKIFKGVRREIGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMS
QLSYKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLEVAKQLAWAMH
FLEEKSLTHGNVCTKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPE
CIDNPKNLSLAADKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTELAN
LINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNVRFGALGFSGAFEDRDPT
QFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEIL
KSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERLDHKKLLQYTSQICK
GMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYA
PESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELL
KNNGRLPRPDGCPDEIYSIMTECWNNNVSLRPAFRDLALRVDQIRDDMGG
NT seq
3393 nt
NT seq
+upstream
nt +downstream
nt
atggcttgcctcaccatgacagaaatggaggaatctgccatatcttctacccaccaaaat
ggagatattcctgggaacgatgatactttgaagcagattgagccaatttttcaggtctat
ctttaccactctcttgggaagactgaaggagattatttacagtttccagttggggaatat
attgctgaggaaatttgtattgctgcttgtaaagcttgtggtatcacccctgtctatcat
aatatgtttgctttaatgagtgaaactgagaggatctggtatcctcccaaccatgtcttc
catgtggatgaggcaaccagatacaatgtactctaccgaataaggttttactttcctcat
tggtattgtaatggaggtaatagaacataccggtatggaatatctcgaggtgcagaagcc
cctcttcttgatgactttgtcatgtcttacctttttgctcagtggcgggatgattttgtt
catggatggatcaaagtacctgtgactcatgaaacacaagaagaatgtcttggaatggct
gtcttagatataatgagaatagctaaagaaaaggatcagaccccactggcagtctataac
tctaccagctacaagaccttcttaccaaaatgtgttcgagcaaagatccaagattatcat
attttgacacgaaagcgaataaggtacagattccgcagatttattcagcagttcagccaa
tgcaaagctactgccagaatcttgaaacttaaatatcttataaatctggaaactcttcag
tctgccttctactcagagcaatttgaagtaaaagaacctggcagaggtccttcaggtgag
gagatttttgcaaccattataataactggaaacggtggaattcaatggtcacgagggaaa
cataaagacagtgagaccctgacagaacaggatttacagatgtattgtgactttcctgat
attattgatgtcagcattaagcaagcaaatcaagaaggttcaaatgagaacagagtggtg
actatccataagcaggatagcaaaaatttggaaattgaatttcgttcattgagagaagcg
ctatcttttgtatccttaattgatggatactatagattaactgcagatgcacaccattac
ctttgtaaagaagtagctcctccaacagtccttgaaaatattcaaagcaactgtcatggt
ccaatttcgatggattttgccataagtaaactgaagaaagcaggtaatcagactggactc
tatgtccttcgatgtagccccaaggactttaatacatattttctcacttttgccgttgag
cgagaaaatatcactgattataagcactgtttgattacaaaaaatgagaatggagagttc
aacctcagtgggactaaaaagaacttcactaatcttaaggacctcttgaattgctatcag
atggaaactgtccgctcagataacatcattttccagtttattaagtgttgccccccaaag
cccaaagataaatcaaatcttctagtcttcaggagtaatggcatttctgatgttcccaca
tcaccaacatttcagaggcataataatgtgaaccaaatggtgtttcataaaatcagaaat
gaagatttaatatttaatgaaagccttgggcaaggcacttttaccaagatttttaaaggt
gtaagaagagaaataggagactatggtcagctccatgaaacagaagtccttttaaaagtt
ctggataaagcacatagaaattattcagagtctttttttgaagcagcaagcatgatgagc
cagctttcttacaagcatctggtattaaattatggagtctgtgtctgcggagaagagaat
attctagttcaagaatttgtgaaatttggatcattggacacataccttaaaaagaacaaa
aattctataaacatattatggaagcttgaagtggccaaacaattggcatgggctatgcat
tttcttgaagaaaaaagcctcactcatggtaatgtgtgtactaagaacattttgctaatc
agagaagaggacagaaagacaggaaatcctcctttcatcaagctcagtgatcctggcatt
agtattacagttttgccaaaagacattcttcaagagaggataccatgggtcccacctgaa
tgtattgacaatcctaagaatctaagtttggcagcagataagtggagttttggtaccact
ttgtgggaaatctgcagtggaggagacaaacctctgagtgcattagattctcaaagaaaa
cttcagttctatgaagatagacaccagctccctgcaccaaagtggacagaattagcaaat
cttataaataattgtatggactatgagccagacttcagaccttctttccgggccatcata
cgagaccttaacagcttattcactccagactatgaactactaacagaaaatgacatgttg
ccaaatgtgagatttggtgccctaggattttctggtgcttttgaagacagagatcccaca
cagtttgaagaaagacatcttaaattcctacagcaacttggcaagggtaattttgggagt
gtggagatgtgccgatatgaccctctacaagacaacactggtgaagtggtggctgtgaaa
aagttacagcacagtactgaggagcacctgagagactttgaaagagaaattgaaattctt
aagtctttacaacatgacaacattgtcaaatacaagggagtgtgctacagtgctggccgt
cgtaacttgaggttaattatggaatatttaccttatggaagtttacgtgattatctccag
aaacataaggaaagactggatcataagaaacttttacagtacacatctcaaatctgcaag
ggaatggagtatcttggtacaaaaagatatatccatagggatctggccacaagaaatatt
ttagtggaaaatgagaatagagttaaaattggagattttggattaacaaaagtcctgcca
caagacaaagaatactacaaagtgaaagaacctggtgaaagtcccatattctggtatgct
ccagaatcactcacagaaagcaagttttctgtagcctcagatgtgtggagttttggagtg
gttctgtatgaacttttcacatatattgagaaaagcaaaagcccaccagcggaatttatg
cgtatgattggtaatgacaaacaagggcagatgattgtattccatctaatagaactttta
aagaataatggaaggttgccaagaccagatggatgtcctgatgagatttattctatcatg
actgagtgttggaacaataatgtaagcttacgccctgccttcagggatcttgctcttcga
gtggatcaaataagagatgacatgggtggatga
DBGET
integrated database retrieval system