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Artibeus jamaicensis (Jamaican fruit-eating bat): 119044502
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Entry
119044502 CDS
T07223
Symbol
BRAF
Name
(RefSeq) serine/threonine-protein kinase B-raf isoform X1
KO
K04365
B-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
ajm
Artibeus jamaicensis (Jamaican fruit-eating bat)
Pathway
ajm01521
EGFR tyrosine kinase inhibitor resistance
ajm01522
Endocrine resistance
ajm04010
MAPK signaling pathway
ajm04012
ErbB signaling pathway
ajm04015
Rap1 signaling pathway
ajm04024
cAMP signaling pathway
ajm04062
Chemokine signaling pathway
ajm04068
FoxO signaling pathway
ajm04150
mTOR signaling pathway
ajm04270
Vascular smooth muscle contraction
ajm04510
Focal adhesion
ajm04650
Natural killer cell mediated cytotoxicity
ajm04720
Long-term potentiation
ajm04722
Neurotrophin signaling pathway
ajm04726
Serotonergic synapse
ajm04730
Long-term depression
ajm04810
Regulation of actin cytoskeleton
ajm04910
Insulin signaling pathway
ajm04914
Progesterone-mediated oocyte maturation
ajm04928
Parathyroid hormone synthesis, secretion and action
ajm04934
Cushing syndrome
ajm05010
Alzheimer disease
ajm05022
Pathways of neurodegeneration - multiple diseases
ajm05034
Alcoholism
ajm05160
Hepatitis C
ajm05161
Hepatitis B
ajm05200
Pathways in cancer
ajm05205
Proteoglycans in cancer
ajm05208
Chemical carcinogenesis - reactive oxygen species
ajm05210
Colorectal cancer
ajm05211
Renal cell carcinoma
ajm05212
Pancreatic cancer
ajm05213
Endometrial cancer
ajm05214
Glioma
ajm05215
Prostate cancer
ajm05216
Thyroid cancer
ajm05218
Melanoma
ajm05219
Bladder cancer
ajm05220
Chronic myeloid leukemia
ajm05221
Acute myeloid leukemia
ajm05223
Non-small cell lung cancer
ajm05224
Breast cancer
ajm05225
Hepatocellular carcinoma
ajm05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
ajm00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
119044502 (BRAF)
04012 ErbB signaling pathway
119044502 (BRAF)
04015 Rap1 signaling pathway
119044502 (BRAF)
04068 FoxO signaling pathway
119044502 (BRAF)
04024 cAMP signaling pathway
119044502 (BRAF)
04150 mTOR signaling pathway
119044502 (BRAF)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
119044502 (BRAF)
09142 Cell motility
04810 Regulation of actin cytoskeleton
119044502 (BRAF)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
119044502 (BRAF)
04062 Chemokine signaling pathway
119044502 (BRAF)
09152 Endocrine system
04910 Insulin signaling pathway
119044502 (BRAF)
04914 Progesterone-mediated oocyte maturation
119044502 (BRAF)
04928 Parathyroid hormone synthesis, secretion and action
119044502 (BRAF)
09153 Circulatory system
04270 Vascular smooth muscle contraction
119044502 (BRAF)
09156 Nervous system
04726 Serotonergic synapse
119044502 (BRAF)
04720 Long-term potentiation
119044502 (BRAF)
04730 Long-term depression
119044502 (BRAF)
04722 Neurotrophin signaling pathway
119044502 (BRAF)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
119044502 (BRAF)
05205 Proteoglycans in cancer
119044502 (BRAF)
05208 Chemical carcinogenesis - reactive oxygen species
119044502 (BRAF)
09162 Cancer: specific types
05210 Colorectal cancer
119044502 (BRAF)
05212 Pancreatic cancer
119044502 (BRAF)
05225 Hepatocellular carcinoma
119044502 (BRAF)
05226 Gastric cancer
119044502 (BRAF)
05214 Glioma
119044502 (BRAF)
05216 Thyroid cancer
119044502 (BRAF)
05221 Acute myeloid leukemia
119044502 (BRAF)
05220 Chronic myeloid leukemia
119044502 (BRAF)
05218 Melanoma
119044502 (BRAF)
05211 Renal cell carcinoma
119044502 (BRAF)
05219 Bladder cancer
119044502 (BRAF)
05215 Prostate cancer
119044502 (BRAF)
05213 Endometrial cancer
119044502 (BRAF)
05224 Breast cancer
119044502 (BRAF)
05223 Non-small cell lung cancer
119044502 (BRAF)
09172 Infectious disease: viral
05161 Hepatitis B
119044502 (BRAF)
05160 Hepatitis C
119044502 (BRAF)
09164 Neurodegenerative disease
05010 Alzheimer disease
119044502 (BRAF)
05022 Pathways of neurodegeneration - multiple diseases
119044502 (BRAF)
09165 Substance dependence
05034 Alcoholism
119044502 (BRAF)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
119044502 (BRAF)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
119044502 (BRAF)
01522 Endocrine resistance
119044502 (BRAF)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ajm01001
]
119044502 (BRAF)
Enzymes [BR:
ajm01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
119044502 (BRAF)
Protein kinases [BR:
ajm01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
119044502 (BRAF)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
ABC1
C1_2
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
119044502
NCBI-ProteinID:
XP_036994752
LinkDB
All DBs
Position
Unknown
AA seq
763 aa
AA seq
DB search
MAALSGDGGAEQGQALFNGDMEPEAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEAL
LDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLGNGTDFSVSSSASTDTVTSSS
SSSLSVLPSSLSVFQSPTDVSRSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKA
LMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFT
LAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEE
ASLAETSLASGSSPSVPPSDSIGPQILTTPSPSKSIPIPQPFRPADEDHRNQFGQRDRSS
SAPNVHINTIEPVNIDDLIRDQGFRSDGGSTTGLSATPPASLPGSLTNVKALQKSPGPQR
ERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKM
LNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHII
ETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRW
SGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQ
IIFMVGRGYLAPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKI
HRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGEFAAFK
NT seq
2292 nt
NT seq
+upstream
nt +downstream
nt
atggcggcgctgagcggcgacggaggcgcggagcagggccaggctctgttcaacggggac
atggagcccgaggccggcgcgggcgccgcggcctcttctgcggcagaccccgccatcccg
gaggaggtatggaatatcaaacaaatgattaaattgacacaagaacatatagaggcacta
ctggacaaatttggtggagagcataatccaccatcaatatacctggaggcctatgaagaa
tacaccagcaagctagacgccctccagcaaagagaacaacagttactggaatccctgggg
aatggaactgatttttctgtttctagctctgcatcaacggacaccgttacatcttcttcc
tcctctagcctttcagtgctaccttcatctctttcagtttttcaaagtcccacagatgtg
tcacggagcaaccctaagtcaccacagaaacctattgttagagtcttcctgcccaacaaa
cagaggacagtggtacctgcaaggtgtggagtcacagtccgggacagtctgaagaaggcc
ctgatgatgagaggtctgatcccagagtgctgcgctgtttacaggattcaggatggagag
aagaagccaattggctgggacactgatatctcctggcttactggagaggaattgcatgtg
gaagtattggagaatgttccgcttacaacacacaacttcgtacggaaaacatttttcacc
ttagcattttgtgacttttgccgaaagctgcttttccagggtttccgttgtcaaacatgt
ggttataaatttcaccagcgttgtagtaccgaggttccactgatgtgtgttaattatgac
caacttgatttgctgtttgtctccaagttttttgaacaccatccaataccacaggaggag
gcctccttagcagaaacttcccttgcatctggatcatccccttccgtacccccctccgat
tctattgggccccaaatcctcaccactccgtctccttcaaaatccattccaattccacag
cctttccgaccagcagatgaagatcaccgaaatcagtttggacaacgagaccggtcttca
tcagctccaaatgtgcatataaatacaatagaacctgtcaatatcgatgacttgattaga
gaccaagggtttcgtagtgatggaggatcaactacaggtttatctgccacccctcctgcc
tcattacctggctcactcactaatgtgaaagcgttacagaagtctccaggacctcagagg
gagagaaaatcatcttcatcctcggaagacaggaatcgaatgaaaacacttggtagacgg
gattcaagtgatgactgggagattcccgatgggcagatcacagtgggacagagaattgga
tctgggtcgtttggaacagtctacaagggaaagtggcacggtgatgtggcggtgaaaatg
ttgaatgtgacagcacccacacctcaacagttacaagccttcaaaaatgaagtaggagta
ctcaggaaaactcgacatgtgaatattctactcttcatgggctattcaacaaagccacag
ctggctattgtcacccagtggtgtgagggctccagcttatatcaccatctccacatcatt
gagaccaaatttgagatgatcaaacttatagatatcgcacgacagactgcacagggcatg
gattacttacacgccaagtcaatcatccacagagacctcaagagtaataatatttttctt
catgaagacctcacagtaaaaataggtgactttggtctagccacagtgaaatctcgatgg
agtgggtcccatcagtttgagcagttgtctggatccattttgtggatggctccagaagta
atcagaatgcaagataaaaacccatatagctttcagtcagatgtatatgcatttgggatt
gttctgtatgaattgatgactggacagttaccttattcaaacatcaacaacagggaccag
ataatttttatggtgggacgaggatacctagctccagacctcagtaaggtacgaagtaac
tgtccaaaagccatgaagagattaatggcggagtgcctaaaaaagaaaagagatgagaga
ccactctttccccaaatcctcgcctctattgagctgctggcccgctcattgccaaaaatt
caccgcagtgcatcagaaccctccttgaatcgggctggcttccagacagaggatttcagt
ctctatgcttgtgcttctccgaaaacgcccatccaggcagggggatacggagaatttgca
gccttcaagtag
DBGET
integrated database retrieval system