Svoboda
|
Graniru
|
BBC Russia
|
Golosameriki
|
Facebook
Bos mutus (wild yak): 102278692
Help
Entry
102278692 CDS
T02919
Symbol
JAK2
Name
(RefSeq) Janus kinase 2
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
bom
Bos mutus (wild yak)
Pathway
bom01521
EGFR tyrosine kinase inhibitor resistance
bom04062
Chemokine signaling pathway
bom04148
Efferocytosis
bom04151
PI3K-Akt signaling pathway
bom04217
Necroptosis
bom04550
Signaling pathways regulating pluripotency of stem cells
bom04630
JAK-STAT signaling pathway
bom04658
Th1 and Th2 cell differentiation
bom04659
Th17 cell differentiation
bom04725
Cholinergic synapse
bom04917
Prolactin signaling pathway
bom04920
Adipocytokine signaling pathway
bom04933
AGE-RAGE signaling pathway in diabetic complications
bom04935
Growth hormone synthesis, secretion and action
bom05140
Leishmaniasis
bom05145
Toxoplasmosis
bom05152
Tuberculosis
bom05161
Hepatitis B
bom05164
Influenza A
bom05167
Kaposi sarcoma-associated herpesvirus infection
bom05168
Herpes simplex virus 1 infection
bom05200
Pathways in cancer
bom05207
Chemical carcinogenesis - receptor activation
bom05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
bom05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
bom00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
102278692 (JAK2)
04151 PI3K-Akt signaling pathway
102278692 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
102278692 (JAK2)
09143 Cell growth and death
04217 Necroptosis
102278692 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
102278692 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
102278692 (JAK2)
04659 Th17 cell differentiation
102278692 (JAK2)
04062 Chemokine signaling pathway
102278692 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
102278692 (JAK2)
04917 Prolactin signaling pathway
102278692 (JAK2)
04935 Growth hormone synthesis, secretion and action
102278692 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
102278692 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102278692 (JAK2)
05207 Chemical carcinogenesis - receptor activation
102278692 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
102278692 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
102278692 (JAK2)
05164 Influenza A
102278692 (JAK2)
05168 Herpes simplex virus 1 infection
102278692 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
102278692 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
102278692 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
102278692 (JAK2)
05140 Leishmaniasis
102278692 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
102278692 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
102278692 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102278692 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
bom01001
]
102278692 (JAK2)
Enzymes [BR:
bom01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
102278692 (JAK2)
Protein kinases [BR:
bom01001
]
Non-receptor tyrosine kinases
JAK family [OT]
102278692 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
102278692
NCBI-ProteinID:
XP_005891424
UniProt:
L8IT24
LinkDB
All DBs
Position
Un
AA seq
1132 aa
AA seq
DB search
MGMACLTMTEMEGTSTSPVHQNGDISGNANSVKQIDPVLQVYLYHSLGNAEGDYLQFLTG
EYVAEEICIAASKACGITPVYHSMFALMSETERIWYPPNHVFHIDESTRQNVLYRIRFYF
PYWYCNGSNRTYRHGIARGAEAPLLDDFVMSYLFAQWRHDFLHGWIKVPVTHETQEECLG
MAVLDMMRIAKEKNQTPLDIYSSISYKTFLPKCVRAKIQEYHILTRKRIRYRFRRFIEQF
SHCKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSR
GKHKESETLTEQDLQLYCDFPDIIDISIKQANQEGANESRIVTIHKQDGKSLEIELKSLR
EALSFVSLIDGYYRLTADAHHYLCKEVAPPMVLENIQSNCHGPISMDFAISKLKKTGNQT
GLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENGEYNLSGTKKNFSNLKDLLNC
YQMETVRSDSIIFQFTKCCPPKPKDKSNLLVFRTNGISDVPTSPTLQRHNNVNQMVFHKI
RNEDLVFNESLGQGTFTKIFKGIRREIGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM
MSQLSHKHLILNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLEVAKQLAWA
MHFLEEKTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVP
PECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTEL
ANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRD
PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE
ILKSLQHDNIVKYKGVCYSAGRHNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQI
CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFW
YAPESLTESKFSVASDVWSFGVVLYELFTYIDKSKSPPAEFMRMIGNDKQGQMIVFHLIE
LLKNNGRLPRPDGCPDEIYVIMTECWNNNVNQRPSFRDLAVRVDQIRDNMTG
NT seq
3399 nt
NT seq
+upstream
nt +downstream
nt
atgggaatggcttgccttacaatgacagaaatggaaggaacatccacatcccctgtacat
cagaatggtgatatttctggaaatgctaactctgtgaagcaaatagatccagtcctacag
gtctatctttatcattcccttgggaacgctgagggggattatctgcagtttctaactgga
gagtatgttgctgaagagatctgtattgctgcttctaaagcttgtggaatcacacctgta
tatcacagtatgtttgctttaatgagtgaaacagaaaggatctggtatccacccaaccat
gtcttccatatagatgaatcaaccaggcaaaacgtactctacagaatcagattttacttc
ccttactggtattgtaatggcagcaacagaacctatcgacatggaatagctcgaggtgct
gaagctcctcttcttgatgactttgtcatgtcttacctttttgctcagtggcggcatgat
tttttacatggatggataaaagtacctgtgactcatgaaacacaggaagaatgtcttggg
atggcagtgttagatatgatgagaatagccaaagaaaagaatcaaaccccactggacatc
tatagctctatcagctacaagacatttttgccaaaatgtgttcgagcaaagatccaagag
tatcatattttgacaaggaagagaataaggtacagatttcgcagatttattgagcaattc
agccattgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaact
cttcagtctgccttctacacagagcaatttgaagtaaaagaacctggaagaggtccttca
ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga
gggaaacataaagaaagtgagacactgacagaacaggatttacagttgtattgtgatttt
cctgatattattgatatcagtattaaacaagcaaatcaagaaggcgcaaatgaaagcaga
attgtaactattcataagcaagatggtaaaagtctagaaattgagcttaagtcattaaga
gaagctttgtcttttgtgtcattaattgatggatattatagattaactgcagatgcacat
cattatctttgtaaagaagtagcacctccaatggtgcttgaaaatatacaaagcaactgt
catggcccaatttcaatggattttgctatcagtaaactgaagaaaacaggtaatcagact
ggactctatgtacttcgatgcagtcctaaggactttaataaatattttctgacttttgct
gttgagcgagaaaatgttattgaatataagcactgtttgattaccaaaaatgagaatgga
gaatacaacctcagtggtactaagaagaacttcagtaatcttaaagatcttctgaattgc
taccagatggaaactgttcgctcagacagtataattttccagtttactaaatgctgtccc
ccaaagccaaaagacaaatcaaaccttctagtcttcagaaccaatggtatttctgatgta
ccaacctcaccaactttacaaaggcataataatgtgaaccaaatggtgttccacaaaatt
agaaatgaagatttggtatttaatgaaagccttggccaaggaacttttacaaaaattttt
aaaggtataagaagagaaataggagactatggtcagcttcatgaaacagaagttctttta
aaagttctggataaagcacatagaaactattcagagtctttctttgaagcagcaagcatg
atgagccagctttctcacaaacatctgattttaaattatggagtatgtgtctgtggagag
gagaatattctggttcaggaatttgtaaaatttggatcactagatacgtatctgaaaaag
aataaaaattctataaatatattatggaaacttgaagtggctaaacagttggcatgggcc
atgcattttctagaagaaaaaacccttattcatgggaatgtgtgcgccaaaaatattctt
cttatcagagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgatcct
ggcattagtattacagttttgccaaaagacatcctgcaggagagaataccatgggtacca
cctgaatgcattgaaaatcctaaaaatctaaacctggcaacagacaaatggagttttggt
accacattgtgggaaatctgcagtggaggagataagcctctgagtgctttggattctcaa
agaaaactacagttttatgaagataggcaccagcttcctgcgccaaagtggacagaatta
gcaaatcttattaataattgcatggattatgaaccagattttaggccttctttcagagcc
attataagagatcttaatagtttgtttactccagattatgaactattaacagaaaatgac
atgttaccaaatatgagaataggtgctctaggattttctggtgcttttgaagaccgagac
cctacacaatttgaagaaagacacttgaaatttctacagcaacttggcaagggtaatttt
gggagtgtggagatgtgtcggtatgaccctctacaagacaatactggggaggtggtggct
gtgaaaaagctccagcacagtactgaagagcacctcagagacttcgaaagagaaattgaa
atccttaaatccttgcagcatgacaacattgtaaagtacaaaggagtctgctacagtgct
ggccggcataatctaagattaattatggagtatttaccatatggaagtttacgagactat
ctccaaaaacataaagaacggatagatcataaaaaacttctgcaatacacatctcagata
tgcaaggggatggaatatcttggtacaaaaagatatatccacagggatctggcaacaagg
aatatattagtggagaatgaaaacagagttaaaataggagattttggattaaccaaagtc
ttgccacaagacaaagagtactacaaagtgaaagagcctggtgaaagtcccatattctgg
tatgcaccagaatcactgacagagagcaagttttctgtggcttcagatgtttggagcttt
ggagtggttctgtatgaacttttcacatatattgacaagagtaaaagcccaccagcggaa
tttatgcgtatgattggcaatgacaaacaaggacagatgattgtgttccatttgatagaa
ctcctgaagaataacggaagattaccaagaccagatggatgcccagatgagatatatgtg
attatgacagaatgctggaacaataatgtaaaccagcgcccctctttcagagacctagca
gttcgagttgatcaaataagggacaacatgactggatga
DBGET
integrated database retrieval system