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Cervus canadensis (wapiti): 122452858
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Entry
122452858 CDS
T07554
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2 isoform X1
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
ccad
Cervus canadensis (wapiti)
Pathway
ccad01521
EGFR tyrosine kinase inhibitor resistance
ccad04062
Chemokine signaling pathway
ccad04148
Efferocytosis
ccad04151
PI3K-Akt signaling pathway
ccad04217
Necroptosis
ccad04550
Signaling pathways regulating pluripotency of stem cells
ccad04630
JAK-STAT signaling pathway
ccad04658
Th1 and Th2 cell differentiation
ccad04659
Th17 cell differentiation
ccad04725
Cholinergic synapse
ccad04917
Prolactin signaling pathway
ccad04920
Adipocytokine signaling pathway
ccad04933
AGE-RAGE signaling pathway in diabetic complications
ccad04935
Growth hormone synthesis, secretion and action
ccad05140
Leishmaniasis
ccad05145
Toxoplasmosis
ccad05152
Tuberculosis
ccad05161
Hepatitis B
ccad05164
Influenza A
ccad05167
Kaposi sarcoma-associated herpesvirus infection
ccad05168
Herpes simplex virus 1 infection
ccad05200
Pathways in cancer
ccad05207
Chemical carcinogenesis - receptor activation
ccad05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
ccad05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ccad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
122452858 (JAK2)
04151 PI3K-Akt signaling pathway
122452858 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
122452858 (JAK2)
09143 Cell growth and death
04217 Necroptosis
122452858 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
122452858 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
122452858 (JAK2)
04659 Th17 cell differentiation
122452858 (JAK2)
04062 Chemokine signaling pathway
122452858 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
122452858 (JAK2)
04917 Prolactin signaling pathway
122452858 (JAK2)
04935 Growth hormone synthesis, secretion and action
122452858 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
122452858 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
122452858 (JAK2)
05207 Chemical carcinogenesis - receptor activation
122452858 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
122452858 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
122452858 (JAK2)
05164 Influenza A
122452858 (JAK2)
05168 Herpes simplex virus 1 infection
122452858 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
122452858 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
122452858 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
122452858 (JAK2)
05140 Leishmaniasis
122452858 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
122452858 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
122452858 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
122452858 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ccad01001
]
122452858 (JAK2)
Enzymes [BR:
ccad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
122452858 (JAK2)
Protein kinases [BR:
ccad01001
]
Non-receptor tyrosine kinases
JAK family [OT]
122452858 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
122452858
NCBI-ProteinID:
XP_043342535
LinkDB
All DBs
Position
14:32631461..32746875
Genome browser
AA seq
1132 aa
AA seq
DB search
MGMACLTMTEMEEASTSPVHQNGDISGNASSVKQIDPVLQVYLYHSLGKAEGDYLKFPTG
EYVAEEICVAASKACGITPVYHSMFALMSETERIWYPPNHVFHIDESTRQNVLYRIRFYF
PYWYCNGSNRTYRHGISRGAEAPLLDDFVMSYLFAQWRHDFLHGWIKVPVTHETQEECLG
MAVLDMMRIAKEKNQTPLDIYSSISYKTFLPKCVRAKIQEYHILTRKRIRYRFRRFIEQF
SHCKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSR
GKHKESETLTEQDLQLYCDFPDIIDISIKQANQEGSNESRIVTIHKQDGKSLEIELKSLR
EALSFVSLIDGYYRLTADAHHYLCKEVAPPMVLENIQSNCHGPISMDFAISKLKKTGNQT
GLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENGEYNLSGTKKNFSNLKDLLNC
YQMETVRSDSIIFQFTKCCPPKPKDKSNLLVFRTNGISDVPTSPTLQRHNNVNQMVFHKI
RNEDLVFNESLGQGTFTKIFKGIRREIGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM
MSQLSHKHLILNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLEVAKQLAWA
MHFLEEKTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVP
PECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTEL
ANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRD
PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE
ILKSLQHDNIVKYKGVCYSAGRHNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQI
CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFW
YAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIE
LLKNNGRLPRPDGCPDEIYVIMTECWNNNVSQRPSFRDLAVRVDQIRDNMTG
NT seq
3399 nt
NT seq
+upstream
nt +downstream
nt
atgggaatggcttgccttacaatgacagaaatggaagaagcatccacatcccctgtacat
cagaatggtgatatttctggaaatgctagttctgtgaagcaaatagatccagtcctacag
gtctatctttatcattcccttgggaaagctgagggggattatctgaagtttccaactgga
gagtatgttgctgaagagatttgtgttgctgcttctaaagcttgtggaatcacacctgtg
tatcatagtatgtttgctttaatgagtgaaacagaaaggatctggtatccacccaaccat
gtcttccatatagatgaatcaaccaggcaaaatgtactctacagaatcagattttacttt
ccttactggtattgtaatggcagcaacagaacctatcgacatggaatatctcgaggtgct
gaagctcctcttcttgatgactttgtcatgtcttacctttttgctcagtggcggcatgat
tttttacatggatggataaaagtacctgtgactcatgaaacacaggaagaatgtcttggg
atggcagtgttagatatgatgagaatagccaaagaaaagaatcaaaccccactggacatc
tatagctctatcagctacaagacatttttgccaaaatgtgttcgagcaaagatccaagag
tatcatattttgacaaggaagagaataaggtacagatttcgcagatttattgagcaattc
agccattgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaact
cttcagtctgccttctacacagagcagtttgaagtaaaagaacctggaagaggtccttca
ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga
gggaaacataaagaaagtgagacactgacagaacaggatttacagttgtattgtgatttt
cctgatattattgatatcagtattaaacaagcaaatcaagaaggctcaaatgaaagcaga
attgtaactattcataagcaggatggtaaaagtctagaaattgagcttaagtcattaaga
gaagctttgtcttttgtgtcattaattgatggatattatagattaactgcagatgcacat
cattatctttgtaaagaagtagcacctccaatggtgcttgaaaatatacaaagcaactgt
catggcccaatttcaatggattttgctatcagtaaactgaagaaaacaggtaatcagact
ggactctatgtacttcgatgcagtcctaaggactttaataaatattttctgacttttgct
gttgagcgagaaaatgtaattgaatataagcactgtttgattacgaaaaatgagaatgga
gaatacaacctcagtggtactaagaagaacttcagtaatcttaaagatcttctgaattgc
taccagatggaaactgttcgctcggacagtataattttccaatttactaaatgctgtccc
ccaaagccaaaagacaaatcaaaccttctagtcttcagaaccaatggtatttctgatgta
ccaacctcaccaactttacaaaggcataataatgtgaaccaaatggtgttccacaaaatt
agaaatgaagatttggtatttaatgaaagccttggccaaggaacttttacaaaaattttt
aaaggtataagaagagaaataggagactatggtcagctgcatgaaacagaagttctttta
aaagttctggataaagcgcatagaaactattcagagtctttctttgaagcagcaagcatg
atgagccagctttctcacaaacatctgattttaaattatggagtatgtgtctgtggagag
gagaatattctggttcaggaatttgtaaaatttggatcactagatacatatctgaaaaag
aataaaaattctataaatatattatggaaacttgaagtggctaaacagttggcatgggcc
atgcattttctagaagaaaaaacccttattcatgggaatgtgtgcgccaaaaatattctt
cttatcagagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgatcct
ggcattagtattacagttttgccaaaagacatcctgcaggagagaataccatgggtacca
cctgaatgcattgaaaatcctaaaaatctaaacctggcaacagacaaatggagttttggt
accacattgtgggaaatctgtagtggaggagataagcctctgagtgctttggattctcaa
agaaaactacagttttatgaagataggcaccagcttcctgcaccaaagtggacagaatta
gcaaatcttattaataattgcatggattatgaaccagattttagaccttctttcagagcc
attataagagatcttaatagtttgtttactccagattatgaactattaacagaaaatgac
atgttaccaaatatgagaataggtgccctagggttttctggtgcttttgaagaccgagac
cctacacaatttgaagaaagacacttgaaatttctacagcaacttggcaagggtaatttt
gggagtgtggagatgtgccggtatgaccctctacaagacaatactggggaggtggtggct
gtgaaaaagctccagcacagtactgaagagcacctcagagacttcgaaagagaaattgaa
atccttaaatccttgcagcatgacaacattgtgaagtacaaaggagtctgctacagtgct
ggccggcataatctaagattaattatggagtatttaccatatggaagtttacgagactat
ctccaaaaacataaagaacggatagatcataaaaaacttctgcagtacacatctcagata
tgcaagggtatggagtatcttggtacaaaaaggtatatccacagggatctggcgacaagg
aatatactagtggagaatgaaaacagagttaaaataggagattttggattaaccaaagtc
ttgccacaagacaaagagtactacaaagtgaaagagcctggtgaaagtcccatattctgg
tatgcaccagagtcactgacagagagcaagttttccgtggcctcagatgtttggagcttc
ggagtggttctctatgaactcttcacgtacattgagaagagtaaaagcccgccagcggaa
tttatgcgtatgattggcaatgacaaacaaggacagatgattgtgtttcatttgatagaa
ctcctgaagaataatggaagattaccaagaccagatggatgcccagatgagatttatgtg
attatgacagaatgctggaacaataatgtaagccagcgcccctctttcagagacctagct
gttcgagttgatcaaataagggacaacatgactggatga
DBGET
integrated database retrieval system