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Camelus ferus (Wild Bactrian camel): 102520220
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Entry
102520220 CDS
T02979
Symbol
JAK2
Name
(RefSeq) LOW QUALITY PROTEIN: tyrosine-protein kinase JAK2
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
cfr
Camelus ferus (Wild Bactrian camel)
Pathway
cfr01521
EGFR tyrosine kinase inhibitor resistance
cfr04062
Chemokine signaling pathway
cfr04148
Efferocytosis
cfr04151
PI3K-Akt signaling pathway
cfr04217
Necroptosis
cfr04550
Signaling pathways regulating pluripotency of stem cells
cfr04630
JAK-STAT signaling pathway
cfr04658
Th1 and Th2 cell differentiation
cfr04659
Th17 cell differentiation
cfr04725
Cholinergic synapse
cfr04917
Prolactin signaling pathway
cfr04920
Adipocytokine signaling pathway
cfr04933
AGE-RAGE signaling pathway in diabetic complications
cfr04935
Growth hormone synthesis, secretion and action
cfr05140
Leishmaniasis
cfr05145
Toxoplasmosis
cfr05152
Tuberculosis
cfr05161
Hepatitis B
cfr05164
Influenza A
cfr05167
Kaposi sarcoma-associated herpesvirus infection
cfr05168
Herpes simplex virus 1 infection
cfr05200
Pathways in cancer
cfr05207
Chemical carcinogenesis - receptor activation
cfr05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
cfr05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
cfr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
102520220 (JAK2)
04151 PI3K-Akt signaling pathway
102520220 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
102520220 (JAK2)
09143 Cell growth and death
04217 Necroptosis
102520220 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
102520220 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
102520220 (JAK2)
04659 Th17 cell differentiation
102520220 (JAK2)
04062 Chemokine signaling pathway
102520220 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
102520220 (JAK2)
04917 Prolactin signaling pathway
102520220 (JAK2)
04935 Growth hormone synthesis, secretion and action
102520220 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
102520220 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102520220 (JAK2)
05207 Chemical carcinogenesis - receptor activation
102520220 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
102520220 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
102520220 (JAK2)
05164 Influenza A
102520220 (JAK2)
05168 Herpes simplex virus 1 infection
102520220 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
102520220 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
102520220 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
102520220 (JAK2)
05140 Leishmaniasis
102520220 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
102520220 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
102520220 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102520220 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cfr01001
]
102520220 (JAK2)
Enzymes [BR:
cfr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
102520220 (JAK2)
Protein kinases [BR:
cfr01001
]
Non-receptor tyrosine kinases
JAK family [OT]
102520220 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
102520220
NCBI-ProteinID:
XP_032333619
UniProt:
A0A8B8SUY6
LinkDB
All DBs
Position
4:complement(29545105..29632862)
Genome browser
AA seq
1130 aa
AA seq
DB search
MACLTMTEMEGTSASPIHQNGDIPGNSNSVKEIDPVLQVYLYHSLGKAEGEYLKFPPGEY
VAEEICVAASKACGITPVYHSMFALMSETERIWYPPNHVFHIDESTKHSVLYRIRFYFPY
WYCNGSNRTYRHGISRGAEAPLLDDFVMSYLFAQWRHDFLHGWIKVPVTHETQEECLGMA
VLDMMRIAKEKDQTPLDIYSSISYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIEQFSH
CKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIVITGNGGIQWSRGK
HKESETLTEQGLQLYCDFPDIIDVSIKQANQEGSNESRIVTIHKQDGKSLEIELSSLSEA
LSFVSLIDGYYRLTADAHHYLCKEVAPPMVLENIQSNCHGPISMDFAISKLKKAGNQTGL
YVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENGEYNLSGTKKNFNNLKDLLNCYQ
METVRSDSIIFQFTKCCPPKPKDKSNLLVFRTNGISDIPTSPTLQRHNNVNQMVFHKIRN
EDLMFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMS
QLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLEVAKQLAWAMH
FLEEKTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPE
CIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTELAN
LINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDPT
QFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEIL
KSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLREYLQKHKERIDHKKLLQYTSQICK
GMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYA
PESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELL
KNNGRLPRPDGCPDEIYVIMTECWNNNVNQRPSFRDLAFRVDQIRDNMAG
NT seq
3393 nt
NT seq
+upstream
nt +downstream
nt
atggcttgccttacaatgacagaaatggaaggaacatctgcatcccctatacatcagaat
ggtgatattcctggaaactctaattctgtgaaggaaatagatccagtcctacaggtttat
ctttatcattcccttggaaaagctgagggagagtatctaaagtttccacctggggagtac
gttgcagaagaaatttgtgttgctgcttctaaagcttgtggaatcacacctgtgtatcat
agtatgtttgctttaatgagtgaaacagaaaggatctggtacccacccaaccatgtcttc
catatagatgaatcaaccaagcacagtgtactctacagaatcagattttactttccctac
tggtattgtaatggcagcaacagaacctatcggcatggaatatctcgaggtgctgaagct
cctcttcttgacgactttgtcatgtcttacctttttgctcagtggcggcatgattttttg
catggatggataaaagtacctgtgactcatgaaacacaggaagaatgtcttgggatggcg
gtattagatatgatgagaatagctaaagaaaaggatcaaactccactggacatctatagc
tctatcagctacaagacattcttaccaaaatgtgtccgagcaaagatccaggactatcat
attttgacaaggaagcgaataaggtacagatttcgccgatttattgagcagttcagccat
tgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaactcttcag
tctgccttctacacagagcaatttgaagtaaaagaacctggaagaggtccttcaggtgag
gagatttttgcaaccattgtaataactggaaacggtggaattcagtggtcaagagggaaa
cataaagaaagtgagacactgacagaacagggtttacagttatattgtgattttcctgat
attattgatgtcagtattaaacaagcaaaccaagaaggctcaaatgaaagcagaattgta
actattcataagcaagatggtaaaagtctggaaattgaacttagctcattaagtgaagct
ttgtcttttgtgtctttaattgacggatattatagattaactgcagatgcacatcattat
ctttgtaaagaagtagcacctccaatggtacttgaaaatatacaaagcaactgtcatggc
ccaatttcaatggattttgctatcagtaaactgaagaaagcaggtaatcagactggactt
tatgtacttcgatgcagtcctaaggattttaataaatattttctgacttttgctgttgag
cgagaaaatgtcattgaatataagcactgtttgattacaaaaaatgagaatggagaatac
aacctcagtggtactaagaagaacttcaataatcttaaagatcttttgaattgctaccag
atggaaactgttcgctcagacagtatcatcttccagtttactaaatgctgtcccccaaag
ccaaaagataaatcaaaccttctggtcttcagaaccaatggtatttctgatataccaacc
tcaccaacattacagagacataataatgtgaaccaaatggtgttccacaaaatcagaaat
gaagatttgatgtttaatgaaagccttggccaaggtacttttacaaaaatttttaaaggc
gtaagaagggaagtaggagactacggtcaactgcatgaaacagaagttcttttaaaagtt
ctggataaagcacatagaaactattcagagtctttctttgaagcagcaagcatgatgagc
cagctttctcacaaacatctggttttaaattatggagtatgtgtctgtggagaggagaat
attctggttcaggagtttgtaaaatttggatcactagatacatatctgaaaaagaataaa
aattctataaatatattatggaaacttgaagtggctaaacagttggcgtgggccatgcat
tttctagaagaaaaaacccttattcatggaaatgtgtgtgccaaaaatattcttcttatc
agagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgatcctggcatt
agtattacagttttgccaaaggacattctgcaggagagaataccatgggtaccacctgaa
tgcattgaaaatcctaaaaatctaaacttagcaacagacaaatggagttttggtaccact
ttgtgggaaatctgcagtggaggagataagcctctgagtgctttggattctcaaagaaag
ctacaattttatgaagataggcaccaacttcctgcaccaaagtggacagaattagcaaat
cttattaataattgtatggattatgaaccagattttagaccttctttcagagccatcatt
cgagatcttaacagtttgtttactccagattatgaactattaacagaaaatgacatgtta
ccaaatatgaggataggtgccctagggttttctggtgcttttgaagaccgagaccctaca
caatttgaagagagacacttgaaatttctacagcaacttggcaagggtaattttgggagt
gtggagatgtgccggtatgaccctctacaagacaatactggggaggtggtagctgttaaa
aagctccagcacagtactgaagagcacctcagagactttgaaagggaaattgaaatcctt
aaatccttgcagcatgacaacattgtaaagtacaagggagtgtgctacagtgctggccgg
cgtaatctaagattaattatggaatatttaccatatggaagtttacgagagtatctccaa
aaacataaagaacggatagatcataaaaaacttctgcagtacacatctcagatatgcaag
ggcatggaatatcttggtacaaaaaggtatatccacagagatctggcaacaaggaatata
ttggtggagaatgaaaacagagttaaaataggagattttggtttaaccaaagtcttgcca
caagacaaagaatactacaaggtgaaagaacctggtgaaagtcctatattctggtatgca
ccagaatcactgacagagagcaagttttctgtggcttcagatgtttggagctttggagtg
gttctgtatgaacttttcacatatattgagaaaagtaaaagcccaccagcggaatttatg
cgtatgattggcaatgacaaacaaggacagatgattgtgtttcatttgatagaacttctg
aagaataatggaagattaccaagaccagatggatgcccagacgagatttatgtaatcatg
acagaatgctggaacaataatgtaaatcagcgcccctctttcagagatctagcttttcga
gttgatcaaataagggacaacatggctggatga
DBGET
integrated database retrieval system