Cricetulus griseus (Chinese hamster): 100769337 Help Entry 100769337         CDS       T02813                                  Symbol Jak2 Name (RefSeq) tyrosine-protein kinase JAK2   KO K04447   Janus kinase 2 [EC:2.7.10.2] Organism cge  Cricetulus griseus (Chinese hamster) Pathway cge01521   EGFR tyrosine kinase inhibitor resistance cge04062   Chemokine signaling pathway cge04148   Efferocytosis cge04151   PI3K-Akt signaling pathway cge04217   Necroptosis cge04550   Signaling pathways regulating pluripotency of stem cells cge04630   JAK-STAT signaling pathway cge04658   Th1 and Th2 cell differentiation cge04659   Th17 cell differentiation cge04725   Cholinergic synapse cge04917   Prolactin signaling pathway cge04920   Adipocytokine signaling pathway cge04933   AGE-RAGE signaling pathway in diabetic complications cge04935   Growth hormone synthesis, secretion and action cge05140   Leishmaniasis cge05145   Toxoplasmosis cge05152   Tuberculosis cge05161   Hepatitis B cge05164   Influenza A cge05167   Kaposi sarcoma-associated herpesvirus infection cge05168   Herpes simplex virus 1 infection cge05200   Pathways in cancer cge05207   Chemical carcinogenesis - receptor activation cge05235   PD-L1 expression and PD-1 checkpoint pathway in cancer cge05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:cge00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     100769337 (Jak2)    04151 PI3K-Akt signaling pathway     100769337 (Jak2)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     100769337 (Jak2)   09143 Cell growth and death    04217 Necroptosis     100769337 (Jak2)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     100769337 (Jak2)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     100769337 (Jak2)    04659 Th17 cell differentiation     100769337 (Jak2)    04062 Chemokine signaling pathway     100769337 (Jak2)   09152 Endocrine system    04920 Adipocytokine signaling pathway     100769337 (Jak2)    04917 Prolactin signaling pathway     100769337 (Jak2)    04935 Growth hormone synthesis, secretion and action     100769337 (Jak2)   09156 Nervous system    04725 Cholinergic synapse     100769337 (Jak2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100769337 (Jak2)    05207 Chemical carcinogenesis - receptor activation     100769337 (Jak2)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     100769337 (Jak2)   09172 Infectious disease: viral    05161 Hepatitis B     100769337 (Jak2)    05164 Influenza A     100769337 (Jak2)    05168 Herpes simplex virus 1 infection     100769337 (Jak2)    05167 Kaposi sarcoma-associated herpesvirus infection     100769337 (Jak2)   09171 Infectious disease: bacterial    05152 Tuberculosis     100769337 (Jak2)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     100769337 (Jak2)    05140 Leishmaniasis     100769337 (Jak2)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     100769337 (Jak2)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     100769337 (Jak2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100769337 (Jak2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:cge01001]     100769337 (Jak2) Enzymes [BR:cge01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      100769337 (Jak2) Protein kinases [BR:cge01001]  Non-receptor tyrosine kinases   JAK family [OT]    100769337 (Jak2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 FERM_F1 SH2_1 Jak1_Phl ABC1 FERM_C_FAK1 RIO1 Kinase-like FERM_M Motif Other DBs NCBI-GeneID:  100769337 NCBI-ProteinID:  XP_027262242 LinkDB All DBs Position 3:complement(32155602..32220529) Genome browser AA seq 1132 aa AA seqDB search MGMACLTMTEMEATSTSPVHPNGDIPGNANSVKQIDPVLQVYLYHSLGKAEGDYLKFPIG EYVAEEICVAASKACGITPVYHNMFALMSETERIWYPPNHVFHIDESTRHNVLYRIRFYF PHWYCSGSNRTYRYGVSRGAEAPLLDDFVMSYLFAQWRHDFVHGWIKVPVTHETQEECLG MAVLDMMRIAKEKDQTPLAVYNSVSYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQQF SQCKATARNLKLKYLINLETLQSAFYTEQFEVKESARGPSGEEIFATIIITGNGGIQWSR GRHKESETLTEQGLQLYCDFPDIIDVSIKQANQECSNESRLVTIHKQDGKILEIELSSLR EALSFVSLVDGYYRLTADAHHYLCKEVAPPSVLENMHSNCHGPISMDFAISKLKKAGNQM GLYVLRCSPKDFNKYFLTFAVERENVVEYKHCLIMKNENREYNLSGTKRNFSNLKDLLNC YQMETVRSDSIIFQFTKCCPPKPKDKSNLLVFRTNGISDVQMSPTLQRHNNVNQMVFHKI RNEDLIFNESLGQGTFTKIFKGLRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM MSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLGVAKQLAWA MHFLEEKSLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVP PECIENPKNLNLATDKWSFGTTLWEICSGGDKPLNALDSQRKLQFYEDKHQLPAPKWTEL ANLINNCMDYEPDFRPAFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRD PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE ILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQI CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFW YAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPVEFMRMIGNDKQGQMIVFHLIE LLKNNGRLPRPEGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDSLAA NT seq 3399 nt NT seq  +upstreamnt  +downstreamnt atgggaatggcttgccttacaatgacagaaatggaggccacctccacatctcctgtacat ccgaatggcgatattcctggaaatgctaattctgtgaagcagatagatccagtccttcaa gtgtatctgtaccattctcttgggaaagccgaaggagactatctgaagtttccaattgga gagtatgttgcagaagaaatttgtgtggctgcttctaaagcttgtggtattacgcctgtg tatcataatatgtttgctttaatgagtgaaacagaaaggatctggtacccacccaaccat gtcttccacatagatgagtcaaccaggcataatgtactctacagaataagattttacttt ccgcactggtattgcagtggcagcaacagaacctatcgatatggagtatctcgtggggct gaagctcctcttcttgatgactttgtcatgtcttacctttttgctcagtggcggcatgat tttgtgcacggatggataaaagtgcccgtgactcatgaaactcaagaagagtgtcttgga atggcagtactagatatgatgagaatagctaaagagaaggaccaaactccactagctgtc tataactctgtcagctacaagacattcttaccaaagtgcgttcgagcaaagatccaagac tatcatattttaacccggaagcgaataaggtatagatttcgcagattcattcagcagttc agtcaatgcaaagccactgccagaaacttgaaacttaagtatcttataaacttggaaacc ctgcagtctgccttctacacagagcaatttgaagtaaaagaatctgcaagaggtccttca ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga gggagacataaggaaagtgagacactgacagaacagggtttacagttatattgtgatttt cctgatattattgatgtcagcattaagcaagcaaaccaggaatgctcaaatgaaagtaga cttgtaactatccataagcaagatggtaaaattttggaaatagaacttagctccttaaga gaagctttgtcatttgtgtccttagtggatggctattacagactcactgcagacgcacat cattacctctgtaaggaagtagcccctccctctgtgctggagaacatgcacagcaactgc cacggccccatctcaatggattttgccattagtaaactaaagaaagcaggtaaccagatg ggactgtatgtactccgatgtagccctaaggactttaacaaatactttctgacctttgct gtggagcgagaaaatgttgttgaatataaacactgtctgattatgaagaatgagaataga gagtacaacctcagtgggacaaagaggaacttcagtaatcttaaggaccttttgaattgc taccagatggaaactgtgcgctcagacagcatcatcttccagtttactaaatgctgtccc ccaaagccaaaagataaatcaaatcttcttgtcttcagaacaaatggtatttctgatgtt caaatgtcaccaacattacagaggcataataatgtgaaccaaatggtgtttcacaaaatc agaaatgaagatttgatatttaatgaaagtcttggccaaggtacttttacaaaaattttt aaaggtttaagaagagaagttggagactatggccaactgcatgaaacagaagttcttttg aaagttctggataaagcacatagaaattattcggagtctttctttgaggcggcaagcatg atgagccagctttctcacaagcacttggttttgaattatggtgtgtgtgtctgtggagag gagaatattctggttcaagagtttgtaaaatttggatccctggatacatacctgaaaaaa aacaaaaattctataaatatactatggaaacttggagtggctaaacagttggcatgggcc atgcattttctagaagaaaaatcccttattcatgggaatgtgtgtgccaaaaatatcctg cttatcagagaagaagacaggaaaacagggaatccacctttcatcaaacttagtgatcct ggcattagcatcacagtgctaccgaaggacattcttcaggagagaataccatgggtacca cctgaatgcattgaaaatcctaaaaatctaaatctggcaacagacaaatggagttttggc accactctgtgggaaatctgcagtggaggagacaagcccctgaatgctctggactctcaa agaaagctgcagttttatgaagataagcatcagcttcctgcacctaagtggacagaatta gcaaaccttattaacaattgcatggattatgaaccagatttcaggcctgcctttagagcc attatccgtgatcttaacagcctgtttaccccagactatgaactactaacagaaaatgac atgctgccaaacatgagaataggtgccctaggattttctggtgcttttgaagacagagac cctacacagtttgaagagagacacttgaaatttctacagcaacttggcaagggtaatttt gggagtgtggagatgtgccgatatgaccctctacaggacaacactggggaggtggtggct gttaaaaagctccagcacagcactgaagagcatctcagagactttgaaagggaaattgaa atcctgaaatccttgcagcatgacaacattgtaaagtacaagggagtgtgctacagtgct ggtcgacgcaacctaagattaattatggaatatttgccatatggaagtttacgagactat ctccaaaaacataaagaacggatagatcacaaaaaacttctgcagtacacatctcagata tgcaagggcatggagtatcttggtacaaaaaggtatatccacagggatctggcaacaaga aacatactggtagaaaatgagaacagagttaaaataggagattttggattaaccaaagtc ttgccacaggacaaagaatactacaaagtaaaagaaccaggtgaaagtcccatattctgg tatgctccagaatccctgacagagagcaagttttctgttgcctcggatgtgtggagcttt ggcgtagttctgtatgagcttttcacatacattgagaagagtaaaagtccaccagtggaa tttatgcgaatgattggcaatgataaacaaggacagatgattgtgttccatttgatagag cttctgaagaataatggaagattaccgagaccagaggggtgcccggatgagatttacatg atcatgacagaatgctggaacaacaatgtcaatcagcgaccctctttcagggacctagca cttcgggtggatcaaatccgggacagtttggctgcgtga

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