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Carlito syrichta (Philippine tarsier): 103250706
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Entry
103250706 CDS
T07836
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2 isoform X1
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
csyr
Carlito syrichta (Philippine tarsier)
Pathway
csyr01521
EGFR tyrosine kinase inhibitor resistance
csyr04062
Chemokine signaling pathway
csyr04148
Efferocytosis
csyr04151
PI3K-Akt signaling pathway
csyr04217
Necroptosis
csyr04550
Signaling pathways regulating pluripotency of stem cells
csyr04630
JAK-STAT signaling pathway
csyr04658
Th1 and Th2 cell differentiation
csyr04659
Th17 cell differentiation
csyr04725
Cholinergic synapse
csyr04917
Prolactin signaling pathway
csyr04920
Adipocytokine signaling pathway
csyr04933
AGE-RAGE signaling pathway in diabetic complications
csyr04935
Growth hormone synthesis, secretion and action
csyr05140
Leishmaniasis
csyr05145
Toxoplasmosis
csyr05152
Tuberculosis
csyr05161
Hepatitis B
csyr05164
Influenza A
csyr05167
Kaposi sarcoma-associated herpesvirus infection
csyr05168
Herpes simplex virus 1 infection
csyr05200
Pathways in cancer
csyr05207
Chemical carcinogenesis - receptor activation
csyr05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
csyr05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
csyr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
103250706 (JAK2)
04151 PI3K-Akt signaling pathway
103250706 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
103250706 (JAK2)
09143 Cell growth and death
04217 Necroptosis
103250706 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
103250706 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
103250706 (JAK2)
04659 Th17 cell differentiation
103250706 (JAK2)
04062 Chemokine signaling pathway
103250706 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
103250706 (JAK2)
04917 Prolactin signaling pathway
103250706 (JAK2)
04935 Growth hormone synthesis, secretion and action
103250706 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
103250706 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103250706 (JAK2)
05207 Chemical carcinogenesis - receptor activation
103250706 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
103250706 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
103250706 (JAK2)
05164 Influenza A
103250706 (JAK2)
05168 Herpes simplex virus 1 infection
103250706 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
103250706 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
103250706 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
103250706 (JAK2)
05140 Leishmaniasis
103250706 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
103250706 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
103250706 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103250706 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
csyr01001
]
103250706 (JAK2)
Enzymes [BR:
csyr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
103250706 (JAK2)
Protein kinases [BR:
csyr01001
]
Non-receptor tyrosine kinases
JAK family [OT]
103250706 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
103250706
NCBI-ProteinID:
XP_008047488
Ensembl:
ENSTSYG00000010422
UniProt:
A0A1U7STL7
LinkDB
All DBs
Position
Unknown
AA seq
1131 aa
AA seq
DB search
MGMACLTMTEMEETSVSTYQNGDISGNTNSVKQIDPILQVYLYHSLGKAEGDYLKFPTGE
YVAEEICIAASKACGITPVYQNMFALMSETDRIWYPPNHVFHIDESTRHNVLYRIRFYFP
HWYCSGSSRTYRHGISRGAEAPLLDDFVMSYLFAQWRHDFVHGWIKVPVTHETQEECLGM
AVLDMMRIAKEKDQTPLAIYNSISYKTFLPKCIRARIQDYHILTRKRIRYRFRRFIQQFS
QCKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSRG
KHKESETLTEQDLQLYCDFPNIIDVSIKQANKEGSNESRVVTIHKQDGKNLEIELSSLRE
ALSFVSLIDGYYRLTADAHHYLCKEVAPPTVLANIQSNCHGPISMDFAISKLKKAGNQTG
LYVLRCSPKDFNKYFLTFAVERENIIEYKHCLITKNENGEYNLSGTKKNFSNLKDLLNCY
QMETVRSDSIIFQFTKCCPPRPKDKSNLLVFRTNGVSDVPTSPTLQRHNNVNQMVFHKIR
NEDLIFNESLGQGTFTKIFKGIRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMM
SQLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNFINILWKLEVAKQLAWAM
HFLEEKTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPP
ECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTELA
NLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDP
TQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEI
LKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYIQKHKERIDHKKLLQYTSQIC
KGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWY
APESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIEL
LKNNGRLPRPDGCPDEIYMIMTQCWNNNVNQRPSFRDLALRVDQIRDNMAE
NT seq
3396 nt
NT seq
+upstream
nt +downstream
nt
atgggaatggcttgccttacaatgacagaaatggaagaaacatccgtatctacatatcag
aatggtgatatttctggaaataccaattcagtgaagcagatagatcccatccttcaggtg
tatctttaccattccctggggaaagcagagggagattacctgaagtttccaactggggaa
tatgttgcggaagaaatttgtattgctgcttctaaagcttgtggtatcacacctgtatat
cagaacatgtttgctttaatgagtgagacagataggatctggtatccacccaaccatgtc
ttccatatagatgagtcaaccaggcataatgtactctacagaataagattttactttcct
cattggtattgcagcggcagcagcagaacctatcggcatggaatatctcgaggtgctgaa
gctcctcttcttgatgacttcgtcatgtcttacctttttgctcagtggcggcatgatttt
gtgcatggatggataaaagtacctgtgactcatgaaacacaggaagaatgtcttggaatg
gcggtgttagatatgatgagaatagccaaagaaaaggatcaaactccactggccatctat
aactctatcagttacaagacattcttaccaaaatgtattcgagcaaggatccaagactat
catattttgacaaggaagcgaataaggtacagatttcgaagatttattcagcagttcagc
caatgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaactctt
cagtctgccttctacacagagcaatttgaagtaaaagaacctggaagaggtccttcaggt
gaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaagaggg
aaacataaagaaagtgagacactgacagaacaggatttacagttatattgtgattttcct
aatattattgatgtcagtattaagcaagcaaacaaagaaggctcgaatgaaagcagagtt
gtaactatccataagcaagatggtaaaaatctggaaattgaacttagctcattaagagaa
gctttgtcttttgtgtcgttaattgatggatattatagattaactgcagatgcacatcat
tacctctgtaaagaagtagcacctccaacagtgcttgcaaatatacaaagcaactgtcat
ggcccaatttcaatggattttgccatcagtaaactgaagaaggcaggtaatcagactgga
ctgtatgtacttcgttgcagtcctaaggactttaataagtattttttgacttttgctgtt
gagcgagaaaatatcattgaatataaacattgtttgatcacaaaaaatgagaatggagag
tacaaccttagtgggactaagaagaacttcagtaatcttaaagatcttttgaattgttac
cagatggaaactgttcgctcagacagtataattttccagtttactaaatgctgtccccca
agaccaaaagataaatcaaaccttttagtatttagaaccaatggtgtttctgatgtacca
acctcaccaacgttgcagaggcataataatgtgaaccaaatggtgtttcataaaatcaga
aatgaagatttgatatttaatgaaagccttggccaaggcacttttacaaaaatttttaaa
ggcataagaagagaagtgggagactatggtcaactgcatgaaacagaagttcttttaaaa
gttctggataaagcacatagaaactattcagagtctttctttgaagcagcaagcatgatg
agtcagctttctcacaagcatttggttttaaattatggagtatgtgtctgtggagatgag
aatattctggttcaggagtttgtaaaatttggatcactagatacatacctgaaaaaaaat
aaaaattttataaatatattatggaaacttgaagtggctaaacagctggcatgggccatg
cattttctagaagaaaaaacccttattcatgggaatgtatgtgccaaaaatattctactc
atcagagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgatcctggc
attagtattacagttttaccaaaagacattcttcaggagagaataccatgggtaccacct
gaatgcattgaaaatcctaaaaatctaaatttggcaacagacaaatggagttttggcacc
actttgtgggaaatctgcagtggaggagataagcctctgagtgctctggattctcaaagg
aagctacagttttatgaagacaggcaccagcttcctgcaccaaagtggacagaattagca
aaccttattaataattgtatggattacgaaccagactttaggccttctttcagagccatc
atacgagatcttaatagtttgtttactccagattatgaactattaacggaaaatgacatg
ttaccaaatatgaggataggtgccctagggttttcgggtgcttttgaagacagggaccct
acacagtttgaagagaggcacttgaaatttctacagcaacttggcaagggtaattttggg
agtgtggagatgtgccggtatgaccctctacaggacaacactggggaagtggtggctgta
aaaaagcttcagcacagtactgaagagcaccttagagactttgaaagggaaatcgaaatc
ctgaaatccctacaacacgacaacattgtaaagtacaagggagtgtgctacagtgctggt
cggcgtaatctaagattaattatggaatatttgccatatggaagtttacgagactatatc
caaaaacataaagaacggatagatcacaaaaaacttcttcagtatacatctcagatatgc
aagggtatggagtatcttggtacaaaaaggtatatccacagggatttggcaacaaggaat
atattggtggagaatgagaacagagttaaaattggagattttgggttaaccaaagtcttg
ccacaagataaagaatattacaaagttaaagaacctggtgaaagtcccatattctggtat
gctccagaatcactgacagagagcaagttttctgtggcctcagatgtttggagctttgga
gtggttctgtatgaactttttacatatattgagaagagtaaaagtccaccagcggaattt
atgcgtatgattggcaatgacaagcaaggacagatgattgtgttccatttgatagaactt
ttgaagaataatggaagattaccaagaccagatggatgcccagatgagatttatatgatc
atgacacaatgctggaacaataatgtaaatcagcgtccctcttttagggacctggctctt
cgagtggatcaaataagggacaacatggctgaatga
DBGET
integrated database retrieval system