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Equus caballus (horse): 100051487
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Entry
100051487 CDS
T01058
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2 isoform X1
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb01521
EGFR tyrosine kinase inhibitor resistance
ecb04062
Chemokine signaling pathway
ecb04148
Efferocytosis
ecb04151
PI3K-Akt signaling pathway
ecb04217
Necroptosis
ecb04550
Signaling pathways regulating pluripotency of stem cells
ecb04630
JAK-STAT signaling pathway
ecb04658
Th1 and Th2 cell differentiation
ecb04659
Th17 cell differentiation
ecb04725
Cholinergic synapse
ecb04917
Prolactin signaling pathway
ecb04920
Adipocytokine signaling pathway
ecb04933
AGE-RAGE signaling pathway in diabetic complications
ecb04935
Growth hormone synthesis, secretion and action
ecb05140
Leishmaniasis
ecb05145
Toxoplasmosis
ecb05152
Tuberculosis
ecb05161
Hepatitis B
ecb05164
Influenza A
ecb05167
Kaposi sarcoma-associated herpesvirus infection
ecb05168
Herpes simplex virus 1 infection
ecb05200
Pathways in cancer
ecb05207
Chemical carcinogenesis - receptor activation
ecb05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
ecb05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
100051487 (JAK2)
04151 PI3K-Akt signaling pathway
100051487 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
100051487 (JAK2)
09143 Cell growth and death
04217 Necroptosis
100051487 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
100051487 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
100051487 (JAK2)
04659 Th17 cell differentiation
100051487 (JAK2)
04062 Chemokine signaling pathway
100051487 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
100051487 (JAK2)
04917 Prolactin signaling pathway
100051487 (JAK2)
04935 Growth hormone synthesis, secretion and action
100051487 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
100051487 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100051487 (JAK2)
05207 Chemical carcinogenesis - receptor activation
100051487 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100051487 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
100051487 (JAK2)
05164 Influenza A
100051487 (JAK2)
05168 Herpes simplex virus 1 infection
100051487 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
100051487 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
100051487 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
100051487 (JAK2)
05140 Leishmaniasis
100051487 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100051487 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
100051487 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100051487 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ecb01001
]
100051487 (JAK2)
Enzymes [BR:
ecb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100051487 (JAK2)
Protein kinases [BR:
ecb01001
]
Non-receptor tyrosine kinases
JAK family [OT]
100051487 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
Kdo
ABC1
RIO1
FERM_C_FAK1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
100051487
NCBI-ProteinID:
XP_001492713
Ensembl:
ENSECAG00000009119
VGNC:
19213
UniProt:
A0A9L0T0U7
LinkDB
All DBs
Position
23:25863482..25999367
Genome browser
AA seq
1131 aa
AA seq
DB search
MGMACLTMAEMEGTSVSVHQNGDIPGNANSVKQVDPVLQVYLYHSLEKAEGDYLKFPTGE
YVAEEICVAASKACGITPVYHSMFALMSETERIWYPPNHVFHIDESARHSVLYRIRFYFP
YWYCNGSNRTYRHGISRGAEAPLLDDFVMSYLFAQWRHDFLHGWVKVPVTHETQEECLGM
AVLDMMRIAKEKDQTPLTIYSSISYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIEQFS
HCKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSRG
KHKESETLTEQNLQLYCDFPDIIDVNIKQAHQEGSNESRIVTIHKQDGKTLEIELSSLRE
ALSFVSLIDGYYRLTADAHHYLCKEVAPPMVLENIQSNCHGPISMDFAISKLKKAGNQTG
LYVLRCSPKDFNKYFLTFAVERENVIEHKHCLITKNENGEYNLSGTKKNFSSLKDLLNCY
QMETVRSDSIIFQFTKCCPPKPKDKSNLLVFRTNGVSEVPTSPTLQRHNNVNQMVFHKIR
NEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKSHRNYSESFFEAASMM
SQLSHKYLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLEVAKQLAWAM
HFLEEKTLIHGNVCAKNILLTREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPP
ECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTELA
NLINSCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDP
TQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEI
LKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQIC
KGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWY
APESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIEL
LKNNGRLPKPDGCPDEIYVIMTQCWNNNVNQRPSFRDLALRVDQIRDNMAG
NT seq
3396 nt
NT seq
+upstream
nt +downstream
nt
atgggaatggcttgccttacaatggcagaaatggaaggaacatctgtgtctgtgcatcag
aatggtgatattcctggaaatgctaattctgtaaagcaagtagatccagtcctacaggtg
tatctttatcattcccttgagaaagctgaaggagattacctgaagtttccaactggggag
tatgttgcggaagaaatttgtgttgctgcttctaaagcttgcggaatcacacctgtgtat
cacagtatgttcgctttaatgagtgaaacagaaagaatctggtatccccccaaccatgtc
ttccatatagatgaatcagccaggcacagtgtactctacagaataagattttactttcct
tactggtattgtaatggcagcaacagaacctatcggcatggaatatctcgaggtgctgaa
gctcctcttcttgatgactttgtcatgtcttacctttttgctcagtggcggcatgacttt
ttgcatggatgggtaaaagtacctgtgactcatgaaacacaggaagaatgtcttgggatg
gcagtgttagatatgatgagaatagccaaagaaaaggatcaaaccccactgaccatctat
agctctatcagctacaagacattcttaccaaaatgtgttcgagcaaagatccaagactat
catattttgacaaggaaacgaataaggtacagatttcgcagatttattgagcaattcagc
cattgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaactctt
cagtctgccttctacacagagcaatttgaagtaaaagaacctggaagaggtccttcaggt
gaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaagaggg
aaacataaagaaagtgagacactgacagaacagaatttacagttatattgtgattttcct
gatattattgatgtgaatattaagcaagcacaccaagaaggctcaaatgaaagcagaatt
gtaactatccataagcaagatggtaaaactctggaaattgaacttagctcattgagagaa
gctttgtcttttgtgtcattaattgatggatattatagattaactgcagatgcacatcat
tacctctgtaaagaagtagcacctccaatggtgcttgaaaatatacaaagcaactgtcat
ggcccaatttcaatggattttgccatcagcaagctgaagaaagcaggtaatcaaactgga
ctctatgtacttcgatgcagtcctaaggactttaataaatattttctgacttttgctgtc
gagcgagaaaatgtcattgaacataagcactgtttgattacaaaaaatgagaatggagaa
tacaacctaagtgggactaagaagaacttcagtagtcttaaagatcttttgaattgctat
cagatggaaactgttcgctcagacagtataattttccagtttactaaatgctgtccccca
aagccaaaagataaatcaaaccttctagtcttcagaaccaatggtgtttctgaggtaccg
acctcaccaacattacagaggcataataatgtgaaccaaatggtgtttcacaaaatcaga
aatgaagatttgatatttaatgaaagccttggccaaggcacttttacaaaaatttttaaa
ggtgtaagaagagaagtaggagactatggtcaactgcatgaaacagaagttcttttgaaa
gttctggataaatcacatagaaactactcagagtctttctttgaagcagcaagcatgatg
agccagctttctcacaaatatctggttttaaattatggagtgtgtgtctgtggagaggag
aatattctggttcaggagtttgtaaaatttggatcactagatacatatctgaaaaagaat
aaaaattctataaatatattatggaaacttgaagtagctaaacagttggcatgggccatg
cattttctagaagaaaaaacccttattcatgggaatgtgtgtgccaaaaatattctactt
accagagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgatcctggc
attagtattacagttttgccaaaggacattcttcaggagagaataccatgggtaccacct
gaatgcattgaaaatcctaaaaatctaaacttggcaacagacaaatggagttttggtacc
actttgtgggaaatttgcagtggaggagataagcctctgagtgctttggattctcaaaga
aagctacagttttatgaagataggcaccagcttcctgcaccaaagtggacagaattagca
aatcttatcaatagttgtatggattacgaaccagattttagaccttctttcagagccatc
atacgtgatcttaatagtttgtttactccagattatgagctgttaacagaaaatgacatg
ttaccaaatatgaggataggtgccctagggttttctggtgctttcgaagaccgagaccct
acgcagtttgaagagagacacttgaaatttctacagcaacttggcaagggtaattttggg
agtgtggagatgtgccgttatgaccctctacaagacaacactggggaggtggtggctgtg
aaaaagctccagcacagtactgaagagcacctcagagactttgaaagggaaattgaaatc
cttaaatccctgcagcatgacaacattgtaaagtacaagggagtgtgctacagtgctggc
cggcgtaatctaagattaattatggaatatttaccatatggaagtttacgagactatctc
caaaaacataaagaacggatagatcataaaaaacttctgcagtacacatctcagatatgc
aagggtatggaatatcttggtacaaaaagatatatccacagggatctggcaacaaggaat
atattggtggaaaatgaaaacagagttaaaattggagattttgggttaaccaaagtcttg
ccacaagacaaagaatactacaaagtgaaagaacctggtgaaagtcccatattctggtat
gctccagaatcactgacagagagcaagttttctgtggcctcagatgtttggagctttgga
gtggttctgtatgaactttttacatatattgagaagagtaaaagtccaccagcggaattt
atgcgtatgattggcaatgacaaacaaggacagatgattgtgtttcatttgatagaactc
ctgaagaataatggaagattaccaaaaccagatggatgcccagatgagatttatgtgatc
atgacacaatgctggaacaacaatgtaaatcagcgcccctctttcagagacctagctctt
cgagttgatcaaataagggacaacatggctggatga
DBGET
integrated database retrieval system
