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Enhydra lutris kenyoni (northern sea otter): 111151941
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Entry
111151941 CDS
T05871
Name
(RefSeq) serine/threonine-protein kinase B-raf isoform X1
KO
K04365
B-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
elk
Enhydra lutris kenyoni (northern sea otter)
Pathway
elk01521
EGFR tyrosine kinase inhibitor resistance
elk01522
Endocrine resistance
elk04010
MAPK signaling pathway
elk04012
ErbB signaling pathway
elk04015
Rap1 signaling pathway
elk04024
cAMP signaling pathway
elk04062
Chemokine signaling pathway
elk04068
FoxO signaling pathway
elk04150
mTOR signaling pathway
elk04270
Vascular smooth muscle contraction
elk04510
Focal adhesion
elk04650
Natural killer cell mediated cytotoxicity
elk04720
Long-term potentiation
elk04722
Neurotrophin signaling pathway
elk04726
Serotonergic synapse
elk04730
Long-term depression
elk04810
Regulation of actin cytoskeleton
elk04910
Insulin signaling pathway
elk04914
Progesterone-mediated oocyte maturation
elk04928
Parathyroid hormone synthesis, secretion and action
elk04934
Cushing syndrome
elk05010
Alzheimer disease
elk05022
Pathways of neurodegeneration - multiple diseases
elk05034
Alcoholism
elk05160
Hepatitis C
elk05161
Hepatitis B
elk05200
Pathways in cancer
elk05205
Proteoglycans in cancer
elk05208
Chemical carcinogenesis - reactive oxygen species
elk05210
Colorectal cancer
elk05211
Renal cell carcinoma
elk05212
Pancreatic cancer
elk05213
Endometrial cancer
elk05214
Glioma
elk05215
Prostate cancer
elk05216
Thyroid cancer
elk05218
Melanoma
elk05219
Bladder cancer
elk05220
Chronic myeloid leukemia
elk05221
Acute myeloid leukemia
elk05223
Non-small cell lung cancer
elk05224
Breast cancer
elk05225
Hepatocellular carcinoma
elk05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
elk00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
111151941
04012 ErbB signaling pathway
111151941
04015 Rap1 signaling pathway
111151941
04068 FoxO signaling pathway
111151941
04024 cAMP signaling pathway
111151941
04150 mTOR signaling pathway
111151941
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
111151941
09142 Cell motility
04810 Regulation of actin cytoskeleton
111151941
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
111151941
04062 Chemokine signaling pathway
111151941
09152 Endocrine system
04910 Insulin signaling pathway
111151941
04914 Progesterone-mediated oocyte maturation
111151941
04928 Parathyroid hormone synthesis, secretion and action
111151941
09153 Circulatory system
04270 Vascular smooth muscle contraction
111151941
09156 Nervous system
04726 Serotonergic synapse
111151941
04720 Long-term potentiation
111151941
04730 Long-term depression
111151941
04722 Neurotrophin signaling pathway
111151941
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
111151941
05205 Proteoglycans in cancer
111151941
05208 Chemical carcinogenesis - reactive oxygen species
111151941
09162 Cancer: specific types
05210 Colorectal cancer
111151941
05212 Pancreatic cancer
111151941
05225 Hepatocellular carcinoma
111151941
05226 Gastric cancer
111151941
05214 Glioma
111151941
05216 Thyroid cancer
111151941
05221 Acute myeloid leukemia
111151941
05220 Chronic myeloid leukemia
111151941
05218 Melanoma
111151941
05211 Renal cell carcinoma
111151941
05219 Bladder cancer
111151941
05215 Prostate cancer
111151941
05213 Endometrial cancer
111151941
05224 Breast cancer
111151941
05223 Non-small cell lung cancer
111151941
09172 Infectious disease: viral
05161 Hepatitis B
111151941
05160 Hepatitis C
111151941
09164 Neurodegenerative disease
05010 Alzheimer disease
111151941
05022 Pathways of neurodegeneration - multiple diseases
111151941
09165 Substance dependence
05034 Alcoholism
111151941
09167 Endocrine and metabolic disease
04934 Cushing syndrome
111151941
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
111151941
01522 Endocrine resistance
111151941
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
elk01001
]
111151941
Enzymes [BR:
elk01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
111151941
Protein kinases [BR:
elk01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
111151941
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
ABC1
C1_2
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
111151941
NCBI-ProteinID:
XP_022365887
UniProt:
A0A2Y9JXN1
LinkDB
All DBs
Position
Unknown
AA seq
817 aa
AA seq
DB search
MAALSGGGGGSGAEQGQALFNGDMEPEAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHI
EALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLGNGTDFSVSSSASTDTVT
SSSSSSLSVLPSSLSVFQNPTDVSRSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSL
KKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKT
FFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPIP
QEEASIAETALSSGSSPSAPPSDSTGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQRD
RSSSAPNVHINTIEPVNIDDLIRDQGFRSDGGSTTGLSATPPASLPGSLTNVKALQKSPG
PQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVA
VKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHL
HIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVK
SRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINN
RDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSL
PKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYDTEFSMHKLVWNRMEFPIHQK
REECFRNQNSLLPVFLLQHKYHVHTSLPTPRKEEERA
NT seq
2454 nt
NT seq
+upstream
nt +downstream
nt
atggcggcgctgagcggcggcggcggcggcagcggcgcggagcagggccaggctctgttc
aacggggatatggagcccgaggccggcgccggcgccgcggcctcttcggctgcggaccct
gccattcccgaggaggtgtggaatatcaaacaaatgattaagttgacacaggaacatata
gaagccctattggacaaatttggtggggagcataatccaccatcaatatatctggaggcc
tatgaagaatacaccagcaagctagatgccctccaacagcgagaacaacagttattggaa
tccctggggaatggaactgatttttctgtttctagctctgcatcaacagacaccgttaca
tcttcttcctcctctagcctttcagtgctaccttcatctctttcagtttttcaaaatccc
acagatgtatcacggagcaatccaaagtcaccacaaaaacctatcgttagagtcttcctg
cccaataaacagaggacagtggtacctgcaagatgtggagttacagtccgagacagtcta
aagaaagctctgatgatgagaggtctaatcccagagtgctgtgctgtttacagaattcag
gatggagagaagaaaccgattggctgggacactgatatttcctggctcactggagaggaa
ctacatgtagaagtgttggaaaatgtcccgcttaccacacacaactttgtacggaaaact
tttttcaccttagcattttgtgacttttgtcgaaagctgcttttccagggttttcgctgt
caaacatgtggttataaatttcaccagcgttgtagtacagaggtcccactgatgtgtgtt
aattatgaccaacttgatttgctgtttgtctccaagttctttgaacaccacccaatacca
caggaggaggcctccatagcagagactgccctttcgtccggatcatccccttctgctccc
ccctccgattctactgggccccaaatcctcaccagtccgtctccttcaaaatccattcca
attccacagcctttccgaccagcagatgaagatcatcgaaatcaatttggacaacgagac
cggtcctcatcagctccaaatgtgcatataaacacaatagaacctgtcaatattgatgac
ttgattagagaccaagggtttcgtagtgacggaggatcaaccactggtttgtctgccacc
ccccctgcctcattgcctggctcactcactaatgtgaaagcattacagaaatctccagga
cctcagcgggaaaggaaatcatcttcatcctcagaagataggaatcgaatgaaaacactt
ggtagacgggattcaagtgatgattgggagattcctgatgggcagatcacagtgggacag
agaatcggatccgggtcatttgggacagtctacaagggaaagtggcatggtgatgtggca
gtgaaaatgttgaatgtgacagcgcccacacctcagcagttacaggccttcaaaaatgaa
gtaggagtactcaggaaaactcgacatgtgaacatcctacttttcatgggctattcaaca
aagccccaactagctattgttacccagtggtgtgagggctccagcttatatcaccatctc
cacatcatcgagaccaaatttgagatgatcaagcttatagatattgcacggcagactgcg
cagggcatggattacttacacgccaagtcaatcatccacagagacctcaagagtaataat
atttttcttcatgaagacctcacagtaaaaataggtgattttggtctagccacagtgaaa
tctcgatggagtgggtcccatcagtttgaacagttgtctggatccattttgtggatggcg
ccagaagtgatccgaatgcaagataaaaacccatatagctttcagtcagatgtctatgca
tttgggattgttctatatgaattgatgaccggacagttaccttattcaaacatcaacaac
agggaccagataatttttatggttggacgaggatatctttctccagatctcagtaaggta
cggagtaactgtccaaaagccatgaagagattgatggcagagtgcctaaaaaagaaaaga
gatgagaggccactctttccccaaattctcgcctctattgagctgctggcccgctcattg
ccaaaaattcaccgcagtgcatcagaaccctccttgaatcgggctggcttccaaacagag
gattttagtctatatgcttgtgcttctccaaaaacacccatccaggcagggggatatgat
acagaattttcaatgcataagctggtgtggaacagaatggaatttcccatccaccaaaag
agggaagaatgttttaggaaccagaattctctgctgccagtgtttcttcttcaacacaaa
taccacgtgcatacaagtctgcccactcccaggaaggaagaggagagagcctga
DBGET
integrated database retrieval system