Svoboda
|
Graniru
|
BBC Russia
|
Golosameriki
|
Facebook
Enhydra lutris kenyoni (northern sea otter): 111153517
Help
Entry
111153517 CDS
T05871
Name
(RefSeq) tyrosine-protein kinase JAK2
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
elk
Enhydra lutris kenyoni (northern sea otter)
Pathway
elk01521
EGFR tyrosine kinase inhibitor resistance
elk04062
Chemokine signaling pathway
elk04148
Efferocytosis
elk04151
PI3K-Akt signaling pathway
elk04217
Necroptosis
elk04550
Signaling pathways regulating pluripotency of stem cells
elk04630
JAK-STAT signaling pathway
elk04658
Th1 and Th2 cell differentiation
elk04659
Th17 cell differentiation
elk04725
Cholinergic synapse
elk04917
Prolactin signaling pathway
elk04920
Adipocytokine signaling pathway
elk04933
AGE-RAGE signaling pathway in diabetic complications
elk04935
Growth hormone synthesis, secretion and action
elk05140
Leishmaniasis
elk05145
Toxoplasmosis
elk05152
Tuberculosis
elk05161
Hepatitis B
elk05164
Influenza A
elk05167
Kaposi sarcoma-associated herpesvirus infection
elk05168
Herpes simplex virus 1 infection
elk05200
Pathways in cancer
elk05207
Chemical carcinogenesis - receptor activation
elk05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
elk05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
elk00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
111153517
04151 PI3K-Akt signaling pathway
111153517
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
111153517
09143 Cell growth and death
04217 Necroptosis
111153517
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
111153517
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
111153517
04659 Th17 cell differentiation
111153517
04062 Chemokine signaling pathway
111153517
09152 Endocrine system
04920 Adipocytokine signaling pathway
111153517
04917 Prolactin signaling pathway
111153517
04935 Growth hormone synthesis, secretion and action
111153517
09156 Nervous system
04725 Cholinergic synapse
111153517
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
111153517
05207 Chemical carcinogenesis - receptor activation
111153517
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
111153517
09172 Infectious disease: viral
05161 Hepatitis B
111153517
05164 Influenza A
111153517
05168 Herpes simplex virus 1 infection
111153517
05167 Kaposi sarcoma-associated herpesvirus infection
111153517
09171 Infectious disease: bacterial
05152 Tuberculosis
111153517
09174 Infectious disease: parasitic
05145 Toxoplasmosis
111153517
05140 Leishmaniasis
111153517
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
111153517
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
111153517
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
111153517
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
elk01001
]
111153517
Enzymes [BR:
elk01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
111153517
Protein kinases [BR:
elk01001
]
Non-receptor tyrosine kinases
JAK family [OT]
111153517
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
FERM_F2
FERM_F1
SH2_1
Pkinase
Jak1_Phl
SH2
FERM_C_FAK1
FERM_M
Motif
Other DBs
NCBI-GeneID:
111153517
NCBI-ProteinID:
XP_022368281
UniProt:
A0A2Y9K4R8
LinkDB
All DBs
Position
Unknown
AA seq
974 aa
AA seq
DB search
MGMACLTMTEMEGTSVSPVHQNGDIPGNANPVKQIDPLLQVYLYHSLEKAEGEYLKFPTG
EYVAEEICVAASKACGITPVYHSMFALMSETERIWYPPNHVFHIDESTRHNVLYRIRFYF
PYWYCNGSNRTYRYGISRGAEAPLLDDFVMAYLFAQWRHDFLHGWIKIPVTHETQEECLG
MAVLDMMRLAKEKDQTPLDIYSSISYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIEQF
SHCKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSR
GKHKESETLTEQDLQLYCDFPDIIDVTIKQASQEGSNESRIVAIHKQDGKNLEIELSSLK
EALSFVSLIDGYYRLTADAHHYLCKEVAPPMVLENIQSNCHGPILMDFAISKLKKAGNQT
GLYVLRCSPKDFNKYFLTFAVERENAIEYKHCLITKNENGEYNLSGTKKNFSNLKDLLNC
YQMETVRSDSIIFQFTKCCPPKLKDKSNLLVFRTSGVSDVPTSPTLQRHNNVNQMVFHKI
RNEDLMFNESLGQGTFTKIFKGIRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM
MSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLEVAKQLAWA
MHFLEEKALVHGNVCAKNILLIREEDRKTGNLPFIKLSDPGISITVLPKDILQERIPWVP
PECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTEL
ANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRD
PTQFEERHLKFLQQLGKFVCYRYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPP
AEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYLIMTECWNNNVNQRPSFRD
LALRVDQIRDNMAG
NT seq
2925 nt
NT seq
+upstream
nt +downstream
nt
atggggatggcttgccttacaatgacagaaatggaaggaacgtccgtatctcctgtacat
cagaatggtgatattcctggaaatgctaatccggtgaagcaaatagatccactcctgcag
gtgtatctttatcattctcttgagaaagctgaaggagagtatctgaagtttccaactggg
gagtatgttgcagaagaaatttgtgttgctgcttctaaagcttgtggaatcacaccagtg
tatcatagtatgtttgctttaatgagtgaaacagaaaggatttggtatccgcccaaccat
gtcttccatatagatgaatcaaccaggcacaatgtactctacagaataagattttacttt
ccttactggtattgtaacggcagcaacagaacctatcggtatgggatatctcgaggtgct
gaagctcctcttcttgacgactttgtcatggcctacctttttgctcagtggcggcatgat
tttttacatggatggataaaaatacccgtgactcatgaaacacaagaagagtgtcttgga
atggctgtattagatatgatgagactagccaaagagaaggatcagaccccattggacatc
tatagctctatcagctacaagacattcttaccaaaatgtgttcgagcaaagatccaagac
tatcatattttgacaaggaaacgaataaggtacagatttcgcagatttattgagcagttc
agccattgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaact
cttcagtctgccttctacacagagcaatttgaagtaaaagaacctggaagaggtccttca
ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga
gggaaacataaagaaagtgagacactgacagaacaggatttacagttatattgtgacttc
cctgatattattgatgttactattaagcaagcaagccaagaaggctcaaatgaaagtaga
attgtagctatacataagcaagatggtaaaaatctggaaattgaacttagctcattaaaa
gaagctttgtcctttgtgtcattaattgatggctattatagattaactgcagatgcacat
cattacctctgtaaagaagtagcacctccaatggtccttgaaaatatacaaagcaactgt
catggcccaattttaatggattttgccatcagtaaactgaagaaagcaggtaatcagact
ggactctacgtacttcgatgcagtcctaaggactttaataagtattttctgacttttgct
gttgagcgagaaaatgccatcgaatataagcactgtttgattacaaagaatgagaatgga
gaatacaacctcagtgggaccaagaagaacttcagtaaccttaaagatcttttgaattgc
taccagatggaaactgttcgctcagacagtataattttccagtttactaaatgttgtccc
ccaaagttgaaagataaatcaaaccttctagtcttcagaaccagtggcgtttctgatgtt
cccacatcaccaacattacagaggcataataatgtgaaccaaatggtgtttcacaaaatc
agaaatgaagatttgatgtttaatgaaagccttggccaaggcacttttacaaaaattttt
aaaggtataaggagagaagtaggagattatggtcaactacatgaaacagaagttctttta
aaagttctggataaagctcacagaaactattccgagtctttctttgaagcagcaagcatg
atgagccagctttctcacaagcatctagttttaaattatggagtgtgtgtctgtggggag
gagaatattctggttcaagagtttgtaaaatttggatccttagatacatatctgaaaaag
aataaaaattctataaatatattatggaaacttgaagtggctaaacagttggcatgggcc
atgcattttctagaagaaaaagcacttgttcatggaaatgtgtgtgccaaaaatattctg
cttatcagagaagaagacaggaagacaggaaatcttcctttcatcaaacttagtgatcct
ggtattagtattacagttttgccaaaggacattcttcaggagagaataccatgggtacca
cctgaatgcattgaaaatcctaaaaatctaaatttggcaacagacaaatggagttttggt
accactttgtgggaaatctgcagtggaggagataaacctctgagtgctttggattctcaa
agaaagctacagttttacgaagataggcaccagcttcctgcaccaaagtggacagaatta
gcaaatcttattaataattgtatggattatgaaccagatttcagaccttctttcagagcc
atcatacgagatcttaatagtttgtttactccagattatgaactattaacagaaaatgat
atgttaccaaatatgagaataggtgccctagggttttctggtgcttttgaagaccgagac
cctacacaatttgaagagagacacttgaaatttctacagcaacttggcaagttcgtatgt
tataggtatgctccagaatcattgacagagagcaagttttctgtggcttcagatgtttgg
agctttggagtggttctctatgaacttttcacatatattgagaagagtaaaagtccccca
gcggaatttatgcgtatgattggcaatgacaaacaaggacagatgattgtgtttcatttg
atagaactcctaaagaataacggaagattaccaagaccagatggatgcccagatgagatt
tatttgatcatgacggaatgctggaataataatgtcaatcaacgcccctcttttagagac
ctagctcttcgagttgatcaaataagggacaacatggctggatga
DBGET
integrated database retrieval system