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Equus przewalskii (Przewalski's horse): 103562070
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Entry
103562070 CDS
T04644
Symbol
MET
Name
(RefSeq) MET proto-oncogene, receptor tyrosine kinase
KO
K05099
proto-oncogene tyrosine-protein kinase Met [EC:
2.7.10.1
]
Organism
epz
Equus przewalskii (Przewalski's horse)
Pathway
epz01521
EGFR tyrosine kinase inhibitor resistance
epz04010
MAPK signaling pathway
epz04014
Ras signaling pathway
epz04015
Rap1 signaling pathway
epz04020
Calcium signaling pathway
epz04151
PI3K-Akt signaling pathway
epz04360
Axon guidance
epz04510
Focal adhesion
epz04520
Adherens junction
epz05100
Bacterial invasion of epithelial cells
epz05144
Malaria
epz05200
Pathways in cancer
epz05202
Transcriptional misregulation in cancer
epz05205
Proteoglycans in cancer
epz05206
MicroRNAs in cancer
epz05208
Chemical carcinogenesis - reactive oxygen species
epz05211
Renal cell carcinoma
epz05218
Melanoma
epz05223
Non-small cell lung cancer
epz05225
Hepatocellular carcinoma
epz05226
Gastric cancer
epz05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
epz00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103562070 (MET)
04014 Ras signaling pathway
103562070 (MET)
04015 Rap1 signaling pathway
103562070 (MET)
04020 Calcium signaling pathway
103562070 (MET)
04151 PI3K-Akt signaling pathway
103562070 (MET)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
103562070 (MET)
04520 Adherens junction
103562070 (MET)
09150 Organismal Systems
09158 Development and regeneration
04360 Axon guidance
103562070 (MET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103562070 (MET)
05202 Transcriptional misregulation in cancer
103562070 (MET)
05206 MicroRNAs in cancer
103562070 (MET)
05205 Proteoglycans in cancer
103562070 (MET)
05208 Chemical carcinogenesis - reactive oxygen species
103562070 (MET)
05230 Central carbon metabolism in cancer
103562070 (MET)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
103562070 (MET)
05226 Gastric cancer
103562070 (MET)
05218 Melanoma
103562070 (MET)
05211 Renal cell carcinoma
103562070 (MET)
05223 Non-small cell lung cancer
103562070 (MET)
09171 Infectious disease: bacterial
05100 Bacterial invasion of epithelial cells
103562070 (MET)
09174 Infectious disease: parasitic
05144 Malaria
103562070 (MET)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103562070 (MET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
epz01001
]
103562070 (MET)
Enzymes [BR:
epz01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
103562070 (MET)
Protein kinases [BR:
epz01001
]
Receptor tyrosine kinases (RTK)
MET family
103562070 (MET)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
TIG
Pkinase
Sema
Kinase-like
Pkinase_fungal
Linker_histone
Motif
Other DBs
NCBI-GeneID:
103562070
NCBI-ProteinID:
XP_008535230
LinkDB
All DBs
Position
Un
AA seq
1415 aa
AA seq
DB search
MLPLAAVSSRMHIVSPKTDRATFPVKDKLLTMKAPAVLAPGILVLLFTLVQKSDGECKEA
LVKSEMNVNMKYQLPNFTAETPIQNVVLHKHHIYLGATNYIYVLNDKDLQKVAEYKTGPV
LEHPDCFPCQDCSRKANLSGGAWKDNINMALLVDTYYDDQLISCGSVHRGTCQRHVLPLN
NVADIQSEVYCMYSPQAEEPHQCPDCVVSALGTKVLLSEKDRFVTFFVGNTINSSYLPDH
SLHSISVRRLKETQDGFKFLTDQSYIDVLPEFRDSYPIKYIHAFESNHFIYFLTVQRETL
DAQTFHTRIIRFCSVDSGLHSYMEMPLECILTEKRRKRSTSEEVFNILQAAYVSKPGAHL
AKQIGANLNDDILYGVFAQSKPDSAEPMNRSAVCAFPVKYVNEFFNKIVNKNNVRCLQHF
YGPHHEHCFNRTLLRNSSGCEVRNDEYRTEFTTALQRVDLFMGQFNQVLLTSISTFIKGN
LTIANLGTSEGRFMQVVVSRSGSSTPHVNFHLDSHPVSPEVIVEHPLNQNGYTLVVTGKK
ITKIPLNGLGCEHFQSCSQCLSAXXXXXXXXXXXXXDKCVRLEECHNRTWTQEICLPTIY
KVFPTSAPLEGGTTLTVCGWDFGFRKNNKLDSKKTKVLLGNESCTLTLSESTSNTLKCTV
GPAMNERFNISITVSNSRGTARYSTFSYVDPIITSISPSYGPKTGGTLLTLTGKYLNSGN
SRHISIGGKTCTLKSVSDSILECYTPAQTTPTEFPVKLKIDLANREMNSFSYREDPIVYE
IHPTKSFISGGSTITGVGKNLNSVSVLRMVINVREAGRNFTVACQHRSNSEIICCTTPSL
QQLNLQLPLKTKAFFMLDGIHSKYFDLIYVHNPVFKPFEKPVMISIGNENVLEIKGNDID
PEAVKGEVLKVGNKSCENIHSHSEAVLCTVPSDLLKLNSELNIEWKQAVSSTILGKVIVQ
PDQNFTGLIVGVVSISIILLLLLGLFLWLKRRKQIKDLGSELVRYDARVHTPHLDRLVSA
RSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGSCRQVQYPLTDLSPILTSGDSDISSPL
LQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDDKKIH
CAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLR
NFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLA
RDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPD
VNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISAIFSTFIG
EHYVHVNATYVNVKCVAPYPSLLSSQDNVDGEVDT
NT seq
4248 nt
NT seq
+upstream
nt +downstream
nt
atgcttccacttgctgctgtctcatccaggatgcatattgtctcacccaagaccgatcgt
gccactttcccagttaaggataaacttctcaccatgaaggcacctgctgtgcttgcacct
ggcatccttgtgcttctgtttaccttggtgcagaagagcgatggggagtgtaaagaggcg
ctagtaaagtccgagatgaatgtgaacatgaagtatcagcttcccaacttcactgcagaa
acacccatccagaacgtcgttttacacaagcatcacatttacctcggggccactaactac
atttatgttttaaatgacaaagatcttcagaaagttgctgagtacaagactgggcccgtg
ctggaacacccagattgtttcccatgtcaggactgcagccgcaaagccaatttatcaggt
ggcgcttggaaagataacatcaacatggctctgcttgttgacacatactatgacgatcaa
ctcattagttgcggcagcgtccacagagggacctgccagcggcacgtccttccactcaac
aatgttgctgacatacagtcagaagtttattgcatgtactctccacaagcagaagagccc
caccagtgtcctgactgtgtggtgagtgccctgggaaccaaagtcctgctgtctgaaaag
gaccgatttgtcaccttcttcgtgggcaataccataaattcttcttaccttccagatcat
tcattgcattcgatatcggtgagaaggctaaaggaaacgcaagatggttttaagtttttg
acagatcagtcctatattgatgttctacctgagttccgagattcttaccccattaagtat
atccacgcctttgaaagcaaccattttatttactttttaacggtccaacgggaaactcta
gatgctcagacttttcacacaagaataatcaggttctgttccgtggactctggattgcat
tcctacatggaaatgcctctggagtgtattctcacagaaaagagaagaaagagatccaca
agtgaggaagtgtttaatatcctccaagctgcgtatgtcagtaagcctggggctcatctt
gctaagcaaataggtgccaacctgaatgatgacattctctatggggtgtttgcacagagc
aagccagattctgctgaaccaatgaatcgctctgccgtctgtgcattccctgtcaaatat
gtcaatgaattcttcaacaagattgtcaacaaaaacaacgtgagatgtctccagcatttt
tatggaccccaccatgaacactgcttcaataggacacttttgagaaattcatcaggctgt
gaagtgcgcaatgatgaatatcgaacggagtttaccacagctttgcagcgcgttgacttg
ttcatgggccaattcaaccaagtcctcttgacatctatatccaccttcattaaaggaaac
ctcactatagctaatcttgggacatcagaaggtcgcttcatgcaggttgtggtttctcga
tcaggatcgtcaacccctcatgtgaattttcacctggattcccaccctgtgtctccagaa
gtgattgtggaacacccattaaaccaaaatggttacacactggttgtcaccgggaaaaag
atcaccaagatcccactgaatggcttgggctgtgaacatttccagtcctgcagtcagtgt
ctctccgcnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnngacaaatgtgtg
cgattggaggaatgccacaacagaacatggactcaagagatctgtctgcctacaatctac
aaggttttcccaaccagtgcccccctcgaaggagggacaacgctgacagtatgtggctgg
gactttggattcaggaagaataataaacttgattcaaagaaaaccaaagttctccttgga
aatgagagctgcaccttgactttaagtgagagcacgtcaaatacgttgaaatgcacagtt
ggtcctgcaatgaatgagcgtttcaatatatccataactgtttccaacagtcgagggaca
gcacgatatagtacattttcctatgtggatcctataataacaagtatttctccaagttat
ggtcctaagactggtggcactttacttactttaactggaaagtacttaaacagtgggaat
tctagacacatttcaattggtggaaaaacatgtaccttaaaaagtgtgtcagatagtatt
cttgaatgttatactccagcccaaaccactccaactgagtttcccgttaaactgaaaatt
gacttagccaaccgagagatgaacagcttcagttaccgggaagaccccattgtctatgaa
attcatccaaccaaatcttttattagtggtgggagcacaattacaggtgttggaaaaaat
ctgaattcggttagtgtcctgaggatggtgataaatgtgcgtgaagcaggaaggaacttt
acagtggcatgtcagcatcgctctaattcagagataatctgctgtacaactccttcacta
caacagctgaatttgcaactccctctgaaaaccaaagccttcttcatgttggacgggatc
cattccaaatactttgatctcatttatgtacataatcctgtgtttaagccttttgaaaag
ccagtgatgatctcaataggcaatgaaaatgtactggaaattaagggaaatgatattgac
cctgaagccgttaaaggtgaagtgttaaaagttggaaataagagctgtgagaatatacac
tcacattctgaagccgttttatgtacagtccccagtgacctgctgaaattgaacagcgag
ctaaatatagagtggaagcaagcagtttcttcaaccatccttggaaaagtaatagttcaa
ccagatcagaatttcacaggattgattgttggtgttgtctcaatatcaataatactctta
ttattactcgggcttttcctgtggctgaaaaggagaaagcaaattaaagatctgggcagt
gaattagttcgctatgatgcaagagtacacactcctcatttggataggcttgtaagtgcc
cgaagtgtaagcccaactacagaaatggtttcaaatgaatctgtagactaccgagctact
tttccagaagaccagtttcctaactcatctcagaatggatcatgcagacaagtgcagtat
cctctgacggacctatcccccatcctaactagtggggactctgatatatccagtccatta
ctgcaaaataccgtccacattgacctcagtgctctaaatccagagctggtgcaggcagtc
cagcacgtagtgattgggcctagtagtctgattgtgcatttcaatgaagtcataggaaga
ggacattttgggtgtgtatatcatgggactttgttggacaatgatgacaagaaaattcac
tgtgctgtgaaatccttgaatagaatcactgacataggagaagtttcccagtttctcacc
gagggaattatcatgaaagattttagtcatcccaacgttctctcgctcttgggaatctgc
cttcgaagtgagggatctccactggtggttctaccgtacatgaaacatggagaccttcga
aatttcattagaaatgagacccacaacccaactgtaaaagatcttattggctttggtctt
caagtagccaaaggcatgaaatatcttgcaagcaaaaagtttgtccacagagacttggct
gcaagaaactgtatgctggatgaaaaattcactgtcaaggttgctgattttgggcttgcc
agagacatgtatgataaagaatactatagtgtgcacaacaaaacaggtgcaaaactgcct
gtgaagtggatggctttagagagtctgcaaactcagaagtttaccaccaagtcagatgtg
tggtcctttggcgtgctcctctgggagctgatgacaagaggagcaccaccttatcccgat
gtcaacacctttgatataacagtttacttgttgcaaggcagaaggctcttacaaccagag
tactgcccagatcccttgtatgaagtgatgctaaaatgctggcaccctaaagctgaactg
cgcccatccttttctgaactggtctccaggatatcagcgatattctctactttcatcggg
gagcactacgtccatgtgaacgctacttatgtgaatgtgaaatgtgttgctccatatcct
tctctgttgtcatcacaagataacgttgatggcgaggtagatacatga
DBGET
integrated database retrieval system