Svoboda
|
Graniru
|
BBC Russia
|
Golosameriki
|
Facebook
Felis catus (domestic cat): 101092346
Help
Entry
101092346 CDS
T02385
Symbol
BRAF
Name
(RefSeq) serine/threonine-protein kinase B-raf isoform X5
KO
K04365
B-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca01521
EGFR tyrosine kinase inhibitor resistance
fca01522
Endocrine resistance
fca04010
MAPK signaling pathway
fca04012
ErbB signaling pathway
fca04015
Rap1 signaling pathway
fca04024
cAMP signaling pathway
fca04062
Chemokine signaling pathway
fca04068
FoxO signaling pathway
fca04150
mTOR signaling pathway
fca04270
Vascular smooth muscle contraction
fca04510
Focal adhesion
fca04650
Natural killer cell mediated cytotoxicity
fca04720
Long-term potentiation
fca04722
Neurotrophin signaling pathway
fca04726
Serotonergic synapse
fca04730
Long-term depression
fca04810
Regulation of actin cytoskeleton
fca04910
Insulin signaling pathway
fca04914
Progesterone-mediated oocyte maturation
fca04928
Parathyroid hormone synthesis, secretion and action
fca04934
Cushing syndrome
fca05010
Alzheimer disease
fca05022
Pathways of neurodegeneration - multiple diseases
fca05034
Alcoholism
fca05160
Hepatitis C
fca05161
Hepatitis B
fca05200
Pathways in cancer
fca05205
Proteoglycans in cancer
fca05208
Chemical carcinogenesis - reactive oxygen species
fca05210
Colorectal cancer
fca05211
Renal cell carcinoma
fca05212
Pancreatic cancer
fca05213
Endometrial cancer
fca05214
Glioma
fca05215
Prostate cancer
fca05216
Thyroid cancer
fca05218
Melanoma
fca05219
Bladder cancer
fca05220
Chronic myeloid leukemia
fca05221
Acute myeloid leukemia
fca05223
Non-small cell lung cancer
fca05224
Breast cancer
fca05225
Hepatocellular carcinoma
fca05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101092346 (BRAF)
04012 ErbB signaling pathway
101092346 (BRAF)
04015 Rap1 signaling pathway
101092346 (BRAF)
04068 FoxO signaling pathway
101092346 (BRAF)
04024 cAMP signaling pathway
101092346 (BRAF)
04150 mTOR signaling pathway
101092346 (BRAF)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
101092346 (BRAF)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101092346 (BRAF)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
101092346 (BRAF)
04062 Chemokine signaling pathway
101092346 (BRAF)
09152 Endocrine system
04910 Insulin signaling pathway
101092346 (BRAF)
04914 Progesterone-mediated oocyte maturation
101092346 (BRAF)
04928 Parathyroid hormone synthesis, secretion and action
101092346 (BRAF)
09153 Circulatory system
04270 Vascular smooth muscle contraction
101092346 (BRAF)
09156 Nervous system
04726 Serotonergic synapse
101092346 (BRAF)
04720 Long-term potentiation
101092346 (BRAF)
04730 Long-term depression
101092346 (BRAF)
04722 Neurotrophin signaling pathway
101092346 (BRAF)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101092346 (BRAF)
05205 Proteoglycans in cancer
101092346 (BRAF)
05208 Chemical carcinogenesis - reactive oxygen species
101092346 (BRAF)
09162 Cancer: specific types
05210 Colorectal cancer
101092346 (BRAF)
05212 Pancreatic cancer
101092346 (BRAF)
05225 Hepatocellular carcinoma
101092346 (BRAF)
05226 Gastric cancer
101092346 (BRAF)
05214 Glioma
101092346 (BRAF)
05216 Thyroid cancer
101092346 (BRAF)
05221 Acute myeloid leukemia
101092346 (BRAF)
05220 Chronic myeloid leukemia
101092346 (BRAF)
05218 Melanoma
101092346 (BRAF)
05211 Renal cell carcinoma
101092346 (BRAF)
05219 Bladder cancer
101092346 (BRAF)
05215 Prostate cancer
101092346 (BRAF)
05213 Endometrial cancer
101092346 (BRAF)
05224 Breast cancer
101092346 (BRAF)
05223 Non-small cell lung cancer
101092346 (BRAF)
09172 Infectious disease: viral
05161 Hepatitis B
101092346 (BRAF)
05160 Hepatitis C
101092346 (BRAF)
09164 Neurodegenerative disease
05010 Alzheimer disease
101092346 (BRAF)
05022 Pathways of neurodegeneration - multiple diseases
101092346 (BRAF)
09165 Substance dependence
05034 Alcoholism
101092346 (BRAF)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
101092346 (BRAF)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101092346 (BRAF)
01522 Endocrine resistance
101092346 (BRAF)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
fca01001
]
101092346 (BRAF)
Enzymes [BR:
fca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101092346 (BRAF)
Protein kinases [BR:
fca01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
101092346 (BRAF)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
ABC1
C1_2
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
101092346
NCBI-ProteinID:
XP_006929486
UniProt:
A0A2I2ULH6
LinkDB
All DBs
Position
A2:complement(155188171..155347774)
Genome browser
AA seq
764 aa
AA seq
DB search
MAALSGGGGGGGAEQGQALFNGDMEPEAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEA
LLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLGNGTDFSVSSSASTDTVTSS
SSSSLSVLPSSLSVFQNPTDVSRSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKK
ALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFF
TLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQE
EASIAETALTSGSSPSAPPSDSTGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQRDRS
SSAPNVHINTIEPVNIDDLIRDQGFRSDGGSTTGLSATPPASLPGSLTNVKALQKSPGPQ
RERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVK
MLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHI
IETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSR
WSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRD
QIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPK
IHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGEFAAFK
NT seq
2295 nt
NT seq
+upstream
nt +downstream
nt
atggcggcgctgagcggcggcggcggcggcggtggcgcggagcagggccaggctctgttc
aacggggacatggagcccgaagccggcgccgcggcctcttcggctgcggaccctgccatt
cccgaggaggtgtggaatatcaaacaaatgattaagttgacacaggaacatatagaggcc
ctattggacaaatttggtggggagcataatccaccatcaatatatctagaggcctatgaa
gaatacaccagcaagctagatgccctccaacagagagaacaacagttattggaatccctg
gggaatggaactgatttttctgtttctagctctgcatcaacggacaccgttacatcttcc
tcctcttctagcctttcagtgctaccttcatctctttcagtttttcaaaaccccacagat
gtgtcacggagcaatcccaagtcaccacagaaacctatcgttagagtcttcctgcctaat
aaacagaggacagtggtacctgcaagatgtggagttacagtccgggacagtctaaagaaa
gctctgatgatgagaggtctaatccctgagtgctgtgctgtttacagaattcaggatgga
gagaagaaaccaattggctgggacactgatatctcctggctcaccggagaggaattgcat
gtagaagtgttggaaaatgttccacttacaactcacaactttgtacggaaaacgtttttc
accttagcattttgtgacttttgtcgaaagctgcttttccaaggttttcgctgtcaaacg
tgtggttataaatttcaccagcgttgtagtacagaggttccactgatgtgtgttaattat
gaccaacttgatttgctgtttgtctccaagttctttgaacaccacccaataccacaggag
gaggcctccatagcagagactgccctaacgtctggatcgtccccttctgcccccccctcc
gattctactgggccccaaattctcaccagtccgtctccttcaaaatccattccaattcca
cagcctttccgaccagcagatgaagatcatcgaaatcaatttggacagcgagaccggtcc
tcatcagctccaaatgtgcatataaatacaatagaacctgtcaatattgatgacttgatt
agagaccaggggtttcgtagtgatggaggatcaaccacaggcttgtctgccaccccccct
gcctcattgccgggctctctcactaatgtaaaagcattacagaaatctccagggcctcag
cgggaaaggaaatcttcttcatcctcagaagataggaatcgaatgaaaacacttggtaga
agggattcaagtgatgattgggagattcctgatgggcagatcacagtgggacagagaatt
ggatccgggtcatttgggacagtctacaagggaaagtggcatggtgatgtggcagtgaaa
atgttgaatgtgacagcacccacacctcagcagttacaggccttcaaaaatgaagtagga
gtactcaggaaaactcggcatgtgaacatcctgctcttcatgggctattcaacaaagccc
cagctggctattgtcacccagtggtgtgagggctccagcttataccaccatctccacatc
atcgagaccaaattcgagatgatcaagctgatagatattgctcggcagactgcgcagggc
atggattacttacacgccaagtcaatcatccacagagacctcaagagtaataatattttt
cttcacgaagacctcacagtaaaaataggtgattttggtctagccacagtgaaatctcga
tggagtgggtcccatcagtttgaacagttgtctggatccattttgtggatggcaccagaa
gtaattcgaatgcaagataaaaacccatatagctttcagtcagatgtatatgcatttggg
attgttctatatgaattgatgactggacagttaccttattcaaacatcaacaacagggac
cagataatttttatggtgggacgaggatatctttctccagatctcagtaaggtacgaagt
aactgtccgaaagccatgaagagattgatggcagagtgcctaaaaaagaaaagagatgag
aggccactgtttccccaaattcttgcctctattgagctgctggcccgctcattgccaaaa
attcaccgcagtgcatcagaaccctccttgaatcgggctggcttccagacagaggatttt
agtctctatgcttgtgcttctccaaaaacacccatccaggcagggggatatggagaattt
gcagccttcaagtag
DBGET
integrated database retrieval system