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Homo sapiens (human): 2557
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Entry
2557 CDS
T01001
Symbol
GABRA4
Name
(RefSeq) gamma-aminobutyric acid type A receptor subunit alpha4
KO
K05175
gamma-aminobutyric acid receptor subunit alpha
Organism
hsa
Homo sapiens (human)
Pathway
hsa04080
Neuroactive ligand-receptor interaction
hsa04723
Retrograde endocannabinoid signaling
hsa04727
GABAergic synapse
hsa04742
Taste transduction
hsa05032
Morphine addiction
hsa05033
Nicotine addiction
Drug target
Abecarnil:
D02594
Adinazolam (
DG00911
):
D02770
D02771
Adipiplon:
D08840
Alpidem:
D02833
Alprazolam:
D00225
<JP/US>
Aminobutyric acid:
D00058
<JP>
Amobarbital (
DG00916
):
D00555
D02252
Aprobarbital:
D00698
Barbexaclone:
D07298
Barbital:
D01740
Bretazenil:
D03155
Brexanolone:
D11149
<US>
Bromazepam:
D01245
<JP>
Brotizolam:
D01744
<JP>
Butabarbital (
DG01308
):
D00699
D03180
Butobarbital:
D02618
Cenobamate:
D11150
<US>
Chlordiazepoxide (
DG00908
):
D00267
<JP>
D00693
<US>
Cinolazepam:
D07328
Cipepofol:
D12449
Clobazam:
D01253
<JP/US>
Clonazepam:
D00280
<JP/US>
Clotiazepam:
D01328
<JP>
Cloxazolam:
D01268
<JP>
Darigabat:
D12146
Delorazepam:
D07784
Dextofisopam:
D03737
Diazepam:
D00293
<JP/US>
Estazolam:
D00311
<JP/US>
Eszopiclone:
D02624
<JP/US>
Ethyl loflazepate:
D01293
<JP>
Etizolam:
D01514
<JP>
Fludiazepam:
D01354
Flumazenil:
D00697
<JP/US>
Flunitrazepam:
D01230
<JP>
Flurazepam (
DG00919
):
D00329
D00695
<US>
D01408
<JP>
Flutazolam:
D01286
<JP>
Flutoprazepam:
D01279
Gaboxadol:
D04282
Ganaxolone:
D04300
<US>
Glutethimide:
D00532
Halazepam:
D00338
Haloxazolam:
D01758
<JP>
Hexobarbital:
D01071
Indiplon:
D02640
Iomazenil:
D02283
<JP>
Ketazolam:
D04650
Levotofisopam:
D04721
Loprazolam (
DG00921
):
D07326
D08145
Lorazepam:
D00365
<JP/US>
Lormetazepam:
D01657
<JP>
Medazepam (
DG00909
):
D01292
<JP>
D04882
Meprobamate:
D00376
<US>
Metharbital:
D01382
Methylphenobarbital:
D00700
Mexazolam:
D01316
<JP>
Midazolam (
DG00920
):
D00550
<JP/US>
D00696
<US>
D05028
Nimetazepam:
D01593
Nitrazepam:
D00531
<JP>
Nordazepam:
D08283
Ocinaplon:
D02617
Oxazepam:
D00464
<US>
Oxazolam:
D01278
<JP>
Pagoclone:
D02616
Panadiplon:
D05346
Pazinaclone:
D05378
Pentobarbital (
DG00915
):
D00499
D00500
<US>
D02253
<JP>
Phenobarbital (
DG00845
):
D00506
<JP>
D00701
<JP/US>
D08356
Potassium clorazepate (
DG01218
):
D00694
<JP/US>
D03562
Prazepam:
D00470
Propofol (
DG00797
):
D00549
<JP/US>
D04257
Quazepam:
D00457
<JP/US>
Remimazolam (
DG03105
):
D10194
<JP/US>
D11788
Rilmazafone (
DG01307
):
D01564
<JP>
D08481
Sarmazenil:
D08507
Secobarbital (
DG00917
):
D00430
D01310
Suritozole:
D05980
Talbutal:
D06887
Temazepam:
D00370
<US>
Thiamylal (
DG01377
):
D00713
<JP>
D06106
Thiopental (
DG00790
):
D00714
<JP>
Tofisopam:
D01254
<JP>
Topiramate:
D00537
<JP/US>
Triazolam:
D00387
<JP/US>
Zolpidem (
DG00922
):
D00706
<JP/US>
D08690
Zopiclone:
D01372
<JP>
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
2557 (GABRA4)
09150 Organismal Systems
09156 Nervous system
04727 GABAergic synapse
2557 (GABRA4)
04723 Retrograde endocannabinoid signaling
2557 (GABRA4)
09157 Sensory system
04742 Taste transduction
2557 (GABRA4)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
2557 (GABRA4)
05033 Nicotine addiction
2557 (GABRA4)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
hsa04040
]
2557 (GABRA4)
Ion channels [BR:
hsa04040
]
Ligand-gated channels
GABA-A
2557 (GABRA4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Neur_chan_memb
Neur_chan_LBD
OAD_gamma
Motif
Other DBs
NCBI-GeneID:
2557
NCBI-ProteinID:
NP_000800
OMIM:
137141
HGNC:
4078
Ensembl:
ENSG00000109158
UniProt:
P48169
X5D7F5
Structure
PDB
LinkDB
All DBs
Position
4:complement(46918900..46993581)
Genome browser
AA seq
554 aa
AA seq
DB search
MVSAKKVPAIALSAGVSFALLRFLCLAVCLNESPGQNQKEEKLCTENFTRILDSLLDGYD
NRLRPGFGGPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKRLKYDGPIEILRLN
NMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTISAECPMRLVDFP
MDGHACPLKFGSYAYPKSEMIYTWTKGPEKSVEVPKESSSLVQYDLIGQTVSSETIKSIT
GEYIVMTVYFHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPARTVFGITTVLTMT
TLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNIQMEKAKRKTSKPPQ
EVPAAPVQREKHPEAPLQNTNANLNMRKRTNALVHSESDVGNRTEVGNHSSKSSTVVQES
SKGTPRSYLASSPNPFSRANAAETISAARALPSASPTSIRTGYMPRKASVGSASTRHVFG
SRLQRIKTTVNTIGATGKLSATPPPSAPPPSGSGTSKIDKYARILFPVTFGAFNMVYWVV
YLSKDTMEKSESLM
NT seq
1665 nt
NT seq
+upstream
nt +downstream
nt
atggtttctgccaagaaggtacccgcgatcgctctgtccgccggggtcagtttcgccctc
ctgcgcttcctgtgcctggcggtttgtttaaacgaatccccaggacagaaccaaaaggag
gagaaattgtgcacagaaaatttcacccgcatcctggacagtttgctcgatggttatgac
aacaggctgcgtcctggatttgggggtcctgttacagaagtgaaaactgacatatatgtc
accagctttggacctgtttctgatgttgaaatggaatacacaatggatgtgttcttcagg
cagacatggattgacaaaagattaaaatatgacggccccattgaaattttgagattgaac
aatatgatggtaacgaaagtgtggacccctgatactttcttcaggaatggaaagaaatct
gtctcacataatatgacagctccaaataagctttttagaattatgagaaatggtactatt
ttatacacaatgagactcaccataagtgcggagtgtcccatgagattggtggattttccc
atggatggtcatgcatgccctttgaaattcgggagttatgcctatccaaagagtgagatg
atctatacctggacaaaaggtcctgagaaatcagttgaagttccgaaggagtcttccagc
ttagttcaatatgatttgattgggcaaaccgtatcaagtgaaaccatcaaatcaattacg
ggtgaatatattgttatgacggtttacttccacctcagacggaagatgggttattttatg
attcagacctatattccgtgcattatgacagtgattctttctcaagtttcattttggata
aataaagaatcagttcccgctaggactgtatttggaataacaactgtcctcaccatgacc
acactaagcatcagtgcacgacattctttgcccaaagtgtcctatgctaccgccatggac
tggttcatagctgtctgctttgcttttgtattttcggcccttatcgagtttgctgctgtc
aactatttcaccaatattcaaatggaaaaagccaaaaggaagacatcaaagccccctcag
gaagttcccgctgctccagtgcagagagagaagcatcctgaagcccctctgcagaataca
aatgccaatttgaacatgagaaaaagaacaaatgctttggttcactctgaatctgatgtt
ggcaacagaactgaggtgggaaaccattcaagcaaatcttccacagttgttcaagaatct
tctaaaggcacacctcggtcttacttagcttccagtccaaacccattcagccgtgcaaat
gcagctgaaaccatatctgcagcaagagcacttccatctgcttctcctacttctatccga
actggatatatgcctcgaaaggcttcagttggatctgcttctactcgtcacgtgtttgga
tcaagactgcagaggataaagaccacagttaataccataggggctactgggaagttgtca
gctactcctcctccatcggctccaccaccttctggatctggcacaagtaaaatagacaaa
tatgcccgtattctctttccagtcacatttggggcatttaacatggtttattgggttgtt
tatttatctaaggacactatggagaaatcagaaagtctaatgtaa
DBGET
integrated database retrieval system