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Homo sapiens (human): 2568
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Entry
2568 CDS
T01001
Symbol
GABRP
Name
(RefSeq) gamma-aminobutyric acid type A receptor subunit pi
KO
K05189
gamma-aminobutyric acid receptor subunit pi
Organism
hsa
Homo sapiens (human)
Pathway
hsa04080
Neuroactive ligand-receptor interaction
hsa04723
Retrograde endocannabinoid signaling
hsa04727
GABAergic synapse
hsa05032
Morphine addiction
hsa05033
Nicotine addiction
Drug target
Abecarnil:
D02594
Adinazolam (
DG00911
):
D02770
D02771
Adipiplon:
D08840
Alpidem:
D02833
Alprazolam:
D00225
<JP/US>
Aminobutyric acid:
D00058
<JP>
Amobarbital (
DG00916
):
D00555
D02252
Aprobarbital:
D00698
Barbexaclone:
D07298
Barbital:
D01740
Bretazenil:
D03155
Brexanolone:
D11149
<US>
Bromazepam:
D01245
<JP>
Brotizolam:
D01744
<JP>
Butabarbital (
DG01308
):
D00699
D03180
Butobarbital:
D02618
Cenobamate:
D11150
<US>
Chlordiazepoxide (
DG00908
):
D00267
<JP>
D00693
<US>
Cinolazepam:
D07328
Cipepofol:
D12449
Clobazam:
D01253
<JP/US>
Clonazepam:
D00280
<JP/US>
Clotiazepam:
D01328
<JP>
Cloxazolam:
D01268
<JP>
Darigabat:
D12146
Delorazepam:
D07784
Dextofisopam:
D03737
Diazepam:
D00293
<JP/US>
Estazolam:
D00311
<JP/US>
Eszopiclone:
D02624
<JP/US>
Ethyl loflazepate:
D01293
<JP>
Etizolam:
D01514
<JP>
Fludiazepam:
D01354
Flumazenil:
D00697
<JP/US>
Flunitrazepam:
D01230
<JP>
Flurazepam (
DG00919
):
D00329
D00695
<US>
D01408
<JP>
Flutazolam:
D01286
<JP>
Flutoprazepam:
D01279
Gaboxadol:
D04282
Ganaxolone:
D04300
<US>
Glutethimide:
D00532
Halazepam:
D00338
Haloxazolam:
D01758
<JP>
Hexobarbital:
D01071
Indiplon:
D02640
Iomazenil:
D02283
<JP>
Ketazolam:
D04650
Levotofisopam:
D04721
Loprazolam (
DG00921
):
D07326
D08145
Lorazepam:
D00365
<JP/US>
Lormetazepam:
D01657
<JP>
Medazepam (
DG00909
):
D01292
<JP>
D04882
Meprobamate:
D00376
<US>
Metharbital:
D01382
Methylphenobarbital:
D00700
Mexazolam:
D01316
<JP>
Midazolam (
DG00920
):
D00550
<JP/US>
D00696
<US>
D05028
Nimetazepam:
D01593
Nitrazepam:
D00531
<JP>
Nordazepam:
D08283
Ocinaplon:
D02617
Oxazepam:
D00464
<US>
Oxazolam:
D01278
<JP>
Pagoclone:
D02616
Panadiplon:
D05346
Pazinaclone:
D05378
Pentobarbital (
DG00915
):
D00499
D00500
<US>
D02253
<JP>
Phenobarbital (
DG00845
):
D00506
<JP>
D00701
<JP/US>
D08356
Potassium clorazepate (
DG01218
):
D00694
<JP/US>
D03562
Prazepam:
D00470
Propofol (
DG00797
):
D00549
<JP/US>
D04257
Quazepam:
D00457
<JP/US>
Remimazolam (
DG03105
):
D10194
<JP/US>
D11788
Rilmazafone (
DG01307
):
D01564
<JP>
D08481
Sarmazenil:
D08507
Secobarbital (
DG00917
):
D00430
D01310
Suritozole:
D05980
Talbutal:
D06887
Temazepam:
D00370
<US>
Thiamylal (
DG01377
):
D00713
<JP>
D06106
Thiopental (
DG00790
):
D00714
<JP>
Tofisopam:
D01254
<JP>
Topiramate:
D00537
<JP/US>
Triazolam:
D00387
<JP/US>
Zolpidem (
DG00922
):
D00706
<JP/US>
D08690
Zopiclone:
D01372
<JP>
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
2568 (GABRP)
09150 Organismal Systems
09156 Nervous system
04727 GABAergic synapse
2568 (GABRP)
04723 Retrograde endocannabinoid signaling
2568 (GABRP)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
2568 (GABRP)
05033 Nicotine addiction
2568 (GABRP)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
hsa04040
]
2568 (GABRP)
Ion channels [BR:
hsa04040
]
Ligand-gated channels
GABA-A
2568 (GABRP)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Neur_chan_LBD
Neur_chan_memb
Motif
Other DBs
NCBI-GeneID:
2568
NCBI-ProteinID:
NP_055026
OMIM:
602729
HGNC:
4089
Ensembl:
ENSG00000094755
UniProt:
O00591
LinkDB
All DBs
Position
5:170782720..170814047
Genome browser
AA seq
440 aa
AA seq
DB search
MNYSLHLAFVCLSLFTERMCIQGSQFNVEVGRSDKLSLPGFENLTAGYNKFLRPNFGGEP
VQIALTLDIASISSISESNMDYTATIYLRQRWMDQRLVFEGNKSFTLDARLVEFLWVPDT
YIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVACNMDLSKYPMDTQTCKLQLES
WGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERYFTLVTRSQQETGNYTRLVLQFELRR
NVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCIGVTTVLSMTTLMIGSRTSLPNTN
CFIKAIDVYLGICFSFVFGALLEYAVAHYSSLQQMAAKDRGTTKEVEEVSITNIINSSIS
SFKRKISFASIEISSDNVDYSDLTMKTSDKFKFVFREKMGRIVDYFTIQNPSNVDHYSKL
LFPLIFMLANVFYWAYYMYF
NT seq
1323 nt
NT seq
+upstream
nt +downstream
nt
atgaactacagcctccacttggccttcgtgtgtctgagtctcttcactgagaggatgtgc
atccaggggagtcagttcaacgtcgaggtcggcagaagtgacaagctttccctgcctggc
tttgagaacctcacagcaggatataacaaatttctcaggcccaattttggtggagaaccc
gtacagatagcgctgactctggacattgcaagtatctctagcatttcagagagtaacatg
gactacacagccaccatatacctccgacagcgctggatggaccagcggctggtgtttgaa
ggcaacaagagcttcactctggatgcccgcctcgtggagttcctctgggtgccagatact
tacattgtggagtccaagaagtccttcctccatgaagtcactgtgggaaacaggctcatc
cgcctcttctccaatggcacggtcctgtatgccctcagaatcacgacaactgttgcatgt
aacatggatctgtctaaataccccatggacacacagacatgcaagttgcagctggaaagc
tggggctatgatggaaatgatgtggagttcacctggctgagagggaacgactctgtgcgt
ggactggaacacctgcggcttgctcagtacaccatagagcggtatttcaccttagtcacc
agatcgcagcaggagacaggaaattacactagattggtcttacagtttgagcttcggagg
aatgttctgtatttcattttggaaacctacgttccttccactttcctggtggtgttgtcc
tgggtttcattttggatctctctcgattcagtccctgcaagaacctgcattggagtgacg
accgtgttatcaatgaccacactgatgatcgggtcccgcacttctcttcccaacaccaac
tgcttcatcaaggccatcgatgtgtacctggggatctgctttagctttgtgtttggggcc
ttgctagaatatgcagttgctcactacagttccttacagcagatggcagccaaagatagg
gggacaacaaaggaagtagaagaagtcagtattactaatatcatcaacagctccatctcc
agctttaaacggaagatcagctttgccagcattgaaatttccagcgacaacgttgactac
agtgacttgacaatgaaaaccagcgacaagttcaagtttgtcttccgagaaaagatgggc
aggattgttgattatttcacaattcaaaaccccagtaatgttgatcactattccaaacta
ctgtttcctttgatttttatgctagccaatgtattttactgggcatactacatgtatttt
tga
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integrated database retrieval system