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KEGG   VARIANT: 10v1
Entry
10v1                      Variant                                  
Name
NAT2 polymorphism for poor drug metabolism
Gene
NAT2  N-acetyltransferase 2 [KO:K00622]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
*5 mutation I114T
ClinVar: 723
dbSNP: rs1801280
Reference
  Authors
Butcher NJ, Boukouvala S, Sim E, Minchin RF
  Title
Pharmacogenetics of the arylamine N-acetyltransferases.
  Journal
Pharmacogenomics J 2:30-42 (2002)
DOI:10.1038/sj.tpj.6500053
Reference
  Authors
Soejima M, Sugiura T, Kawaguchi Y, Kawamoto M, Katsumata Y, Takagi K, Nakajima A, Mitamura T, Mimori A, Hara M, Kamatani N
  Title
Association of the diplotype configuration at the N-acetyltransferase 2 gene with adverse events with co-trimoxazole in Japanese patients with systemic lupus erythematosus.
  Journal
Arthritis Res Ther 9:R23 (2007)
DOI:10.1186/ar2134
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