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Macaca mulatta (rhesus monkey): 693554
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Entry
693554 CDS
T01028
Symbol
BRAF
Name
(RefSeq) serine/threonine-protein kinase B-raf isoform X1
KO
K04365
B-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc01521
EGFR tyrosine kinase inhibitor resistance
mcc01522
Endocrine resistance
mcc04010
MAPK signaling pathway
mcc04012
ErbB signaling pathway
mcc04015
Rap1 signaling pathway
mcc04024
cAMP signaling pathway
mcc04062
Chemokine signaling pathway
mcc04068
FoxO signaling pathway
mcc04150
mTOR signaling pathway
mcc04270
Vascular smooth muscle contraction
mcc04510
Focal adhesion
mcc04650
Natural killer cell mediated cytotoxicity
mcc04720
Long-term potentiation
mcc04722
Neurotrophin signaling pathway
mcc04726
Serotonergic synapse
mcc04730
Long-term depression
mcc04810
Regulation of actin cytoskeleton
mcc04910
Insulin signaling pathway
mcc04914
Progesterone-mediated oocyte maturation
mcc04928
Parathyroid hormone synthesis, secretion and action
mcc04934
Cushing syndrome
mcc05010
Alzheimer disease
mcc05022
Pathways of neurodegeneration - multiple diseases
mcc05034
Alcoholism
mcc05160
Hepatitis C
mcc05161
Hepatitis B
mcc05200
Pathways in cancer
mcc05205
Proteoglycans in cancer
mcc05208
Chemical carcinogenesis - reactive oxygen species
mcc05210
Colorectal cancer
mcc05211
Renal cell carcinoma
mcc05212
Pancreatic cancer
mcc05213
Endometrial cancer
mcc05214
Glioma
mcc05215
Prostate cancer
mcc05216
Thyroid cancer
mcc05218
Melanoma
mcc05219
Bladder cancer
mcc05220
Chronic myeloid leukemia
mcc05221
Acute myeloid leukemia
mcc05223
Non-small cell lung cancer
mcc05224
Breast cancer
mcc05225
Hepatocellular carcinoma
mcc05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
693554 (BRAF)
04012 ErbB signaling pathway
693554 (BRAF)
04015 Rap1 signaling pathway
693554 (BRAF)
04068 FoxO signaling pathway
693554 (BRAF)
04024 cAMP signaling pathway
693554 (BRAF)
04150 mTOR signaling pathway
693554 (BRAF)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
693554 (BRAF)
09142 Cell motility
04810 Regulation of actin cytoskeleton
693554 (BRAF)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
693554 (BRAF)
04062 Chemokine signaling pathway
693554 (BRAF)
09152 Endocrine system
04910 Insulin signaling pathway
693554 (BRAF)
04914 Progesterone-mediated oocyte maturation
693554 (BRAF)
04928 Parathyroid hormone synthesis, secretion and action
693554 (BRAF)
09153 Circulatory system
04270 Vascular smooth muscle contraction
693554 (BRAF)
09156 Nervous system
04726 Serotonergic synapse
693554 (BRAF)
04720 Long-term potentiation
693554 (BRAF)
04730 Long-term depression
693554 (BRAF)
04722 Neurotrophin signaling pathway
693554 (BRAF)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
693554 (BRAF)
05205 Proteoglycans in cancer
693554 (BRAF)
05208 Chemical carcinogenesis - reactive oxygen species
693554 (BRAF)
09162 Cancer: specific types
05210 Colorectal cancer
693554 (BRAF)
05212 Pancreatic cancer
693554 (BRAF)
05225 Hepatocellular carcinoma
693554 (BRAF)
05226 Gastric cancer
693554 (BRAF)
05214 Glioma
693554 (BRAF)
05216 Thyroid cancer
693554 (BRAF)
05221 Acute myeloid leukemia
693554 (BRAF)
05220 Chronic myeloid leukemia
693554 (BRAF)
05218 Melanoma
693554 (BRAF)
05211 Renal cell carcinoma
693554 (BRAF)
05219 Bladder cancer
693554 (BRAF)
05215 Prostate cancer
693554 (BRAF)
05213 Endometrial cancer
693554 (BRAF)
05224 Breast cancer
693554 (BRAF)
05223 Non-small cell lung cancer
693554 (BRAF)
09172 Infectious disease: viral
05161 Hepatitis B
693554 (BRAF)
05160 Hepatitis C
693554 (BRAF)
09164 Neurodegenerative disease
05010 Alzheimer disease
693554 (BRAF)
05022 Pathways of neurodegeneration - multiple diseases
693554 (BRAF)
09165 Substance dependence
05034 Alcoholism
693554 (BRAF)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
693554 (BRAF)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
693554 (BRAF)
01522 Endocrine resistance
693554 (BRAF)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mcc01001
]
693554 (BRAF)
Enzymes [BR:
mcc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
693554 (BRAF)
Protein kinases [BR:
mcc01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
693554 (BRAF)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
ABC1
C1_2
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
693554
NCBI-ProteinID:
XP_014990564
Ensembl:
ENSMMUG00000042793
UniProt:
A0A1D5Q9W4
LinkDB
All DBs
Position
3:complement(167129803..167331819)
Genome browser
AA seq
763 aa
AA seq
DB search
MAALSGGGGGGAEPGQALFNGDMEPEAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEAL
LDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLEYLGNGTDFSVSSSASMDTVTSSS
SSSLSVLPSSLSVFQNPTDVSRSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKA
LMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFT
LAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEE
ASLAETALTSGSSPSAPTSDSLGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQRDRSS
SAPNVHINTIEPVNIDDLIRDQGFRGDGGSTTGLSATPPASLPGSLTNVKALQKSPGPQR
ERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKM
LNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHII
ETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRW
SGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQ
IIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKI
HRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGEFAAFK
NT seq
2292 nt
NT seq
+upstream
nt +downstream
nt
atggcggcgctgagcggtggcggtggtggcggcgcggagccgggccaggctctgttcaac
ggggacatggagcccgaggccggcgccgcggcctcttcggctgcggaccctgccattccg
gaggaggtgtggaatatcaaacaaatgattaagttgacacaggaacatatagaggcccta
ttggacaaatttggtggggagcataatccaccatcaatatatctggaggcctatgaagaa
tacaccagcaagctagatgcactccaacaaagagaacaacagttattggaatatctgggg
aacggaactgatttttctgtttctagctctgcatcaatggacaccgttacatcttcttcc
tcttctagcctttcagtgctaccttcatctctttcagtttttcaaaatcccacagatgtg
tcacggagcaaccccaagtcaccacaaaaacctatcgttagagtcttcctacccaacaaa
cagaggacagtggtacctgcaaggtgtggagttacagtccgagacagtctaaagaaagca
ctgatgatgagaggtctaatcccagaatgctgtgctgtttacagaattcaggatggagag
aagaaaccaattggctgggacactgatatttcctggcttactggagaagaattgcatgtg
gaagtgttggagaatgttccacttacaacacacaactttgtacgaaaaacatttttcacc
ttagcattttgtgacttttgtcgaaagctgcttttccagggtttccgctgtcaaacatgt
ggttataaatttcaccagcgttgtagtacagaggttccactgatgtgtgttaattatgac
caacttgatttgctgtttgtctccaagttctttgaacaccacccaataccacaggaagag
gcctccttagcagagactgccctaacatctggatcatccccttccgcacccacctcagac
tctcttgggccccaaattctcaccagtccgtctccttcaaaatccattccaattccacag
cccttccgaccagcagatgaagatcatcgaaatcaatttgggcaacgagaccggtcctca
tcagctcccaatgtgcacataaacacaatagaacctgtcaatattgatgacttgattaga
gaccaaggatttcgtggtgatggaggatcaaccacaggtttgtctgccaccccccctgcc
tcattacctggctcactcactaacgtgaaagccttacagaaatctccaggacctcagcga
gaaaggaagtcatcttcatcctcagaagacaggaatcgaatgaaaacacttggtagacgg
gactcgagtgatgactgggagattcctgatgggcagattacagtgggacaaagaattgga
tctggttcatttggaacagtctacaagggaaagtggcatggtgatgtggcagtgaaaatg
ttgaatgtgacagcacctacacctcagcagttacaagccttcaaaaatgaagtaggagta
ctcaggaaaacacgacacgtgaatatcctactcttcatgggctattccacaaagccacaa
ctggctattgttacccagtggtgcgagggctccagcttgtatcaccatctccatatcatt
gagaccaaatttgagatgatcaaacttatagatattgcacgacagactgcacagggcatg
gattacttacacgccaagtcaatcatccacagagacctcaagagtaataatatatttctt
catgaagacctcacagtaaaaataggtgattttggtctagctacagtgaaatctcgatgg
agtgggtcccatcagtttgaacagttgtctggatccattttgtggatggcaccagaagtc
atcagaatgcaagataaaaatccatacagctttcagtcagatgtatatgcatttgggatt
gttctgtatgaattgatgactggacagttaccttattcaaatatcaataacagggaccag
ataatttttatggtgggacgaggatacctatctccagatctcagtaaggtacggagtaac
tgtccaaaagccatgaagagattaatggcagagtgcctcaaaaagaaaagagatgaaaga
ccactctttccccaaattctcgcctctattgagctgctggcccgctcattgccaaaaatt
caccgcagtgcatcagaaccctccttgaatcgggctggtttccaaacagaggattttagt
ctatatgcttgtgcttctccaaaaacacccatccaggcagggggatatggagaatttgca
gccttcaagtag
DBGET
integrated database retrieval system