Microtus fortis (reed vole): 126511730 Help Entry 126511730         CDS       T08493                                  Name (RefSeq) tyrosine-protein kinase JAK2   KO K04447   Janus kinase 2 [EC:2.7.10.2] Organism mfot  Microtus fortis (reed vole) Pathway mfot01521   EGFR tyrosine kinase inhibitor resistance mfot04062   Chemokine signaling pathway mfot04148   Efferocytosis mfot04151   PI3K-Akt signaling pathway mfot04217   Necroptosis mfot04550   Signaling pathways regulating pluripotency of stem cells mfot04630   JAK-STAT signaling pathway mfot04658   Th1 and Th2 cell differentiation mfot04659   Th17 cell differentiation mfot04725   Cholinergic synapse mfot04917   Prolactin signaling pathway mfot04920   Adipocytokine signaling pathway mfot04933   AGE-RAGE signaling pathway in diabetic complications mfot04935   Growth hormone synthesis, secretion and action mfot05140   Leishmaniasis mfot05145   Toxoplasmosis mfot05152   Tuberculosis mfot05161   Hepatitis B mfot05164   Influenza A mfot05167   Kaposi sarcoma-associated herpesvirus infection mfot05168   Herpes simplex virus 1 infection mfot05200   Pathways in cancer mfot05207   Chemical carcinogenesis - receptor activation mfot05235   PD-L1 expression and PD-1 checkpoint pathway in cancer mfot05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:mfot00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     126511730    04151 PI3K-Akt signaling pathway     126511730  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     126511730   09143 Cell growth and death    04217 Necroptosis     126511730   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     126511730  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     126511730    04659 Th17 cell differentiation     126511730    04062 Chemokine signaling pathway     126511730   09152 Endocrine system    04920 Adipocytokine signaling pathway     126511730    04917 Prolactin signaling pathway     126511730    04935 Growth hormone synthesis, secretion and action     126511730   09156 Nervous system    04725 Cholinergic synapse     126511730  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     126511730    05207 Chemical carcinogenesis - receptor activation     126511730    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     126511730   09172 Infectious disease: viral    05161 Hepatitis B     126511730    05164 Influenza A     126511730    05168 Herpes simplex virus 1 infection     126511730    05167 Kaposi sarcoma-associated herpesvirus infection     126511730   09171 Infectious disease: bacterial    05152 Tuberculosis     126511730   09174 Infectious disease: parasitic    05145 Toxoplasmosis     126511730    05140 Leishmaniasis     126511730   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     126511730   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     126511730   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     126511730  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:mfot01001]     126511730 Enzymes [BR:mfot01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      126511730 Protein kinases [BR:mfot01001]  Non-receptor tyrosine kinases   JAK family [OT]    126511730 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 FERM_F1 SH2_1 Jak1_Phl SH2 ABC1 FERM_C_FAK1 RIO1 Kinase-like Motif Other DBs NCBI-GeneID:  126511730 NCBI-ProteinID:  XP_050015068 LinkDB All DBs Position Unknown AA seq 1132 aa AA seqDB search MGMACLTMTEMEATSTSPVHQNGDIPGNANSVKQIDPVLQVYLYHSLGKAEGDYLKFPIG EYVAEEICVAASKACGITPVYHNMFALMSETERIWYPPNHVFHIDESTRHNILYRIRFYF PHWYCSGSNRTYRYGVSRGAEAPLLDDFVMSYLFAQWRHDFVHGWIKVPVTHETQEECLG MAVLDMMRIAKEKDQTPLAVYNSISYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQQF SQCKATARNLKLKYLINLETLQSAFYTEQFEVKESARGPSGEEIFATIIITGNGGIQWSR GRHKESETLAEQDLQLYCDFPDIIDVSIKQANQECSNESRIVTIHKQDGKILEIELSSLR EALSFVSLIDGYYRLTADAHHYLCKEVAPPSVLENLHSNCHGPISMDFAISKLKKAGNQT GLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLIMKNENREYNLSGTKKNFSNLKDLLNC YQMETVRSDSIIFQFTKCCPPKPKDKSNLLVFRTNGISDVQISPTLQRHNNVNQMVFHKI RNEDLVFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM MSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLGVAKQLAWA MHFLEEKSLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVP PECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDKHQLPAPKWTEL ANLINNCMDYEPDFRPAFRAVIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRD PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE ILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQI CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFW YAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPVEFMRMIGNDKQGQMIVFHLIE LLKNNGRLPRPEGCPDEIYVIMTECWNNSVNQRPSFRDLALRVDQIRDSLAV NT seq 3399 nt NT seq  +upstreamnt  +downstreamnt atgggaatggcttgccttacaatgacagagatggaggcaacctccacatctcctgtacat cagaatggtgatattcctggaaatgctaattctgtgaagcagatagatccagtccttcaa gtgtatctctaccattctcttgggaaagctgaaggagactatctgaagtttccaattgga gagtatgttgcagaagagatttgtgtggctgcttctaaagcttgtggtattacacctgtg tatcataatatgtttgctttaatgagtgaaacagaaagaatctggtatccacccaaccat gtcttccacatagatgagtcaaccaggcataatatactctacagaataagattttacttt cctcactggtattgcagtggcagcaatagaacctatagatacggagtatctcgtggggct gaagctcctcttcttgatgactttgtcatgtcttacctttttgctcagtggcggcatgat tttgtgcatgggtggataaaagtgcctgtgacccacgaaactcaagaagaatgtcttggg atggcagtgctagatatgatgagaatagccaaagaaaaggaccaaactccactggctgtc tataactctatcagctacaaaacattcttaccaaagtgtgttcgagcaaagattcaagac tatcatattttaacccggaagcgaataaggtacagatttcgcagattcattcagcagttc agtcaatgcaaagccactgccagaaacctgaaacttaagtatcttataaacttggaaacc ctacagtctgccttctacacagagcaatttgaagtaaaagaatctgcaagaggtccttca ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga gggagacataaagaaagtgagacactggcagaacaggatttacagttatattgtgatttt cctgatattattgatgtcagtattaagcaagcaaaccaggaatgctcaaatgaaagtaga attgtaactatccataagcaagatggtaaaattttggaaatagagcttagctcgttaaga gaagccctgtcatttgtgtccttgattgatggctattaccgcctcactgcggacgcacac cattacctctgtaaggaggtggcccctccgtctgtgctggagaacttgcacagcaactgc catggccccatctcaatggattttgccattagtaaactaaagaaggcagggaaccagacg ggactgtatgtacttcggtgtagccctaaggactttaacaagtactttctgacctttgct gttgagcgagaaaatgttattgaatataaacactgtttgattatgaagaatgaaaataga gagtacaatctcagtgggactaagaagaacttcagtaatcttaaggaccttttgaattgc taccagatggaaactgtgcgctcagacagtatcatcttccagtttactaaatgctgtccc cctaagcccaaagacaaatcaaaccttcttgtcttcagaaccaatggtatttctgatgtt cagatctcaccaacattacagaggcataataatgtgaaccagatggtgtttcacaaaatc agaaatgaagacttggtatttaatgaaagtcttggccaaggtacttttacaaaaattttt aaaggtgtaagaagagaagttggagactatggtcaactgcatgaaacagaagttcttttg aaagttctggataaagcacataggaattattcagagtctttctttgaagcagcaagcatg atgagccagctttctcacaagcacttggttttgaattatggagtatgtgtctgtggagag gagaacattctggttcaagagtttgtaaaatttggatcactggatacatacctgaaaaaa aacaaaaattccataaatatattatggaaacttggagtggctaaacagttggcatgggcc atgcattttctagaagaaaaatcccttattcatgggaatgtgtgtgccaaaaatatcctg ctgatcagagaagaagacaggaaaacagggaatccacctttcatcaaacttagtgaccct ggcattagcattacagttctaccaaaggacattcttcaggagagaataccatgggttcca cctgaatgcattgaaaatcctaaaaatctaaatctggcgacagacaagtggagttttggt actactctgtgggaaatctgcagcggaggagacaagcccctgagtgctctggactcgcaa aggaagttacagttttatgaagataagcatcagcttcctgcacctaagtggacagaatta gcgaatcttataaacaattgcatggattatgagccagatttcaggcctgccttcagagct gtcatccgtgatcttaatagcctgtttactccagattatgaactactaacagaaaatgac atgctaccaaatatgagaataggtgccttaggattttctggtgcttttgaagacagagac cctacacaatttgaagagagacacttgaaatttctacagcaacttggcaagggtaatttt gggagtgtggagatgtgccgctacgatcctctacaggacaacactggggaggtggtggct gttaaaaaactccagcacagcactgaagagcatctcagagacttcgaaagggagattgaa atcctgaaatccttgcagcatgacaacattgtaaaatacaaaggagtgtgctacagtgct ggtcggcgcaacctaagattaattatggaatatttgccatatggaagtttacgagactat ctccaaaagcataaagaacgaatagatcacaaaaaacttctgcagtacacatctcagata tgcaagggcatggaatatcttggcacaaaaagatatatccatagggatttggcaacaaga aatatattggtggaaaatgagaacagagttaaaataggagattttggattaaccaaagtc ttgccacaggacaaagaatactacaaagtaaaagaaccaggcgaaagtcccatattctgg tatgctccagaatccctgacagagagcaagttttctgtggcctcggatgtatggagcttt ggcgtggttctgtatgagcttttcacatatattgagaagagtaaaagtcctccagtggaa tttatgcgaatgattggcaatgataaacaaggacagatgattgtgttccatttgatagaa cttctgaagaacaatggaagactaccaagaccagaagggtgcccagatgagatttatgtg atcatgacagagtgctggaacaacagtgtaaatcagcgtccctctttcagggacctagca cttcgggtggatcagatccgggacagtctggctgtgtga

DBGET integrated database retrieval system