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Myotis myotis (greater mouse-eared bat): 118667512
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Entry
118667512 CDS
T07220
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2 isoform X1
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
mmyo
Myotis myotis (greater mouse-eared bat)
Pathway
mmyo01521
EGFR tyrosine kinase inhibitor resistance
mmyo04062
Chemokine signaling pathway
mmyo04148
Efferocytosis
mmyo04151
PI3K-Akt signaling pathway
mmyo04217
Necroptosis
mmyo04550
Signaling pathways regulating pluripotency of stem cells
mmyo04630
JAK-STAT signaling pathway
mmyo04658
Th1 and Th2 cell differentiation
mmyo04659
Th17 cell differentiation
mmyo04725
Cholinergic synapse
mmyo04917
Prolactin signaling pathway
mmyo04920
Adipocytokine signaling pathway
mmyo04933
AGE-RAGE signaling pathway in diabetic complications
mmyo04935
Growth hormone synthesis, secretion and action
mmyo05140
Leishmaniasis
mmyo05145
Toxoplasmosis
mmyo05152
Tuberculosis
mmyo05161
Hepatitis B
mmyo05164
Influenza A
mmyo05167
Kaposi sarcoma-associated herpesvirus infection
mmyo05168
Herpes simplex virus 1 infection
mmyo05200
Pathways in cancer
mmyo05207
Chemical carcinogenesis - receptor activation
mmyo05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
mmyo05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mmyo00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
118667512 (JAK2)
04151 PI3K-Akt signaling pathway
118667512 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
118667512 (JAK2)
09143 Cell growth and death
04217 Necroptosis
118667512 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
118667512 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
118667512 (JAK2)
04659 Th17 cell differentiation
118667512 (JAK2)
04062 Chemokine signaling pathway
118667512 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
118667512 (JAK2)
04917 Prolactin signaling pathway
118667512 (JAK2)
04935 Growth hormone synthesis, secretion and action
118667512 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
118667512 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
118667512 (JAK2)
05207 Chemical carcinogenesis - receptor activation
118667512 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
118667512 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
118667512 (JAK2)
05164 Influenza A
118667512 (JAK2)
05168 Herpes simplex virus 1 infection
118667512 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
118667512 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
118667512 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
118667512 (JAK2)
05140 Leishmaniasis
118667512 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
118667512 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
118667512 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
118667512 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmyo01001
]
118667512 (JAK2)
Enzymes [BR:
mmyo01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
118667512 (JAK2)
Protein kinases [BR:
mmyo01001
]
Non-receptor tyrosine kinases
JAK family [OT]
118667512 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
Kdo
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
118667512
NCBI-ProteinID:
XP_036186939
LinkDB
All DBs
Position
Unknown
AA seq
1142 aa
AA seq
DB search
MEMACLTMTEMEGTCTPPMHQNGDIPGITDSVKQTDPVLQVYLYHSLGKTEGDYLKFSTG
EYVAEEICVAASKACGITPVYHSMFALMSETERIWYPPNYVFHIDESTRHNVLYRIRFYF
PYWYCSGSNRTYRHGISRGAEAPLLDDFVMSYLFAQWRHDFLHGWIKVPVTHETQEECLG
MAVLDMMRIAKENDQTPLDVYSSISYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIEQF
SHCKATAKNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSR
GKHKESETLTEQDLQLYCDFPDIIDVSIKQASQEGSNESRIVTIHKQDGKNLEIELSSLK
EALSFVSLIDGYYRLTADAHHYLCKEVASPVVLENIQSNCHGPISMDFAISKLKKAGNQT
GLYVLRCSPKEFNKYFLTFAVERDNVIEYKHCLITKNENGEYNLSGTKKNFNNLKDLLNC
YQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNSVSDVPTSPTLQRHNNVNQMVFHKI
RNEDLVFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM
MSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLEVAKQLAWA
MHFLEEKNLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISVTVLPKDILQERIPWVP
PECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTEL
ANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYGVLSFISADYELLTENDMLPNMRIGAL
GFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEE
HLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDH
KKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKV
KEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQ
GQMIVFHLIELLKNNGRLPRPDGCPDEIYVIMTECWNNNVNQRPSFRNLALRVDQIRDNI
AG
NT seq
3429 nt
NT seq
+upstream
nt +downstream
nt
atggaaatggcttgcctcacaatgacagaaatggaaggaacatgcacacctcctatgcat
cagaatggagatattcctggaattactgattctgtgaagcaaacagatccagtccttcag
gtgtatctttatcattcccttgggaaaactgagggagattacctgaagttttcaactggg
gaatatgttgcagaagaaatttgtgttgctgcttctaaagcctgtggaatcacacctgtg
tatcatagtatgtttgctttaatgagtgaaacagaaaggatctggtatccgcccaactat
gtcttccatatagatgagtcaaccaggcacaatgtactctacagaataagattttacttt
ccttactggtattgtagcggcagcaacagaacttatcggcatggaatatctcgaggtgct
gaagctcctcttcttgatgactttgttatgtcttacctttttgctcagtggcggcatgat
tttttgcatggatggataaaagtacctgtgactcatgaaacacaggaagaatgtcttggg
atggcagtgttagatatgatgagaatagccaaagaaaatgatcaaaccccactcgacgtc
tatagctctatcagctataagacattcttaccaaaatgtattcgagcaaagatccaagac
tatcatattttgacaagaaagcgaataaggtaccgatttcgcagatttattgagcaattc
agccattgcaaagccactgccaaaaacttgaaacttaagtatcttataaatctggaaact
cttcagtctgccttctacacagagcaatttgaagtaaaagaacctggaagaggtccttca
ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga
gggaaacataaagaaagtgaaacactgacagaacaggatttacagttatattgtgacttt
cccgatattattgatgtcagtattaagcaggcaagccaagaaggctcaaatgaaagcaga
attgtaactatccataagcaagatggtaaaaacctggaaattgaacttagttcattaaag
gaggctttgtcttttgtgtcattaattgatggatattatagattaactgcagatgcacat
cattacctctgtaaagaagtagcatctccagtggtgcttgaaaatatacaaagcaattgt
catggcccaatttcaatggattttgccataagtaaactgaagaaagcaggtaatcagact
ggactttatgtacttcgatgcagtcctaaggagtttaataaatattttttgacttttgct
gtcgagcgtgataatgtcattgaatataagcactgtttgattacaaaaaatgagaatgga
gaatacaacctcagtggaactaagaagaacttcaataatcttaaagatcttttgaattgc
taccagatggaaactgttcgctcagacaatataattttccagtttacaaaatgctgtcct
ccaaagccaaaagataaatcaaaccttctcgtctttagaacaaatagtgtttctgatgta
ccaacctcaccaacattacagagacataataatgtgaaccaaatggtgtttcacaaaatc
agaaatgaagatttagtatttaatgaaagtcttggccaaggcacttttacaaaaattttt
aaaggtgtaagaagagaagtaggagattatggtcaactgcatgaaacagaagttctttta
aaagttttggataaagcacatagaaactattcagagtctttctttgaagcagcaagcatg
atgagccagctttctcacaagcatctggttttaaattatggagtatgtgtctgtggagag
gagaatattctggttcaggagtttgtgaaatttggatcactagatacatatttgaaaaag
aataaaaattctataaatatattatggaaacttgaagtggctaaacagttggcatgggcc
atgcattttctagaagaaaaaaaccttattcatgggaatgtatgtgccaaaaacattcta
cttatcagagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgatcct
ggcattagtgttacagttttgccaaaggacattcttcaggagagaataccatgggtacca
cctgaatgtattgaaaatcctaaaaacttaaacttggcaacagacaaatggagttttggt
accactttgtgggaaatctgcagtggaggagacaagcctctgagtgctttggattctcaa
agaaagctacagttttatgaagatagacaccagcttcctgcaccaaagtggacagaatta
gcaaatcttattaataattgtatggattatgaaccagattttagaccttctttcagagcc
atcatacgagatcttaatagtttgtttactccagattatggtgtattatcctttatttct
gcagattatgaattgttaacagagaatgacatgttaccaaatatgaggataggtgcccta
gggttttctggagcttttgaagaccgagaccctactcagtttgaagagagacacttgaaa
tttctgcagcaacttggcaagggtaactttgggagtgttgagatgtgccggtatgaccct
ctacaagacaacactggggaggtggtggctgtgaaaaagctccagcacagtactgaagag
cacctcagagactttgaaagggaaattgaaatccttaaatccctgcagcatgacaacatt
gtaaagtacaagggagtgtgctacagtgctggccggcgtaatctaagattaattatggaa
tatttaccatatggaagtttacgggactatctccaaaagcataaagaacgaatagatcat
aagaaacttctgcaatatacatctcagatatgcaagggtatggaatatcttggtacgaaa
aggtatatccacagggatctggcaacaaggaatatattggtagagaatgaaaacagagtt
aaaattggagattttgggttaaccaaagtcttgccacaagacaaagaatactacaaagtg
aaagaacctggtgaaagccctatattctggtatgctccagaatcactgacagagagcaag
ttttccgtggcctcagatgtgtggagctttggagtggttctatatgaacttttcacctat
attgagaagagtaaaagtccaccagcggaattcatgcgtatgattggcaacgacaaacaa
ggacagatgattgtgtttcatttgatagaacttttgaagaataatggaagattaccaaga
ccagatggatgcccagatgagatctatgtgatcatgacagaatgctggaataataatgta
aatcaacgtccgtctttcagaaacctagctcttcgagttgatcaaataagggacaacata
gctggatga
DBGET
integrated database retrieval system
