Svoboda
|
Graniru
|
BBC Russia
|
Golosameriki
|
Facebook
Miniopterus natalensis (Natal long-fingered bat): 107538122
Help
Entry
107538122 CDS
T05883
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
mna
Miniopterus natalensis (Natal long-fingered bat)
Pathway
mna01521
EGFR tyrosine kinase inhibitor resistance
mna04062
Chemokine signaling pathway
mna04148
Efferocytosis
mna04151
PI3K-Akt signaling pathway
mna04217
Necroptosis
mna04550
Signaling pathways regulating pluripotency of stem cells
mna04630
JAK-STAT signaling pathway
mna04658
Th1 and Th2 cell differentiation
mna04659
Th17 cell differentiation
mna04725
Cholinergic synapse
mna04917
Prolactin signaling pathway
mna04920
Adipocytokine signaling pathway
mna04933
AGE-RAGE signaling pathway in diabetic complications
mna04935
Growth hormone synthesis, secretion and action
mna05140
Leishmaniasis
mna05145
Toxoplasmosis
mna05152
Tuberculosis
mna05161
Hepatitis B
mna05164
Influenza A
mna05167
Kaposi sarcoma-associated herpesvirus infection
mna05168
Herpes simplex virus 1 infection
mna05200
Pathways in cancer
mna05207
Chemical carcinogenesis - receptor activation
mna05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
mna05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mna00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
107538122 (JAK2)
04151 PI3K-Akt signaling pathway
107538122 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
107538122 (JAK2)
09143 Cell growth and death
04217 Necroptosis
107538122 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
107538122 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
107538122 (JAK2)
04659 Th17 cell differentiation
107538122 (JAK2)
04062 Chemokine signaling pathway
107538122 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
107538122 (JAK2)
04917 Prolactin signaling pathway
107538122 (JAK2)
04935 Growth hormone synthesis, secretion and action
107538122 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
107538122 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
107538122 (JAK2)
05207 Chemical carcinogenesis - receptor activation
107538122 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
107538122 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
107538122 (JAK2)
05164 Influenza A
107538122 (JAK2)
05168 Herpes simplex virus 1 infection
107538122 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
107538122 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
107538122 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
107538122 (JAK2)
05140 Leishmaniasis
107538122 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
107538122 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
107538122 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
107538122 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mna01001
]
107538122 (JAK2)
Enzymes [BR:
mna01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
107538122 (JAK2)
Protein kinases [BR:
mna01001
]
Non-receptor tyrosine kinases
JAK family [OT]
107538122 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
Kdo
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
107538122
NCBI-ProteinID:
XP_016069747
LinkDB
All DBs
Position
Unknown
AA seq
1132 aa
AA seq
DB search
MEMACLTMTEMEGTHTSPVHQNGDIPGMADSVKQIDSVLQVYLYHSLGKTEGDYLKFPTG
EYVAEEICVAASKACGITPLYHNMFALMSETERIWYPPNHVFHIDESTRHNVFYRIRFYF
PYWYCSGSNRTYRHGISRGAEAPLLDDFVMSYLFAQWRHDFLHGWIKVPVTHETQEECLG
MAVLDMMRIAKENDQTPLDIYSSISYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIEQF
SHCKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSR
GKHKECETLTEQDLQLYCDFPDIIDVSIKQANQEGSNESRIVTIHKQDGKNLEIELSSLK
EALSFVSLIDGYYRLTADAHHYLCKEVASPVVLENIQSNCHGPISMDFAISKLKKAGNQT
GLYVLRCSPKEFNKYFLTFAVERENVIEYKHCLITKNENGEYNLTGTKKNFSNLKDLLNC
YQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNSVSDVPTSPTLQRHNNVNQMVFHKI
RNEDLVFNESLGQGTFTKIFKGIRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM
MSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLEVAKQLAWA
MHFLEEKNLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISVTVLPKDILQERIPWVP
PECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTEL
ANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRD
PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE
ILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQI
CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFW
YAPESLTESRFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIE
LLKNNGRLPRPDGCPDEIYVIMTECWNNNVNQRPSFRHLALRVDQIRDNMAG
NT seq
3399 nt
NT seq
+upstream
nt +downstream
nt
atggaaatggcttgccttacaatgacagaaatggaaggaacacacacatctcctgtacat
cagaatggtgatatccctggaatggctgattctgtgaaacaaatagattcagtcctacag
gtgtatctttatcattcccttgggaaaactgagggagattacctgaagtttccaactggg
gagtatgttgcagaagaaatttgtgttgctgcttctaaagcctgtggaatcacacctttg
tatcataatatgtttgctttaatgagtgaaacagaaaggatctggtatccgcccaaccac
gtcttccacatagatgaatcaaccaggcacaatgtattctacagaataaggttttacttt
ccttactggtattgcagcggcagcaacagaacgtatcggcatggaatatctcgaggtgct
gaagctccccttcttgacgactttgtcatgtcttacctttttgctcagtggcgtcatgat
tttttgcatggatggataaaagtacctgtgacccatgaaacacaggaagaatgtcttggg
atggcagtgttagatatgatgagaatagccaaagaaaatgaccaaaccccactcgacatc
tatagctctatcagctacaagacattcttaccaaaatgtattcgagcaaagatccaagac
tatcatattttgacaagaaagcgaataaggtacagatttcgcagatttattgagcagttc
agccattgcaaagccactgccagaaatttgaaacttaagtatcttataaatctggaaact
cttcagtctgccttctacacagagcaatttgaagtaaaagaacctggaagaggtccttca
ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga
gggaaacataaagaatgtgagacactgacagaacaggatttacagttatattgtgatttt
cctgatattattgatgtcagtattaagcaggcaaatcaagaaggctcaaatgaaagcaga
attgtaactatccataagcaagatggtaaaaatctggaaattgaacttagctcattaaag
gaagctttgtcttttgtgtcattaattgatggatattatagattaactgcagatgcacat
cattacctctgtaaagaagtagcatctccagtggtgcttgaaaatatacaaagcaactgt
catggcccaatttcaatggattttgccataagtaaactgaagaaagcaggtaatcagact
ggactatatgtacttcgatgcagtcctaaggagtttaataaatattttttgacttttgct
gttgagcgagaaaatgtcattgaatataagcactgtttgattacaaaaaatgagaatgga
gaatacaacctcactgggactaagaagaacttcagtaatcttaaagatcttttgaattgc
taccagatggaaactgttcgctcagacaatataattttccagtttacaaaatgctgtccc
ccaaagccaaaagataaatcaaaccttctagtcttcagaacgaatagtgtttctgatgta
ccaacctcaccaacactacagaggcataataatgtgaaccaaatggtgtttcacaaaatc
agaaatgaagatttggtatttaatgaaagccttggccaaggcacttttacaaaaattttc
aaaggtataagaagagaagtaggagactatggtcaactacatgaaacagaagttctttta
aaagttctggataaagcacatagaaactattcagagtctttctttgaagcagcaagcatg
atgagccagctttctcacaagcacctggttttaaattatggagtatgtgtctgtggagag
gagaatattctggttcaggagtttgtgaaatttggatcactagatacatatttgaaaaag
aataaaaattctataaatatattatggaaacttgaagtggctaaacaattggcatgggcc
atgcattttctagaagaaaaaaaccttattcatgggaatgtatgtgccaaaaatattcta
cttatcagagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgatcct
ggcattagtgttacagttttgccaaaggacattcttcaggagagaataccatgggtaccg
cctgaatgcattgaaaatcctaaaaatttaaacttggcaacagacaaatggagttttggt
accactttgtgggaaatctgcagcggaggagataagcctctgagtgctttggattctcaa
agaaagctacagttttatgaagataggcaccagcttcctgcaccaaagtggacagaatta
gccaatcttattaataattgtatggattatgagccagattttagaccttctttcagagcc
atcatacgagatcttaatagtttgtttactccagattatgaactattaacagagaatgac
atgttaccaaatatgaggataggtgccctagggttttctggggcttttgaagaccgagac
cctactcagtttgaagagagacacttgaaatttctgcagcaacttggcaagggtaatttt
gggagtgtcgagatgtgccggtatgatcctctacaagacaacactggggaggtggtggct
gtgaaaaaactccagcacagtactgaagagcacctcagagactttgaaagggaaatcgaa
atccttaaatccctgcagcatgacaacattgtaaagtacaagggagtgtgctatagtgct
ggccggcgtaatctaagattaattatggaatatttaccatatggaagtttacgagactat
ctccaaaagcataaagaacgaatagatcataaaaaacttctgcagtatacatctcaaata
tgcaagggtatggagtatcttggtacaaaaaggtatatccacagggacctggcaacaagg
aatatattggtggagaatgaaaacagagttaaaattggagattttgggttaaccaaagtc
ttgccacaagacaaagaatactacaaagtgaaagaacctggtgaaagtcccatattctgg
tatgctccagaatcactgacagagagcaggttttctgtggcctcagatgtttggagcttt
ggagtggttctgtatgaacttttcacctatattgagaagagtaaaagtccaccagcggaa
ttcatgcgtatgattggcaacgacaaacaagggcagatgattgtgttccacttgatagag
ctcctgaagaacaacgggcggctacccagaccagatggctgcccggacgagatttatgtg
atcatgacagaatgttggaataataatgtaaatcagcgcccctctttcagacacctagct
cttcgagttgatcaaataagggacaacatggctggatga
DBGET
integrated database retrieval system
