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Mustela putorius furo (domestic ferret): 101671881
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Entry
101671881 CDS
T07239
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
mpuf
Mustela putorius furo (domestic ferret)
Pathway
mpuf01521
EGFR tyrosine kinase inhibitor resistance
mpuf04062
Chemokine signaling pathway
mpuf04148
Efferocytosis
mpuf04151
PI3K-Akt signaling pathway
mpuf04217
Necroptosis
mpuf04550
Signaling pathways regulating pluripotency of stem cells
mpuf04630
JAK-STAT signaling pathway
mpuf04658
Th1 and Th2 cell differentiation
mpuf04659
Th17 cell differentiation
mpuf04725
Cholinergic synapse
mpuf04917
Prolactin signaling pathway
mpuf04920
Adipocytokine signaling pathway
mpuf04933
AGE-RAGE signaling pathway in diabetic complications
mpuf04935
Growth hormone synthesis, secretion and action
mpuf05140
Leishmaniasis
mpuf05145
Toxoplasmosis
mpuf05152
Tuberculosis
mpuf05161
Hepatitis B
mpuf05164
Influenza A
mpuf05167
Kaposi sarcoma-associated herpesvirus infection
mpuf05168
Herpes simplex virus 1 infection
mpuf05200
Pathways in cancer
mpuf05207
Chemical carcinogenesis - receptor activation
mpuf05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
mpuf05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mpuf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
101671881 (JAK2)
04151 PI3K-Akt signaling pathway
101671881 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
101671881 (JAK2)
09143 Cell growth and death
04217 Necroptosis
101671881 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
101671881 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
101671881 (JAK2)
04659 Th17 cell differentiation
101671881 (JAK2)
04062 Chemokine signaling pathway
101671881 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
101671881 (JAK2)
04917 Prolactin signaling pathway
101671881 (JAK2)
04935 Growth hormone synthesis, secretion and action
101671881 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
101671881 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101671881 (JAK2)
05207 Chemical carcinogenesis - receptor activation
101671881 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101671881 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
101671881 (JAK2)
05164 Influenza A
101671881 (JAK2)
05168 Herpes simplex virus 1 infection
101671881 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
101671881 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
101671881 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
101671881 (JAK2)
05140 Leishmaniasis
101671881 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101671881 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
101671881 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101671881 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mpuf01001
]
101671881 (JAK2)
Enzymes [BR:
mpuf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
101671881 (JAK2)
Protein kinases [BR:
mpuf01001
]
Non-receptor tyrosine kinases
JAK family [OT]
101671881 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
101671881
NCBI-ProteinID:
XP_004766235
Ensembl:
ENSMPUG00000004974
UniProt:
M3Y0T4
LinkDB
All DBs
Position
Unknown
AA seq
1130 aa
AA seq
DB search
MACLTMTEMEGTSVSPVHQNGDVPGNANPVKQIDPLLQVYLYHSLEKAEGEYLKFPTGEY
AAEEICVAASKACGITPVYHSMFALMSETERIWYPPNHVFHIDESTRHNVLYRIRFYFPY
WYCNGSNRTYRYGISRGAETPLLDDFVMAYLFAQWRHDFLHGWIKIPVTHETQEECLGMA
VLDMMRLAKEKDQTPLDIYSSISYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIEQFSH
CKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSRGK
HKESETLTEQDLQLYCDFPDIIDVTIKQASQEGSNESRIVTIHKQDGKNLEIELSSLKEA
LSFVSLIDGYYRLTADAHHYLCKEVAPPMVLENIQSNCHGPILMDFAISKLKKAGNQTGL
YVLRCSPKDFNKYFLTFAVERENAIEYKHCLITKNENGEYNLSGTKKNFSNLKDLLNCYQ
METVRSDSIIFQFTKCCPPKLKDKSNLLVFRTSGISDVPTSPTLQRHNNVNQMVFHKIRN
EDLMFNESLGQGTFTKIFKGIRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMS
QLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLEVAKQLAWAMH
FLEEKALVHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPE
CTENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTELAN
LINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDPT
QFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEIL
KSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQICK
GMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYA
PESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELL
KNNGRLPRPDGCPDEIYLIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG
NT seq
3393 nt
NT seq
+upstream
nt +downstream
nt
atggcttgccttacaatgacagaaatggaaggaacgtccgtatcccctgtacatcagaac
ggtgatgttcctggaaatgctaatccggtgaagcaaatagatccactcctacaggtgtat
ctttaccattctcttgagaaagctgaaggagagtatctgaagtttccaactggggagtat
gctgcagaagaaatctgtgttgctgcttctaaagcttgtggaatcacacctgtgtatcat
agtatgtttgctttaatgagtgaaacagaaaggatttggtatccgcccaaccatgtcttc
catatagatgaatcaaccaggcacaatgtactctacagaataagattttactttccttac
tggtattgtaacggcagcaacagaacctatcggtatgggatatctcgaggtgctgaaact
cctcttcttgacgactttgtcatggcctacctttttgctcagtggcggcatgatttttta
catggatggataaaaatacctgtgactcatgaaacacaagaagaatgtcttggaatggct
gtgttagatatgatgagactagccaaagagaaagatcagaccccattggacatctatagc
tctatcagctacaagacattcttaccaaaatgtgttcgagcaaagatccaagactatcat
attttgacaaggaaacgaataaggtacagatttcgcagatttattgagcagttcagccat
tgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaactcttcag
tcagccttctacacagagcaatttgaagtaaaagaacctggaagaggtccttcaggtgag
gagatttttgcaaccattataataactggaaacggtggaattcagtggtcaagagggaaa
cataaagaaagtgagacactgacagaacaggatttacagttatattgtgacttccctgat
attattgatgttactattaagcaagcaagccaagaaggctcaaatgaaagtagaattgta
actatacataagcaagatggtaaaaatctggaaattgaacttagctcattaaaagaagct
ttgtcctttgtgtcattaattgatggctattatagattaactgcagatgcacatcattac
ctctgtaaagaagtagcacctccaatggtccttgaaaatatacaaagcaactgtcatggc
ccaattttaatggattttgccatcagtaaactgaagaaagcaggtaatcagactggactc
tacgtacttcgatgcagtcctaaggattttaataagtattttctgacttttgctgttgag
cgagaaaatgccattgaatataagcactgtttgattacaaagaatgaaaatggagaatac
aacctcagtgggaccaagaagaacttcagtaaccttaaagatcttttgaattgctaccag
atggaaactgttcgctcagacagtataattttccagtttactaaatgttgtcccccaaag
ttgaaagataaatcaaaccttctagtcttcagaaccagtggcatttctgatgttcccaca
tcaccaacattacagaggcacaataatgtgaaccaaatggtgtttcacaaaatcagaaat
gaagatttgatgtttaatgaaagccttggccaaggcacttttacaaaaatttttaaaggt
ataaggagagaagtaggagattatggtcaactacatgaaacagaagttcttttaaaagtt
ctggataaagctcacagaaactattccgagtctttctttgaagcagcaagcatgatgagc
cagctttctcacaagcatctagttttaaattatggagtgtgtgtctgtggggaggagaat
attctggttcaagagtttgtaaaatttggatcattagatacatatctgaaaaagaataaa
aattctataaatatattatggaaacttgaagtggctaaacagttggcatgggccatgcat
tttctagaagaaaaagcacttgttcatgggaatgtgtgtgccaaaaacattctgcttatc
agagaagaagacaggaagacaggaaaccctcctttcatcaaactcagtgaccctggcatt
agcattacagttttgccaaaggacattcttcaggagagaataccatgggtaccacctgaa
tgcactgaaaatcctaaaaatctaaatttggcgacagacaaatggagttttggtaccact
ttgtgggaaatctgcagtggaggagataaacctctgagtgctttggattctcaaagaaag
ctacagttttacgaagataggcaccagcttcctgcaccaaagtggacagaattagcaaat
cttattaataattgtatggattatgaaccagatttcagaccttctttcagagccatcata
cgagatcttaatagtttgtttactccagattatgaactactaacagaaaatgacatgtta
ccaaatatgagaataggtgccctggggttttctggtgcttttgaagaccgagaccctaca
caatttgaagagagacacttgaaatttctacagcaacttggcaagggtaattttggcagc
gtggagatgtgccggtatgaccccctgcaggacaacactggggaggtggtggctgtgaag
aagctccagcacagtactgaggagcacctgagagactttgagagggagattgaaatcctg
aaatccctgcagcatgacaacattgtgaagtacaagggagtgtgctacagtgctggtcgg
cgtaatctaagattaattatggaatatttaccatatggaagtttacgagactatctccaa
aaacataaagaacggatagatcataaaaaacttctgcagtatacatctcagatatgcaag
ggcatggagtatcttggtacaaaaagatatatccacagggatctggcaacaaggaatata
ttggtggaaaatgaaaacagggtaaaaattggagattttgggttaaccaaagtcttgcca
caagacaaagaatactacaaagtgaaagaacctggtgaaagtcccatattctggtatgct
ccagaatcactgacagagagcaagttttctgtggcttcagatgtttggagctttggagtg
gttctctatgaacttttcacatatattgagaagagtaaaagtcccccagcggaatttatg
cgcatgattggcaatgacaaacaaggacagatgattgtgtttcatttgatagaactcttg
aagaataatggaagattaccaagaccagatggatgcccagatgagatttatttgatcatg
acagaatgctggaacaataatgtcaatcaacgcccctcttttagagacctagctcttcga
gttgatcaaataagggacaacatggctggatga
DBGET
integrated database retrieval system