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Nannospalax galili (Upper Galilee mountains blind mole rat): 103740979
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Entry
103740979 CDS
T03372
Symbol
Jak2
Name
(RefSeq) Janus kinase 2
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
ngi
Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi01521
EGFR tyrosine kinase inhibitor resistance
ngi04062
Chemokine signaling pathway
ngi04148
Efferocytosis
ngi04151
PI3K-Akt signaling pathway
ngi04217
Necroptosis
ngi04550
Signaling pathways regulating pluripotency of stem cells
ngi04630
JAK-STAT signaling pathway
ngi04658
Th1 and Th2 cell differentiation
ngi04659
Th17 cell differentiation
ngi04725
Cholinergic synapse
ngi04917
Prolactin signaling pathway
ngi04920
Adipocytokine signaling pathway
ngi04933
AGE-RAGE signaling pathway in diabetic complications
ngi04935
Growth hormone synthesis, secretion and action
ngi05140
Leishmaniasis
ngi05145
Toxoplasmosis
ngi05152
Tuberculosis
ngi05161
Hepatitis B
ngi05164
Influenza A
ngi05167
Kaposi sarcoma-associated herpesvirus infection
ngi05168
Herpes simplex virus 1 infection
ngi05200
Pathways in cancer
ngi05207
Chemical carcinogenesis - receptor activation
ngi05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
ngi05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ngi00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
103740979 (Jak2)
04151 PI3K-Akt signaling pathway
103740979 (Jak2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
103740979 (Jak2)
09143 Cell growth and death
04217 Necroptosis
103740979 (Jak2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
103740979 (Jak2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
103740979 (Jak2)
04659 Th17 cell differentiation
103740979 (Jak2)
04062 Chemokine signaling pathway
103740979 (Jak2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
103740979 (Jak2)
04917 Prolactin signaling pathway
103740979 (Jak2)
04935 Growth hormone synthesis, secretion and action
103740979 (Jak2)
09156 Nervous system
04725 Cholinergic synapse
103740979 (Jak2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103740979 (Jak2)
05207 Chemical carcinogenesis - receptor activation
103740979 (Jak2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
103740979 (Jak2)
09172 Infectious disease: viral
05161 Hepatitis B
103740979 (Jak2)
05164 Influenza A
103740979 (Jak2)
05168 Herpes simplex virus 1 infection
103740979 (Jak2)
05167 Kaposi sarcoma-associated herpesvirus infection
103740979 (Jak2)
09171 Infectious disease: bacterial
05152 Tuberculosis
103740979 (Jak2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
103740979 (Jak2)
05140 Leishmaniasis
103740979 (Jak2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
103740979 (Jak2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
103740979 (Jak2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103740979 (Jak2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ngi01001
]
103740979 (Jak2)
Enzymes [BR:
ngi01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
103740979 (Jak2)
Protein kinases [BR:
ngi01001
]
Non-receptor tyrosine kinases
JAK family [OT]
103740979 (Jak2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
103740979
NCBI-ProteinID:
XP_008839879
UniProt:
A0A8C6Q9Y1
LinkDB
All DBs
Position
Un
AA seq
1132 aa
AA seq
DB search
MGMACLTMTEMEATSTPPVHQNGDIPGNASSVKQVDPVLQVYLYHSLGKAEGVYLKFPTG
EYVAEEICVAASKACGITPVYHNMFALMSEAERIWYPPNHVFHIDESTSHNILYRIRFYF
PHWYCSGSNRTYRYGISRGAEAPLLDDFVMSYLFAQWRHDFVHGWIKVPVTHETQEECLG
MAVLDMMRIAKEKDQTPLAIYNSISYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQQF
SQCKATARNLKLKYLINLETLQSAFYTEQFEVKESARGPSGEEIFATIIITGNGGIQWSR
GKHKESETLTEQDLQLYCDFPDIIDVSIKQANQECSNESRIVTIHKQDGKILEIELSSLR
EALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQT
GLYVLRCSPKDFDKYFLTFAVERDNIIEYKHCLITKNENREYNLSGTKRNFSSLKDLLNC
YRMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVHISPTLQRHNNVNQMVFHKI
RNEDLIFNESLGQGTFTKIFKGIRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM
MSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLGVAKQLAWA
MHFLEEKSLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVP
PECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDKHQLPAPKWTEL
ANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRD
PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE
ILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQI
CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFW
YAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPVEFMRMIGNDKQGQMIVFHLIE
LLKNNGRLPRPEGCPDEIYIIMTECWNNNVNQRPSFRDLALRVDQIRDSMAA
NT seq
3399 nt
NT seq
+upstream
nt +downstream
nt
atgggaatggcttgccttacaatgacagaaatggaagcaacttccacacctcctgtacat
cagaatggagatattcctggaaatgctagttctgtgaagcaagtagatccagtccttcag
gtatatctgtaccactcccttggaaaagctgaaggagtttatctgaagtttccaactgga
gagtatgttgcagaagaaatttgtgttgctgcttctaaagcttgtggtattacacctgtg
tatcataatatgtttgctttaatgagtgaagcagaaagaatctggtatccacccaaccat
gtcttccacatagatgagtcaaccagccataatatactctacagaataagattttacttt
cctcactggtattgcagtggcagcaacagaacctatcgatacggaatatctcgtggggct
gaagcacctcttcttgatgactttgtcatgtcttacctctttgctcagtggcggcatgat
tttgtgcatggatggataaaagtacctgtgactcatgaaacacaggaagaatgtcttggg
atggcggtgttagatatgatgcgaatagctaaagagaaggatcagacacccctggctatc
tacaattccatcagctataagacattcttaccaaaatgcgttcgagcaaagatccaagac
taccatattttgacccggaagcgaataaggtaccgatttcgcagatttattcagcagttc
agtcaatgcaaagccactgccaggaacttgaaacttaagtatcttataaatctggaaact
cttcagtctgccttctacacagagcaatttgaagtaaaagaatctgcaagaggtccttca
ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga
gggaaacataaagaaagtgagacactgacagaacaggatttacagttatattgtgatttt
cctgatattattgatgtcagtattaagcaagcaaaccaggaatgctcaaatgaaagtaga
attgtaactatccataagcaagatgggaaaattttggaaattgaacttagctcattaaga
gaagctttgtcatttgtatcattaattgatggatattatagactaactgcagatgcacac
cattacctctgtaaagaagtagcaccaccagcagtgcttgagaatatacagagcaactgt
catggcccaatttcaatggattttgcaattagtaaactgaagaaagcgggtaatcagact
ggattatatgtacttcgatgtagtcctaaggactttgataaatattttctgacctttgct
gttgagcgagataatatcattgaatataagcattgtttgattacaaagaatgagaacaga
gagtacaacctcagtgggactaagaggaacttcagcagtcttaaagaccttctgaactgc
taccggatggaaactgttcgctcagacaatataattttccagtttactaaatgctgtccc
ccaaagccaaaagataagtcaaaccttctagtcttcagaacaaatggtgtttctgatgtt
cacatctcaccaacgttacagaggcataataatgtgaaccaaatggtgttccacaaaatc
agaaatgaagatttgatatttaatgaaagccttggccaaggtacttttaccaaaattttt
aaaggtataagaagagaagtaggagattatggtcagctgcatgaaacagaagttcttttg
aaagttctggataaagcacatagaaactattcagagtctttctttgaagcagcaagcatg
atgagtcagctttctcacaagcatttggttttgaattacggagtatgtgtctgtggagag
gagaatattctggttcaagagtttgttaaatttggatcactagatacgtatctgaaaaaa
aataaaaattccataaacatattatggaaactcggagtggctaaacagttggcatgggca
atgcattttctagaagagaaatcccttattcacggaaatgtatgtgccaaaaatattcta
cttatcagagaagaagataggaaaacaggaaatcctcctttcatcaaacttagtgaccct
ggcatcagcattacagttttaccaaaggacattcttcaggagagaataccttgggtacca
cctgaatgtattgaaaatcccaaaaatctaaatctggcaacagacaaatggagttttggt
accactctgtgggaaatttgcagtggaggagataagcctctaagtgctctggattctcaa
agaaagctacagttttatgaagataagcatcagcttcctgcaccaaagtggacagaatta
gcaaaccttataaataattgcatggattatgaaccagatttcaggccttctttcagagcc
atcatacgagatcttaacagtttgtttactccggattatgaactattaacagaaaatgac
atgctaccaaacatgagaataggtgccctaggattttctggtgcttttgaagacagagac
cctacacagtttgaggagagacatttgaaatttctacagcaactcggcaagggtaacttt
gggagtgtggagatgtgccgctatgaccccctacaagacaacactggagaggtggtggct
gttaaaaagctacagcacagcacggaagagcacctcagggattttgaaagggaaattgaa
atcctgaaatccttgcagcatgacaacattgtaaagtacaagggagtatgctacagtgct
ggtcggcgtaacctaagattaattatggaatatttgccatatggaagtttacgggactat
ctccaaaaacataaagaacggatcgatcacaaaaaacttctgcagtacacatctcagata
tgcaagggtatggagtatcttggtacaaaaaggtatatccacagagacctagcaacaaga
aatatattggtggaaaatgagaaccgagttaaaattggagattttggattaaccaaagtc
ttgccacaagacaaagaatactacaaagtaaaagaaccaggtgaaagccccatattctgg
tatgctccagaatcactgaccgagagcaagttttctgtggcctcagatgtttggagtttt
ggtgtggttctgtatgaacttttcacatatattgagaagagtaaaagtccaccagtggaa
tttatgcgaatgattggcaatgacaagcaaggacagatgattgtgttccatctgatagag
ctcctgaagaataatgggagattgccaaggcctgaagggtgcccagatgagatatatatt
atcatgacagaatgctggaacaacaatgtaaatcagcgtccctccttcagggacctggca
cttcgagtggatcaaatacgggacagtatggctgcgtga
DBGET
integrated database retrieval system