Nyctereutes procyonoides (raccoon dog): 129499911 Help Entry 129499911         CDS       T09008                                  Symbol JAK2 Name (RefSeq) tyrosine-protein kinase JAK2   KO K04447   Janus kinase 2 [EC:2.7.10.2] Organism npo  Nyctereutes procyonoides (raccoon dog) Pathway npo01521   EGFR tyrosine kinase inhibitor resistance npo04062   Chemokine signaling pathway npo04148   Efferocytosis npo04151   PI3K-Akt signaling pathway npo04217   Necroptosis npo04550   Signaling pathways regulating pluripotency of stem cells npo04630   JAK-STAT signaling pathway npo04658   Th1 and Th2 cell differentiation npo04659   Th17 cell differentiation npo04725   Cholinergic synapse npo04917   Prolactin signaling pathway npo04920   Adipocytokine signaling pathway npo04933   AGE-RAGE signaling pathway in diabetic complications npo04935   Growth hormone synthesis, secretion and action npo05140   Leishmaniasis npo05145   Toxoplasmosis npo05152   Tuberculosis npo05161   Hepatitis B npo05164   Influenza A npo05167   Kaposi sarcoma-associated herpesvirus infection npo05168   Herpes simplex virus 1 infection npo05200   Pathways in cancer npo05207   Chemical carcinogenesis - receptor activation npo05235   PD-L1 expression and PD-1 checkpoint pathway in cancer npo05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:npo00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     129499911 (JAK2)    04151 PI3K-Akt signaling pathway     129499911 (JAK2)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     129499911 (JAK2)   09143 Cell growth and death    04217 Necroptosis     129499911 (JAK2)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     129499911 (JAK2)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     129499911 (JAK2)    04659 Th17 cell differentiation     129499911 (JAK2)    04062 Chemokine signaling pathway     129499911 (JAK2)   09152 Endocrine system    04920 Adipocytokine signaling pathway     129499911 (JAK2)    04917 Prolactin signaling pathway     129499911 (JAK2)    04935 Growth hormone synthesis, secretion and action     129499911 (JAK2)   09156 Nervous system    04725 Cholinergic synapse     129499911 (JAK2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     129499911 (JAK2)    05207 Chemical carcinogenesis - receptor activation     129499911 (JAK2)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     129499911 (JAK2)   09172 Infectious disease: viral    05161 Hepatitis B     129499911 (JAK2)    05164 Influenza A     129499911 (JAK2)    05168 Herpes simplex virus 1 infection     129499911 (JAK2)    05167 Kaposi sarcoma-associated herpesvirus infection     129499911 (JAK2)   09171 Infectious disease: bacterial    05152 Tuberculosis     129499911 (JAK2)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     129499911 (JAK2)    05140 Leishmaniasis     129499911 (JAK2)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     129499911 (JAK2)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     129499911 (JAK2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     129499911 (JAK2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:npo01001]     129499911 (JAK2) Enzymes [BR:npo01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      129499911 (JAK2) Protein kinases [BR:npo01001]  Non-receptor tyrosine kinases   JAK family [OT]    129499911 (JAK2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 FERM_F1 SH2_1 Jak1_Phl ABC1 FERM_C_FAK1 RIO1 Kinase-like FERM_M Motif Other DBs NCBI-GeneID:  129499911 NCBI-ProteinID:  XP_055165942 LinkDB All DBs Position Unknown AA seq 1132 aa AA seqDB search MGMACLTMTEMEGTSESPIHQNGDIPGNANSVKQIDPLLQVYLYHSLEKAEEEYLKFPTG EYVAEEICVAASKACGITPVYHSMFALMSETERIWYPPNHVFHIDESTKHNVLYRIRFYF PYWYCNGSNRTYRHGISRGAEAPLLDDFVMAYLFAQWRHDFLHGWIKIPVTHETQEECLG MAVLDMMRLAKEKDQTPLDIYSSISYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIEQF SHCKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSR GKRKESETLTEQDLQLYCDFPDIIDVTIKQASQEGSNESRIVTIHKQDGKNLEIELSSLR EALSFVSLIDGYYRLTADAHHYLCKEVAPPMVLENIQSNCHGPILMDFAISKLKKAGNQT GLYVLRCSPKDFNKYFLTFAIERENVIEYKHCLITKNENGEYNLSGTKKSFRNLKDLLNC YHMETVRSDSIIFQFTKCCPPKLKDKSNLLVFRTNGVSDVPTSPTLQRHNNVNQMVFHKI RNEDLMFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM MSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINIFWKLEVAKQLAWA MHFLEEKALIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVP PECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTEL ANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFPGAFEDQD PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE ILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQI CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFW YAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIE LLKNNGRLPRPDGCPDEIYLIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG NT seq 3399 nt NT seq  +upstreamnt  +downstreamnt atgggaatggcttgccttacaatgacagaaatggaaggaacatccgaatctcctatacat cagaatggtgatattcctggaaatgctaattctgtgaagcaaatagacccactcctacag gtgtatctttatcattctcttgagaaagctgaagaagaatatctgaagtttccaactggg gagtatgttgcagaagaaatttgtgttgctgcttctaaagcttgtggaatcacacctgtg tatcatagtatgtttgctttaatgagtgaaacagaaaggatctggtatccacccaaccat gtcttccatattgatgaatcaaccaagcacaatgtactctacagaataagattttacttc ccttactggtattgtaacggcagcaacagaacctatcggcacggaatatctcgaggtgct gaagctcctcttcttgacgactttgtcatggcttatctttttgctcagtggcggcatgat tttttacatggatggataaaaatacccgtgactcatgaaacacaggaagaatgtcttgga atggctgtgctagatatgatgagactagccaaagagaaggatcaaaccccattggatatc tatagctctatcagctacaagacattcttacccaaatgtgttcgagcaaagattcaagac tatcatattttgacaaggaaacgaataaggtacagatttcgcagatttattgagcaattc agccattgcaaagccactgccagaaacttgaaacttaagtaccttataaatctggaaact cttcagtctgccttctacacagagcaatttgaagtaaaagaacctggaagaggtccttca ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga gggaaacgtaaagaaagtgagacactgacagaacaggatttacagttatattgtgacttt cctgatattattgatgttactattaagcaagcaagccaagaaggctcaaatgaaagtaga attgtaactatccataagcaagatggtaaaaatctggaaattgaacttagctcattaaga gaagctttgtcctttgtgtcattaattgatggctattatagattaactgcagatgcacat cattacctctgtaaagaagtagcacctccaatggtccttgaaaatatacaaagcaactgt catggcccaattttaatggattttgctatcagtaaactgaagaaagcaggtaatcagact ggactctatgtacttcgatgcagccctaaggactttaataaatatttcctgacttttgcc attgagcgagaaaatgtcattgaatataagcactgtttgattacaaaaaatgaaaatgga gaatacaacctcagtgggaccaagaagagcttccgtaatcttaaagatcttttgaactgc taccacatggagactgttcgctcagacagcataattttccagtttaccaaatgctgtccc ccaaaattgaaagataagtcaaaccttctagtcttcagaaccaatggcgtttctgatgta ccaacatcaccaacattacagaggcataataatgtgaaccaaatggtgttccacaaaatc agaaatgaagatttgatgtttaacgaaagtcttggccaaggcacttttacaaaaattttt aaaggtgtgagaagagaagtaggagactatggtcaactgcatgaaacagaagttctttta aaagttcttgataaagcacacagaaattattcagagtctttctttgaagcagccagcatg atgagccagctttctcataagcatctggttttaaattacggagtatgtgtctgtggagag gagaatattctggttcaggaatttgtaaaatttggatcattagatacatatctgaaaaag aataagaattctataaatatattttggaaacttgaagtggctaaacagttggcatgggca atgcattttctagaagagaaagcacttattcatggaaatgtgtgtgccaaaaatattctg cttatcagagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgatcct ggcattagtattacagttttgccaaaggacattcttcaggagagaataccatgggtacca cctgaatgcattgaaaatcctaaaaatctaaatttggcgacagacaaatggagttttggt actactttgtgggaaatctgcagtggaggagataagcctctgagtgctttggattctcag agaaagctacagttttatgaagataggcaccagcttcctgcaccaaagtggacagaatta gcaaatcttattaataattgtatggattatgaaccagattttagaccttctttcagagcc atcatacgagatcttaatagtttgtttactccagattatgaactattaacagaaaatgac atgttaccaaatatgagaattggtgccctagggtttcctggtgcttttgaagatcaagac cctacacagtttgaagagagacacttgaaatttctacagcaacttggcaagggtaatttt ggcagtgtggagatgtgccgatatgaccctctacaagacaacactggggaggtggtagct gtgaagaagctccagcacagtactgaagagcacctgagagactttgagagggaaattgaa atccttaaatccctgcagcatgacaacattgtaaagtacaagggagtgtgctacagtgct ggccggcgtaatctaagattaattatggaatatttaccatatggaagtttacgagactac ctccaaaaacataaagaacgaatagatcataaaaaacttctgcagtatacatctcagata tgcaagggcatggagtatcttggtacaaaaaggtatatacacagggatctggcaacaagg aatatattggtggagaatgaaaacagggttaaaattggagattttgggttaaccaaagtc ttgccacaagacaaagaatactacaaagtgaaagaacctggtgaaagtcccatattctgg tatgctccagagtcattgacagagagcaagttttctgtggcttcagatgtctggagcttt ggagtggttctatatgaacttttcacatatattgagaagagtaaaagtccaccagcggaa tttatgcgtatgattggcaatgacaagcaaggacagatgattgtgtttcatttgatagaa ctcctaaagaataatggaagactaccaagaccagatggatgcccagatgagatttatttg atcatgacagaatgctggaataataatgtgaatcagcggccctctttcagagacctagct cttcgagtggatcagataagggacaacatggctggatga

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