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Nyctereutes procyonoides (raccoon dog): 129499911
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Entry
129499911 CDS
T09008
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
npo
Nyctereutes procyonoides (raccoon dog)
Pathway
npo01521
EGFR tyrosine kinase inhibitor resistance
npo04062
Chemokine signaling pathway
npo04148
Efferocytosis
npo04151
PI3K-Akt signaling pathway
npo04217
Necroptosis
npo04550
Signaling pathways regulating pluripotency of stem cells
npo04630
JAK-STAT signaling pathway
npo04658
Th1 and Th2 cell differentiation
npo04659
Th17 cell differentiation
npo04725
Cholinergic synapse
npo04917
Prolactin signaling pathway
npo04920
Adipocytokine signaling pathway
npo04933
AGE-RAGE signaling pathway in diabetic complications
npo04935
Growth hormone synthesis, secretion and action
npo05140
Leishmaniasis
npo05145
Toxoplasmosis
npo05152
Tuberculosis
npo05161
Hepatitis B
npo05164
Influenza A
npo05167
Kaposi sarcoma-associated herpesvirus infection
npo05168
Herpes simplex virus 1 infection
npo05200
Pathways in cancer
npo05207
Chemical carcinogenesis - receptor activation
npo05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
npo05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
npo00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
129499911 (JAK2)
04151 PI3K-Akt signaling pathway
129499911 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
129499911 (JAK2)
09143 Cell growth and death
04217 Necroptosis
129499911 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
129499911 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
129499911 (JAK2)
04659 Th17 cell differentiation
129499911 (JAK2)
04062 Chemokine signaling pathway
129499911 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
129499911 (JAK2)
04917 Prolactin signaling pathway
129499911 (JAK2)
04935 Growth hormone synthesis, secretion and action
129499911 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
129499911 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
129499911 (JAK2)
05207 Chemical carcinogenesis - receptor activation
129499911 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
129499911 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
129499911 (JAK2)
05164 Influenza A
129499911 (JAK2)
05168 Herpes simplex virus 1 infection
129499911 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
129499911 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
129499911 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
129499911 (JAK2)
05140 Leishmaniasis
129499911 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
129499911 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
129499911 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
129499911 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
npo01001
]
129499911 (JAK2)
Enzymes [BR:
npo01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
129499911 (JAK2)
Protein kinases [BR:
npo01001
]
Non-receptor tyrosine kinases
JAK family [OT]
129499911 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
129499911
NCBI-ProteinID:
XP_055165942
LinkDB
All DBs
Position
Unknown
AA seq
1132 aa
AA seq
DB search
MGMACLTMTEMEGTSESPIHQNGDIPGNANSVKQIDPLLQVYLYHSLEKAEEEYLKFPTG
EYVAEEICVAASKACGITPVYHSMFALMSETERIWYPPNHVFHIDESTKHNVLYRIRFYF
PYWYCNGSNRTYRHGISRGAEAPLLDDFVMAYLFAQWRHDFLHGWIKIPVTHETQEECLG
MAVLDMMRLAKEKDQTPLDIYSSISYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIEQF
SHCKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSR
GKRKESETLTEQDLQLYCDFPDIIDVTIKQASQEGSNESRIVTIHKQDGKNLEIELSSLR
EALSFVSLIDGYYRLTADAHHYLCKEVAPPMVLENIQSNCHGPILMDFAISKLKKAGNQT
GLYVLRCSPKDFNKYFLTFAIERENVIEYKHCLITKNENGEYNLSGTKKSFRNLKDLLNC
YHMETVRSDSIIFQFTKCCPPKLKDKSNLLVFRTNGVSDVPTSPTLQRHNNVNQMVFHKI
RNEDLMFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM
MSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINIFWKLEVAKQLAWA
MHFLEEKALIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVP
PECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTEL
ANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFPGAFEDQD
PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE
ILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQI
CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFW
YAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIE
LLKNNGRLPRPDGCPDEIYLIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG
NT seq
3399 nt
NT seq
+upstream
nt +downstream
nt
atgggaatggcttgccttacaatgacagaaatggaaggaacatccgaatctcctatacat
cagaatggtgatattcctggaaatgctaattctgtgaagcaaatagacccactcctacag
gtgtatctttatcattctcttgagaaagctgaagaagaatatctgaagtttccaactggg
gagtatgttgcagaagaaatttgtgttgctgcttctaaagcttgtggaatcacacctgtg
tatcatagtatgtttgctttaatgagtgaaacagaaaggatctggtatccacccaaccat
gtcttccatattgatgaatcaaccaagcacaatgtactctacagaataagattttacttc
ccttactggtattgtaacggcagcaacagaacctatcggcacggaatatctcgaggtgct
gaagctcctcttcttgacgactttgtcatggcttatctttttgctcagtggcggcatgat
tttttacatggatggataaaaatacccgtgactcatgaaacacaggaagaatgtcttgga
atggctgtgctagatatgatgagactagccaaagagaaggatcaaaccccattggatatc
tatagctctatcagctacaagacattcttacccaaatgtgttcgagcaaagattcaagac
tatcatattttgacaaggaaacgaataaggtacagatttcgcagatttattgagcaattc
agccattgcaaagccactgccagaaacttgaaacttaagtaccttataaatctggaaact
cttcagtctgccttctacacagagcaatttgaagtaaaagaacctggaagaggtccttca
ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga
gggaaacgtaaagaaagtgagacactgacagaacaggatttacagttatattgtgacttt
cctgatattattgatgttactattaagcaagcaagccaagaaggctcaaatgaaagtaga
attgtaactatccataagcaagatggtaaaaatctggaaattgaacttagctcattaaga
gaagctttgtcctttgtgtcattaattgatggctattatagattaactgcagatgcacat
cattacctctgtaaagaagtagcacctccaatggtccttgaaaatatacaaagcaactgt
catggcccaattttaatggattttgctatcagtaaactgaagaaagcaggtaatcagact
ggactctatgtacttcgatgcagccctaaggactttaataaatatttcctgacttttgcc
attgagcgagaaaatgtcattgaatataagcactgtttgattacaaaaaatgaaaatgga
gaatacaacctcagtgggaccaagaagagcttccgtaatcttaaagatcttttgaactgc
taccacatggagactgttcgctcagacagcataattttccagtttaccaaatgctgtccc
ccaaaattgaaagataagtcaaaccttctagtcttcagaaccaatggcgtttctgatgta
ccaacatcaccaacattacagaggcataataatgtgaaccaaatggtgttccacaaaatc
agaaatgaagatttgatgtttaacgaaagtcttggccaaggcacttttacaaaaattttt
aaaggtgtgagaagagaagtaggagactatggtcaactgcatgaaacagaagttctttta
aaagttcttgataaagcacacagaaattattcagagtctttctttgaagcagccagcatg
atgagccagctttctcataagcatctggttttaaattacggagtatgtgtctgtggagag
gagaatattctggttcaggaatttgtaaaatttggatcattagatacatatctgaaaaag
aataagaattctataaatatattttggaaacttgaagtggctaaacagttggcatgggca
atgcattttctagaagagaaagcacttattcatggaaatgtgtgtgccaaaaatattctg
cttatcagagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgatcct
ggcattagtattacagttttgccaaaggacattcttcaggagagaataccatgggtacca
cctgaatgcattgaaaatcctaaaaatctaaatttggcgacagacaaatggagttttggt
actactttgtgggaaatctgcagtggaggagataagcctctgagtgctttggattctcag
agaaagctacagttttatgaagataggcaccagcttcctgcaccaaagtggacagaatta
gcaaatcttattaataattgtatggattatgaaccagattttagaccttctttcagagcc
atcatacgagatcttaatagtttgtttactccagattatgaactattaacagaaaatgac
atgttaccaaatatgagaattggtgccctagggtttcctggtgcttttgaagatcaagac
cctacacagtttgaagagagacacttgaaatttctacagcaacttggcaagggtaatttt
ggcagtgtggagatgtgccgatatgaccctctacaagacaacactggggaggtggtagct
gtgaagaagctccagcacagtactgaagagcacctgagagactttgagagggaaattgaa
atccttaaatccctgcagcatgacaacattgtaaagtacaagggagtgtgctacagtgct
ggccggcgtaatctaagattaattatggaatatttaccatatggaagtttacgagactac
ctccaaaaacataaagaacgaatagatcataaaaaacttctgcagtatacatctcagata
tgcaagggcatggagtatcttggtacaaaaaggtatatacacagggatctggcaacaagg
aatatattggtggagaatgaaaacagggttaaaattggagattttgggttaaccaaagtc
ttgccacaagacaaagaatactacaaagtgaaagaacctggtgaaagtcccatattctgg
tatgctccagagtcattgacagagagcaagttttctgtggcttcagatgtctggagcttt
ggagtggttctatatgaacttttcacatatattgagaagagtaaaagtccaccagcggaa
tttatgcgtatgattggcaatgacaagcaaggacagatgattgtgtttcatttgatagaa
ctcctaaagaataatggaagactaccaagaccagatggatgcccagatgagatttatttg
atcatgacagaatgctggaataataatgtgaatcagcggccctctttcagagacctagct
cttcgagtggatcagataagggacaacatggctggatga
DBGET
integrated database retrieval system