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Nyctereutes procyonoides (raccoon dog): 129515848
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Entry
129515848 CDS
T09008
Symbol
BRAF
Name
(RefSeq) serine/threonine-protein kinase B-raf isoform X1
KO
K04365
B-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
npo
Nyctereutes procyonoides (raccoon dog)
Pathway
npo01521
EGFR tyrosine kinase inhibitor resistance
npo01522
Endocrine resistance
npo04010
MAPK signaling pathway
npo04012
ErbB signaling pathway
npo04015
Rap1 signaling pathway
npo04024
cAMP signaling pathway
npo04062
Chemokine signaling pathway
npo04068
FoxO signaling pathway
npo04150
mTOR signaling pathway
npo04270
Vascular smooth muscle contraction
npo04510
Focal adhesion
npo04650
Natural killer cell mediated cytotoxicity
npo04720
Long-term potentiation
npo04722
Neurotrophin signaling pathway
npo04726
Serotonergic synapse
npo04730
Long-term depression
npo04810
Regulation of actin cytoskeleton
npo04910
Insulin signaling pathway
npo04914
Progesterone-mediated oocyte maturation
npo04928
Parathyroid hormone synthesis, secretion and action
npo04934
Cushing syndrome
npo05010
Alzheimer disease
npo05022
Pathways of neurodegeneration - multiple diseases
npo05034
Alcoholism
npo05160
Hepatitis C
npo05161
Hepatitis B
npo05200
Pathways in cancer
npo05205
Proteoglycans in cancer
npo05208
Chemical carcinogenesis - reactive oxygen species
npo05210
Colorectal cancer
npo05211
Renal cell carcinoma
npo05212
Pancreatic cancer
npo05213
Endometrial cancer
npo05214
Glioma
npo05215
Prostate cancer
npo05216
Thyroid cancer
npo05218
Melanoma
npo05219
Bladder cancer
npo05220
Chronic myeloid leukemia
npo05221
Acute myeloid leukemia
npo05223
Non-small cell lung cancer
npo05224
Breast cancer
npo05225
Hepatocellular carcinoma
npo05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
npo00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
129515848 (BRAF)
04012 ErbB signaling pathway
129515848 (BRAF)
04015 Rap1 signaling pathway
129515848 (BRAF)
04068 FoxO signaling pathway
129515848 (BRAF)
04024 cAMP signaling pathway
129515848 (BRAF)
04150 mTOR signaling pathway
129515848 (BRAF)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
129515848 (BRAF)
09142 Cell motility
04810 Regulation of actin cytoskeleton
129515848 (BRAF)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
129515848 (BRAF)
04062 Chemokine signaling pathway
129515848 (BRAF)
09152 Endocrine system
04910 Insulin signaling pathway
129515848 (BRAF)
04914 Progesterone-mediated oocyte maturation
129515848 (BRAF)
04928 Parathyroid hormone synthesis, secretion and action
129515848 (BRAF)
09153 Circulatory system
04270 Vascular smooth muscle contraction
129515848 (BRAF)
09156 Nervous system
04726 Serotonergic synapse
129515848 (BRAF)
04720 Long-term potentiation
129515848 (BRAF)
04730 Long-term depression
129515848 (BRAF)
04722 Neurotrophin signaling pathway
129515848 (BRAF)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
129515848 (BRAF)
05205 Proteoglycans in cancer
129515848 (BRAF)
05208 Chemical carcinogenesis - reactive oxygen species
129515848 (BRAF)
09162 Cancer: specific types
05210 Colorectal cancer
129515848 (BRAF)
05212 Pancreatic cancer
129515848 (BRAF)
05225 Hepatocellular carcinoma
129515848 (BRAF)
05226 Gastric cancer
129515848 (BRAF)
05214 Glioma
129515848 (BRAF)
05216 Thyroid cancer
129515848 (BRAF)
05221 Acute myeloid leukemia
129515848 (BRAF)
05220 Chronic myeloid leukemia
129515848 (BRAF)
05218 Melanoma
129515848 (BRAF)
05211 Renal cell carcinoma
129515848 (BRAF)
05219 Bladder cancer
129515848 (BRAF)
05215 Prostate cancer
129515848 (BRAF)
05213 Endometrial cancer
129515848 (BRAF)
05224 Breast cancer
129515848 (BRAF)
05223 Non-small cell lung cancer
129515848 (BRAF)
09172 Infectious disease: viral
05161 Hepatitis B
129515848 (BRAF)
05160 Hepatitis C
129515848 (BRAF)
09164 Neurodegenerative disease
05010 Alzheimer disease
129515848 (BRAF)
05022 Pathways of neurodegeneration - multiple diseases
129515848 (BRAF)
09165 Substance dependence
05034 Alcoholism
129515848 (BRAF)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
129515848 (BRAF)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
129515848 (BRAF)
01522 Endocrine resistance
129515848 (BRAF)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
npo01001
]
129515848 (BRAF)
Enzymes [BR:
npo01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
129515848 (BRAF)
Protein kinases [BR:
npo01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
129515848 (BRAF)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
ABC1
C1_2
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
129515848
NCBI-ProteinID:
XP_055190914
LinkDB
All DBs
Position
Unknown
AA seq
853 aa
AA seq
DB search
MAALSGGGGGGGAEQGQALFNGDMEPEAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHI
EALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLGNGTDFSVSSSASTDTVT
SSSSSSLSVLPSSLSVFQNPTDISRSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSL
KKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKT
FFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPIP
QEEASIAETALTSGSSPSAPPSDSPGPPILTSPSPSKSIPIPQPFRPADEDHRNQFGQRD
RSSSAPNVHINTIEPVNIDDLIRDQGFRSDVGSTTGLSATPPASLPGSLTNVKALQKSPG
PQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVA
VKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHL
HIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVK
SRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINN
RDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSL
PKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYDTEFSMHKLVWNRMEFPIQQK
REECFRNQNSLLPVFLLQHKYHVHTSLPTPRKEEESLSSDLLMVRHDGKKLLLQLGRLAV
ESLPVSSALLTAR
NT seq
2562 nt
NT seq
+upstream
nt +downstream
nt
atggcggcgctgagcggcggcggcggcggcggcggcgcggagcagggccaggctctgttc
aacggggacatggagcccgaggccggcgccggcgccgcggcctcttcggctgcggaccct
gccattcccgaggaggtgtggaatatcaaacaaatgattaagttgacacaggaacatata
gaagccctattggacaagtttggtggggagcataatccaccatcaatatatctggaggcc
tatgaagaatacaccagcaaactagatgccctccaacagcgagaacaacagttattggaa
tccctggggaatggaactgatttttctgtttctagctctgcatcaacggacaccgttaca
tcttcttcctcttctagtctttcagtgctaccttcatctctttcagtttttcaaaatccc
acagatatatcacggagcaatcccaagtcaccacaaaaacctatcgttagagtcttccta
cccaataaacagaggacggtggtacccgcaagatgtggagttacagtccgggacagtcta
aagaaagctctgatgatgagaggtctaatcccggagtgctgtgctgtttacagaattcag
gatggagagaagaaaccgattggctgggacactgatatttcctggctcactggagaggaa
ttgcatgtagaagtgttggaaaatgttccgcttaccacacacaactttgtacggaaaact
tttttcaccttagcattttgtgacttttgtcgaaagctgcttttccagggttttcgctgt
caaacatgtggttataaatttcaccagcgttgtagtacagaggttccactgatgtgtgtt
aattatgaccaacttgatttgctgtttgtctccaagttctttgaacaccacccaatacca
caggaggaggcctccatagcagagactgcccttacgtctggatcatccccttctgctccc
ccctccgattctcctgggcccccaattctgaccagtccatctccttcaaaatccattcca
attccacagcctttccgaccagcagatgaagatcatcgaaatcagtttggacaacgagac
cggtcctcatcagctccaaatgtgcatataaacacaatagaacccgtcaacattgatgac
ttgattagagaccaagggtttcgtagtgatgtaggatcaaccacaggtttgtctgccacc
ccccctgcctcattgcctggctcactcactaatgtaaaagcattacagaaatctccagga
cctcagcgggaaagaaaatcatcttcatcctcagaagataggaatcgaatgaaaacactt
ggtagacgggattcaagtgatgattgggagatacctgatgggcagatcacagtgggacag
agaattggatccgggtcatttgggacagtctacaagggaaagtggcatggtgacgtggca
gtgaaaatgttgaatgtgacagcacccacacctcagcagttacaggccttcaaaaatgaa
gtaggagtactcaggaaaactcgacatgtgaatatcctactctttatgggctattcaaca
aagccccaactggctattgttacccagtggtgtgagggctccagcttatatcaccatctc
cacatcattgagaccaaatttgagatgataaagcttatagatattgcacggcagactgca
cagggcatggattacttacacgccaagtcaatcatccacagagacctcaagagtaataat
atttttcttcatgaagacctcacagtaaaaataggtgattttggtctagccacagtgaaa
tctcgatggagtgggtcccatcagtttgaacagttgtctggatccattttgtggatggca
ccagaagtgatccgaatgcaagacaaaaacccatatagcttccagtcagatgtatacgca
tttgggattgttctatatgaattgatgacagggcagttaccttattcaaacatcaacaac
agggaccagataatttttatggtgggacgaggatatctttctccagatctcagtaaggta
cggagtaactgtccaaaagccatgaagagattgatggcagagtgcctaaaaaagaaaaga
gatgagaggccactctttccccaaattctcgcctctattgagctgctggcccgctcattg
ccaaaaattcaccgcagtgcatcagaaccctccttgaatcgggctggcttccaaacagag
gattttagtctctatgcttgtgcttctccaaaaacacccatccaggcagggggatacgat
acagaattttcaatgcataagctggtgtggaacagaatggaatttcccatccaacaaaag
agggaagaatgttttaggaaccagaattctctgctgccagtgtttcttcttcaacacaaa
taccacgtgcatacaagtctgcccactcccaggaaggaagaggagagcctgagttctgac
cttttgatggtcaggcatgatggaaagaaactgctgctacagcttgggagattggctgtg
gagagcctgcccgtcagctctgcccttctaaccgccagatga
DBGET
integrated database retrieval system