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Ochotona princeps (American pika): 101526188
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Entry
101526188 CDS
T07609
Symbol
BRAF
Name
(RefSeq) serine/threonine-protein kinase B-raf isoform X2
KO
K04365
B-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
opi
Ochotona princeps (American pika)
Pathway
opi01521
EGFR tyrosine kinase inhibitor resistance
opi01522
Endocrine resistance
opi04010
MAPK signaling pathway
opi04012
ErbB signaling pathway
opi04015
Rap1 signaling pathway
opi04024
cAMP signaling pathway
opi04062
Chemokine signaling pathway
opi04068
FoxO signaling pathway
opi04150
mTOR signaling pathway
opi04270
Vascular smooth muscle contraction
opi04510
Focal adhesion
opi04650
Natural killer cell mediated cytotoxicity
opi04720
Long-term potentiation
opi04722
Neurotrophin signaling pathway
opi04726
Serotonergic synapse
opi04730
Long-term depression
opi04810
Regulation of actin cytoskeleton
opi04910
Insulin signaling pathway
opi04914
Progesterone-mediated oocyte maturation
opi04928
Parathyroid hormone synthesis, secretion and action
opi04934
Cushing syndrome
opi05010
Alzheimer disease
opi05022
Pathways of neurodegeneration - multiple diseases
opi05034
Alcoholism
opi05160
Hepatitis C
opi05161
Hepatitis B
opi05200
Pathways in cancer
opi05205
Proteoglycans in cancer
opi05208
Chemical carcinogenesis - reactive oxygen species
opi05210
Colorectal cancer
opi05211
Renal cell carcinoma
opi05212
Pancreatic cancer
opi05213
Endometrial cancer
opi05214
Glioma
opi05215
Prostate cancer
opi05216
Thyroid cancer
opi05218
Melanoma
opi05219
Bladder cancer
opi05220
Chronic myeloid leukemia
opi05221
Acute myeloid leukemia
opi05223
Non-small cell lung cancer
opi05224
Breast cancer
opi05225
Hepatocellular carcinoma
opi05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
opi00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101526188 (BRAF)
04012 ErbB signaling pathway
101526188 (BRAF)
04015 Rap1 signaling pathway
101526188 (BRAF)
04068 FoxO signaling pathway
101526188 (BRAF)
04024 cAMP signaling pathway
101526188 (BRAF)
04150 mTOR signaling pathway
101526188 (BRAF)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
101526188 (BRAF)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101526188 (BRAF)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
101526188 (BRAF)
04062 Chemokine signaling pathway
101526188 (BRAF)
09152 Endocrine system
04910 Insulin signaling pathway
101526188 (BRAF)
04914 Progesterone-mediated oocyte maturation
101526188 (BRAF)
04928 Parathyroid hormone synthesis, secretion and action
101526188 (BRAF)
09153 Circulatory system
04270 Vascular smooth muscle contraction
101526188 (BRAF)
09156 Nervous system
04726 Serotonergic synapse
101526188 (BRAF)
04720 Long-term potentiation
101526188 (BRAF)
04730 Long-term depression
101526188 (BRAF)
04722 Neurotrophin signaling pathway
101526188 (BRAF)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101526188 (BRAF)
05205 Proteoglycans in cancer
101526188 (BRAF)
05208 Chemical carcinogenesis - reactive oxygen species
101526188 (BRAF)
09162 Cancer: specific types
05210 Colorectal cancer
101526188 (BRAF)
05212 Pancreatic cancer
101526188 (BRAF)
05225 Hepatocellular carcinoma
101526188 (BRAF)
05226 Gastric cancer
101526188 (BRAF)
05214 Glioma
101526188 (BRAF)
05216 Thyroid cancer
101526188 (BRAF)
05221 Acute myeloid leukemia
101526188 (BRAF)
05220 Chronic myeloid leukemia
101526188 (BRAF)
05218 Melanoma
101526188 (BRAF)
05211 Renal cell carcinoma
101526188 (BRAF)
05219 Bladder cancer
101526188 (BRAF)
05215 Prostate cancer
101526188 (BRAF)
05213 Endometrial cancer
101526188 (BRAF)
05224 Breast cancer
101526188 (BRAF)
05223 Non-small cell lung cancer
101526188 (BRAF)
09172 Infectious disease: viral
05161 Hepatitis B
101526188 (BRAF)
05160 Hepatitis C
101526188 (BRAF)
09164 Neurodegenerative disease
05010 Alzheimer disease
101526188 (BRAF)
05022 Pathways of neurodegeneration - multiple diseases
101526188 (BRAF)
09165 Substance dependence
05034 Alcoholism
101526188 (BRAF)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
101526188 (BRAF)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101526188 (BRAF)
01522 Endocrine resistance
101526188 (BRAF)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
opi01001
]
101526188 (BRAF)
Enzymes [BR:
opi01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101526188 (BRAF)
Protein kinases [BR:
opi01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
101526188 (BRAF)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
ABC1
C1_2
Pkinase_fungal
Kdo
Motif
Other DBs
NCBI-GeneID:
101526188
NCBI-ProteinID:
XP_004594410
LinkDB
All DBs
Position
7A:3379593..3498966
Genome browser
AA seq
762 aa
AA seq
DB search
MAALSGGGGAEQGQALFNGDMESEAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEAL
LDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLGNGTDFSVSSSASTDTVTSSS
SSSLSVLPSSLSVFQNPTDVSRSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKA
LMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFT
LAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPVPQEE
ASLAETALASGSSPSAPPTDSLGPQILTTPSPSKSIPIPQPFRPAEEDHRNQFGQRDRSS
SAPNVHINTIEPVNIDDLIRDQGFRGDGGSTTGLSATPPASLPGSLTNVKALQKSPGPQR
ERKSSSSSEDRSRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKM
LNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHII
ETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRW
SGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYLNINNRDQ
IIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKI
HRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGAFPVH
NT seq
2289 nt
NT seq
+upstream
nt +downstream
nt
atggcggcgctgagtggcggcggcggcgcggagcagggccaggctctgttcaacggggac
atggagtccgaggccggcgccggcgccgcggcctcttcggctgcggaccctgccattccc
gaggaggtgtggaatatcaaacagatgattaagttgacacaggaacatatagaggccctc
ttggacaaatttggtggggagcataatccaccatcaatatatctggaggcctatgaagaa
tacaccagcaagctagatgcactccagcaaagagagcagcagttgttggaatccctgggg
aatggaactgatttttctgtttctagctcagcatcaacggacaccgttacgtcttcttcc
tcttctagcctttcagtgctaccttcatctctttcagtttttcaaaatcccacagatgtg
tcacggagcaaccccaagtccccacaaaaacctatcgttagagtcttcctgcccaacaaa
cagaggacagtggtacctgcaagatgtggagttacagtccgagacagtctaaagaaagca
ctgatgatgagagggctaatcccagaatgctgtgctgtttacagaattcaggatggagag
aagaaaccaattggctgggacactgacatttcctggcttactggagaagaactacatgta
gaagtattggagaatgttccactcacaacgcacaactttgtacggaaaacttttttcacc
ttagcgttttgtgacttctgtcgaaagctgctcttccagggtttccgctgtcaaacgtgt
ggttacaaatttcaccagcgttgcagcacggaggtgccgctgatgtgtgttaattatgac
caacttgatttgctgtttgtctccaagttctttgaacaccacccagtaccacaggaggag
gcctccctagcagagacagccctcgcctctggatcctccccctcggctcctcccacagac
tcccttgggccccaaattctcaccactccgtctccttcaaaatccattccaattccacag
cccttccgaccagcggaagaagaccatcgaaatcagtttgggcaacgagatcggtcatca
tcagcccccaatgttcatattaacacaatagaacctgttaatattgatgacttgattaga
gaccaagggtttcgtggtgatggaggctcaaccacaggtttatctgccactccccccgcc
tcgctacctggctcactcactaacgtgaaagccttacagaaatcccccgggcctcagcgg
gaaaggaagtcctcttcgtcctcagaagacaggagtcgaatgaaaacccttggtagacgg
gattcaagtgatgactgggagattcctgatgggcagattaccgtgggacagagaattgga
tctgggtcatttggaaccgtctataagggaaaatggcacggtgatgtggcagtaaaaatg
ttgaatgtgacagcacctacacctcagcagttacaggccttcaaaaatgaagtaggagta
ctcaggaaaacacgacatgtgaatatcctacttttcatgggctattccacaaaaccacaa
ctagctattgttacccagtggtgtgagggctccagtttatatcaccatctgcacatcata
gagaccaaatttgagatgatcaaacttatagacattgcacgacagactgcacagggcatg
gattacttacacgccaagtcaatcatccacagagacctcaagagtaataatatatttctt
catgaagacctcacagtaaaaataggtgattttggtctagccacagtgaaatctcgatgg
agtgggtcccatcagtttgagcagttatctggatccattctgtggatggcaccagaagta
attagaatgcaagacaaaaacccgtatagctttcagtcagatgtatatgcatttgggatt
gttctgtatgaattgatgactggacaattaccttatttaaacatcaacaacagggaccag
atcatttttatggtgggacgtggatacctgtctccagatctcagtaaggtacggagtaac
tgtccaaaagccatgaagagattaatggcagagtgcctcaaaaagaaaagagatgagaga
ccactcttcccccagattctcgcctctatcgagctgctggcccgctcattgccaaaaatt
caccgcagtgcgtcagaaccctccttgaatcgggctggtttccagacggaggattttagt
ctgtacgcttgtgcttctccaaaaacacccatccaggcagggggctatggtgcgtttcct
gtccactga
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integrated database retrieval system