Svoboda
|
Graniru
|
BBC Russia
|
Golosameriki
|
Facebook
Papio anubis (olive baboon): 101007171
Help
Entry
101007171 CDS
T07474
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2 isoform X4
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
panu
Papio anubis (olive baboon)
Pathway
panu01521
EGFR tyrosine kinase inhibitor resistance
panu04062
Chemokine signaling pathway
panu04148
Efferocytosis
panu04151
PI3K-Akt signaling pathway
panu04217
Necroptosis
panu04550
Signaling pathways regulating pluripotency of stem cells
panu04630
JAK-STAT signaling pathway
panu04658
Th1 and Th2 cell differentiation
panu04659
Th17 cell differentiation
panu04725
Cholinergic synapse
panu04917
Prolactin signaling pathway
panu04920
Adipocytokine signaling pathway
panu04933
AGE-RAGE signaling pathway in diabetic complications
panu04935
Growth hormone synthesis, secretion and action
panu05140
Leishmaniasis
panu05145
Toxoplasmosis
panu05152
Tuberculosis
panu05161
Hepatitis B
panu05164
Influenza A
panu05167
Kaposi sarcoma-associated herpesvirus infection
panu05168
Herpes simplex virus 1 infection
panu05200
Pathways in cancer
panu05207
Chemical carcinogenesis - receptor activation
panu05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
panu05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
panu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
101007171 (JAK2)
04151 PI3K-Akt signaling pathway
101007171 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
101007171 (JAK2)
09143 Cell growth and death
04217 Necroptosis
101007171 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
101007171 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
101007171 (JAK2)
04659 Th17 cell differentiation
101007171 (JAK2)
04062 Chemokine signaling pathway
101007171 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
101007171 (JAK2)
04917 Prolactin signaling pathway
101007171 (JAK2)
04935 Growth hormone synthesis, secretion and action
101007171 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
101007171 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101007171 (JAK2)
05207 Chemical carcinogenesis - receptor activation
101007171 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101007171 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
101007171 (JAK2)
05164 Influenza A
101007171 (JAK2)
05168 Herpes simplex virus 1 infection
101007171 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
101007171 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
101007171 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
101007171 (JAK2)
05140 Leishmaniasis
101007171 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101007171 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
101007171 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101007171 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
panu01001
]
101007171 (JAK2)
Enzymes [BR:
panu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
101007171 (JAK2)
Protein kinases [BR:
panu01001
]
Non-receptor tyrosine kinases
JAK family [OT]
101007171 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2_1
Jak1_Phl
FERM_F2
SH2
ABC1
FERM_C_FAK1
RIO1
Kinase-like
Motif
Other DBs
NCBI-GeneID:
101007171
NCBI-ProteinID:
XP_021783201
Ensembl:
ENSPANG00000025145
LinkDB
All DBs
Position
13:33943189..34099035
Genome browser
AA seq
950 aa
AA seq
DB search
MEYLEVLKLLFLMTLSCLTSLLSYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQQFSQ
CKATARNLKLKYLINLETLQSAFYTEKFEVKEPGSGPSGEEIFATIIITGNGGIQWSRGK
HKESETLTEQDLQLYCDFPNIIDVSIKQANQEGSDESRVVTIHKQDGKNLEIELSSLREA
LSFVSLIDGYYRLTADAHHYLCKEVAPPTVLENIQSNCHGPISMDFAISKLKKAGNQTGL
YVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLSGTKKNFSSLKDLLNCYQ
METVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRN
EDLIFNESLGQGTFTKIFKGIRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMS
KLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMH
FLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPE
CIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELAN
LINNCMDYEPDFRPSFRAVIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDPT
QFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEIL
KSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQICK
GMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYA
PESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELL
KNNGRLPRPDGCPDEIYMIMTECWNNNVNLRPSFRDLALRVDQIRDNMAG
NT seq
2853 nt
NT seq
+upstream
nt +downstream
nt
atggaatatctcgaggtgctgaagctcctcttcttgatgactttgtcatgtcttacctct
ttgctcagctacaagacattcttaccaaaatgtattcgagcaaagatccaagactatcat
attttgacaaggaagcgaataaggtacagatttcgcagatttattcagcagttcagccaa
tgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaaccctgcag
tctgccttctacacagagaaatttgaagtaaaagaacctggaagtggtccttcaggtgag
gagatttttgcaaccattataataactggaaacggtggaattcagtggtcaagagggaaa
cataaagaaagtgagacactgacagaacaggatttacagttatattgcgattttcctaat
attattgatgtcagtattaagcaagcaaaccaagagggttcagatgaaagccgagttgta
actatccataagcaagatggtaaaaatctggaaattgaacttagctcattaagggaagct
ttgtctttcgtgtcattaattgatggatattatagattaactgcagatgcacatcattac
ctctgtaaagaagtagcacctccaacagtgcttgaaaatatacaaagcaactgtcatggc
ccaatttcgatggattttgccattagtaaactgaagaaagcaggtaatcagactggactg
tatgtacttcgatgcagtcctaaggactttaataaatattttctgacttttgctgtcgag
cgagaaaatgtcattgaatataaacactgtttgattacaaaaaatgagaatgaagagtac
aacctcagtgggacaaagaagaacttcagcagtcttaaagatcttttgaattgttaccag
atggaaaccgttcgctcagacaatataattttccagtttactaagtgctgtcccccaaag
ccaaaagataaatcaaaccttctagtcttcagaacgaatggtgtttctgatgtaccaacc
tcaccaacattacagaggcctactcatatgaaccaaatggtgtttcacaaaatcagaaat
gaagatttgatatttaatgaaagccttggtcaaggcacttttacaaagatttttaaaggc
atacgaagagaagtaggagactatggtcaacttcatgaaacagaagttcttttaaaagtt
ctggataaagcacatagaaactattcagagtctttctttgaagcagcaagcatgatgagc
aagctttctcacaagcatttggttttaaattatggagtatgtgtctgtggagaggagaat
attctggttcaggagtttgtaaaatttggatcactcgatacatacctgaaaaagaataaa
aattgtataaatatattatggaaacttgaagttgcaaaacagttggcatgggccatgcat
tttctagaagaaaacacccttattcatgggaatgtgtgcgccaaaaatattctgcttatc
agagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgatcctggcatt
agtattacagttttgccaaaggacattcttcaggagagaataccatgggtaccacctgaa
tgcattgaaaatcctaaaaatttaaatttggcaacagacaaatggagttttggtaccact
ttgtgggaaatctgcagtggaggagataaacctctaagtgccctggattctcaaagaaag
ctgcaattttatgaagataggcaccagcttcctgcaccaaagtgggcagaattagcaaac
cttataaataattgtatggattatgaacccgatttcaggccttctttcagagccgtcata
cgagatcttaacagtttgtttactccagattatgaactattaacagaaaatgacatgtta
ccaaatatgaggataggtgccctagggttttctggtgcctttgaagacagggatcctaca
cagtttgaagagagacatttgaaatttctacagcaactcggcaagggtaattttgggagt
gtggagatgtgccggtatgaccctctacaggacaacactggggaggtggtggctgtaaaa
aagcttcagcatagtactgaagagcacctgagagactttgaaagggaaattgaaatcctg
aaatccctacagcatgacaacattgtaaagtacaagggagtgtgctacagtgctggtcgg
cgtaatctaaaattaattatggaatatttaccatatggaagtttacgagactatcttcaa
aaacataaagaacggatagatcacaaaaaacttctgcagtacacatctcagatatgcaag
ggtatggagtatcttggtacaaaaaggtatatccacagggatctggcaacaagaaatata
ttggtggagaatgagaacagagttaaaattggagattttgggttaaccaaagtcttgcca
caagacaaagaatactataaagtaaaagaacctggtgaaagtcccatattctggtatgct
ccagaatcactgacagagagcaagttttctgtggcctcagatgtttggagctttggagtg
gttctgtatgaacttttcacatacattgagaagagtaaaagtccaccagcggaatttatg
cgtatgattggcaatgataaacaaggacagatgatcgtgttccatttgatagaacttttg
aagaataatggaagattaccaagaccagatggatgcccagatgagatttatatgatcatg
acagaatgctggaacaataatgtaaatctacgcccctcctttagagatctagctcttcga
gtggatcaaataagggataacatggctggatga
DBGET
integrated database retrieval system