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Phyllostomus discolor (pale spear-nosed bat): 114496018
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Entry
114496018 CDS
T07739
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
pdic
Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic01521
EGFR tyrosine kinase inhibitor resistance
pdic04062
Chemokine signaling pathway
pdic04148
Efferocytosis
pdic04151
PI3K-Akt signaling pathway
pdic04217
Necroptosis
pdic04550
Signaling pathways regulating pluripotency of stem cells
pdic04630
JAK-STAT signaling pathway
pdic04658
Th1 and Th2 cell differentiation
pdic04659
Th17 cell differentiation
pdic04725
Cholinergic synapse
pdic04917
Prolactin signaling pathway
pdic04920
Adipocytokine signaling pathway
pdic04933
AGE-RAGE signaling pathway in diabetic complications
pdic04935
Growth hormone synthesis, secretion and action
pdic05140
Leishmaniasis
pdic05145
Toxoplasmosis
pdic05152
Tuberculosis
pdic05161
Hepatitis B
pdic05164
Influenza A
pdic05167
Kaposi sarcoma-associated herpesvirus infection
pdic05168
Herpes simplex virus 1 infection
pdic05200
Pathways in cancer
pdic05207
Chemical carcinogenesis - receptor activation
pdic05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
pdic05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pdic00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
114496018 (JAK2)
04151 PI3K-Akt signaling pathway
114496018 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
114496018 (JAK2)
09143 Cell growth and death
04217 Necroptosis
114496018 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
114496018 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
114496018 (JAK2)
04659 Th17 cell differentiation
114496018 (JAK2)
04062 Chemokine signaling pathway
114496018 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
114496018 (JAK2)
04917 Prolactin signaling pathway
114496018 (JAK2)
04935 Growth hormone synthesis, secretion and action
114496018 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
114496018 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
114496018 (JAK2)
05207 Chemical carcinogenesis - receptor activation
114496018 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
114496018 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
114496018 (JAK2)
05164 Influenza A
114496018 (JAK2)
05168 Herpes simplex virus 1 infection
114496018 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
114496018 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
114496018 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
114496018 (JAK2)
05140 Leishmaniasis
114496018 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
114496018 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
114496018 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
114496018 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pdic01001
]
114496018 (JAK2)
Enzymes [BR:
pdic01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
114496018 (JAK2)
Protein kinases [BR:
pdic01001
]
Non-receptor tyrosine kinases
JAK family [OT]
114496018 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
114496018
NCBI-ProteinID:
XP_028367020
LinkDB
All DBs
Position
3:complement(161617405..161717759)
Genome browser
AA seq
1130 aa
AA seq
DB search
MACLTMTEMEGTSTFPIHHNGDIPGIVDSVKQIDPVLQVYLYHSLGKAEGDNLKFPTGEY
VAEEICVAASKACGITPVYHSMFALMSETERIWYPPNHIFHIDESTRHSVLYRIRFYFPY
WYCNGSNRTYRHGISRGAEAPLLDDFVMSYLFAQWRHDFLHGWIKVPVTHETQEECLGMA
VLDMMRIAKEKDQTPLDIYNSISYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIEQFSH
CKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSRGK
HKESETLTEQDLQLYCDFPDIIDVSIKQANQEVSNESRIVTIHKQDGKNLEIELSSLREA
LSFVSLIDGYYRLTADAHHYLCKEVAPPMVLENIQSNCHGPISMDFAISKLKRAGNQTGL
YVLRCSPKEFNKYFLTFAVERENVIEYKHCLITKNESGEYNLSGTKKNFNNLKDLLNCYQ
METVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRHNNVNQMVFHKIRN
EDLIFNESLGQGTFTKIFKGIRREIGDFGQLHETEVLLKVLDKAHRNYSESFFEAASMMS
QLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKTSINILWKLEVAKQLAWAMH
FLEEKTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPE
CIENPKSLNLATDKWSFGTTLWEICSGGDKPLNALDSQRKLQFYEDRHQLPAPKWTELAN
LINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDPT
QFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEIL
KSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTFQICK
GMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYA
PESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELL
KNNGRLPRPDGCPDEIYVIMTECWNNNVNQRPSFRHLALRVDQIRDNMAG
NT seq
3393 nt
NT seq
+upstream
nt +downstream
nt
atggcttgccttacaatgacagaaatggaaggaacatccacatttcctatacatcataat
ggtgatattcctggaattgttgattctgtgaagcaaatagatccagtcctacaggtgtat
ctttatcattcccttgggaaagctgagggagataacctgaagtttccaactggggagtat
gttgcagaagaaatttgtgttgctgcttctaaagcctgcggaatcacaccagtgtatcat
agtatgtttgccttaatgagtgaaacagaaaggatctggtatccacccaaccacatcttc
catatagatgagtcaacaaggcacagtgttctctacagaataagattttactttccttac
tggtattgtaatggcagcaatagaacctatcggcatggtatatctcgaggtgctgaagct
cctcttcttgatgactttgtcatgtcttacctttttgctcagtggcgtcatgattttttg
catggatggataaaagtacctgtgactcatgaaacacaggaagaatgtcttgggatggca
gtgttagatatgatgagaatagccaaagaaaaggatcaaaccccacttgacatctataac
tctatcagctacaagacattcttaccaaaatgtgtgcgagcaaagatccaagactatcat
attttgacaagaaagcgaataaggtacagatttcgcagatttattgagcaattcagccat
tgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaactcttcag
tctgcattctacacagaacaatttgaagtaaaagaacctggaagaggtccttcaggtgag
gagatttttgcaaccattataataactggaaacggtggaattcagtggtcaagagggaaa
cataaagaaagtgagacactgacagaacaggatttacagttatattgtgattttcctgat
attattgatgtcagtattaagcaggcaaaccaagaagtctcaaatgaaagcagaattgta
actatccataagcaagatggtaaaaatctggaaattgaacttagctcattaagggaagct
ttgtcctttgtgtcattaattgatggatattatagattaactgcagatgcacatcattac
ctctgtaaagaagtggcacctccaatggtgcttgaaaatatacaaagcaactgtcatggt
ccaatttcgatggattttgccataagtaaactgaagagagcaggtaatcagactggactc
tatgtacttcgatgcagtcctaaggagtttaataaatattttttgacttttgctgtcgag
cgagaaaatgtcattgaatataagcactgtttgattacaaaaaatgagagtggagaatac
aacctcagtgggactaagaagaactttaataatcttaaagatcttttgaactgctatcag
atggaaactgttcgctcagacaatataattttccagtttacaaaatgctgtcccccaaag
ccaaaagataaatctaacctcctggtctttagaaccaatggtgtttctgatgtaccaacc
tcaccaacactacagaggcataataatgtgaaccaaatggtgtttcacaaaatcagaaat
gaagatttgatatttaatgaaagccttgggcaaggcacttttacaaaaatttttaaaggt
ataagaagagaaataggagactttggtcaactgcatgagacagaagttcttttaaaagtt
ttggataaagcacatagaaactattcagagtctttctttgaagcagcaagcatgatgagc
cagctttctcacaagcatctggttttaaattatggagtatgtgtctgtggagaggagaat
attctggttcaggagtttgtgaaatttggatcactagatacatatttaaaaaagaataaa
acttctataaatatattatggaaacttgaagtggctaaacagctggcatgggccatgcat
tttctagaagaaaaaacccttattcatgggaatgtgtgtgccaaaaatattctgcttatc
agagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgaccctggcatt
agtattacagttttgccaaaggacattcttcaggagagaataccgtgggtaccgcctgaa
tgcattgaaaatcctaaaagtttaaacttggcaacagacaagtggagttttggtaccact
ttgtgggaaatctgcagtggaggagataagcctctgaatgctttggattctcagagaaag
ctacagttttatgaagatagacaccagcttcctgcaccaaaatggacagagttagcaaat
cttattaataattgtatggattatgaaccagattttagaccttccttcagagccatcata
cgagatctaaacagtttgtttactcctgattatgaactattaacagagaatgacatgtta
ccaaatatgaggataggtgccctagggttttctggtgcttttgaagaccgagaccctact
cagtttgaagagagacacttgaaatttctgcagcaacttggcaagggtaattttgggagt
gtggagatgtgccggtatgaccctctacaggacaacactggggaggtggtggctgtgaag
aagcttcagcacagcactgaagagcacctcagggactttgaaagggaaattgaaatcctt
aaatccctgcaacatgacaacattgtaaagtacaagggagtgtgctacagtgctggccgg
cgtaatttaagattaattatggaatatttaccatatggaagtttacgtgactatctccag
aagcataaagaacggatagatcataaaaaacttctgcagtacacatttcaaatatgcaag
ggtatggagtatcttggtacaaaaaggtatatccacagggatctggcaacaaggaacata
ttggtggagaatgaaaacagagttaaaattggagattttggattaaccaaagtcttgcca
caagacaaagaatactacaaagtgaaagaacctggtgaaagtcccatattctggtatgct
ccagaatcactgacagagagcaagttttctgtggcctcagatgtttggagctttggagtg
gttctatatgaacttttcacatacattgagaagagtaaaagtccaccagcggaattcatg
cgtatgattggcaatgacaaacaaggacagatgattgtgtttcatttgatagagctcttg
aagaataatggaaggttacctagaccagatggatgcccagatgagatttatgtgatcatg
acagaatgctggaacaataatgtaaatcaacgcccctctttcagacacctcgctcttcga
gttgatcaaataagggacaatatggctggatga
DBGET
integrated database retrieval system
