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Pipistrellus kuhlii (Kuhl's pipistrelle): 118716550
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Entry
118716550 CDS
T07682
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2 isoform X1
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
pkl
Pipistrellus kuhlii (Kuhl's pipistrelle)
Pathway
pkl01521
EGFR tyrosine kinase inhibitor resistance
pkl04062
Chemokine signaling pathway
pkl04148
Efferocytosis
pkl04151
PI3K-Akt signaling pathway
pkl04217
Necroptosis
pkl04550
Signaling pathways regulating pluripotency of stem cells
pkl04630
JAK-STAT signaling pathway
pkl04658
Th1 and Th2 cell differentiation
pkl04659
Th17 cell differentiation
pkl04725
Cholinergic synapse
pkl04917
Prolactin signaling pathway
pkl04920
Adipocytokine signaling pathway
pkl04933
AGE-RAGE signaling pathway in diabetic complications
pkl04935
Growth hormone synthesis, secretion and action
pkl05140
Leishmaniasis
pkl05145
Toxoplasmosis
pkl05152
Tuberculosis
pkl05161
Hepatitis B
pkl05164
Influenza A
pkl05167
Kaposi sarcoma-associated herpesvirus infection
pkl05168
Herpes simplex virus 1 infection
pkl05200
Pathways in cancer
pkl05207
Chemical carcinogenesis - receptor activation
pkl05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
pkl05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pkl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
118716550 (JAK2)
04151 PI3K-Akt signaling pathway
118716550 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
118716550 (JAK2)
09143 Cell growth and death
04217 Necroptosis
118716550 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
118716550 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
118716550 (JAK2)
04659 Th17 cell differentiation
118716550 (JAK2)
04062 Chemokine signaling pathway
118716550 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
118716550 (JAK2)
04917 Prolactin signaling pathway
118716550 (JAK2)
04935 Growth hormone synthesis, secretion and action
118716550 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
118716550 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
118716550 (JAK2)
05207 Chemical carcinogenesis - receptor activation
118716550 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
118716550 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
118716550 (JAK2)
05164 Influenza A
118716550 (JAK2)
05168 Herpes simplex virus 1 infection
118716550 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
118716550 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
118716550 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
118716550 (JAK2)
05140 Leishmaniasis
118716550 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
118716550 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
118716550 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
118716550 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pkl01001
]
118716550 (JAK2)
Enzymes [BR:
pkl01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
118716550 (JAK2)
Protein kinases [BR:
pkl01001
]
Non-receptor tyrosine kinases
JAK family [OT]
118716550 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
Kdo
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
118716550
NCBI-ProteinID:
XP_036289862
LinkDB
All DBs
Position
Unknown
AA seq
1199 aa
AA seq
DB search
MLGPEPVPAPGASQTVAGRRRPVSEAGKGTRCELFSFCRTRGPSSPPRQGKCPEKDCVEM
ACLTMTEMEGTCTPPMHQNGDIPGITDPVKQIDPILQVYLYHSLGKTEGDYLKFSTGEYV
AEEICVAASKACGITPVYHSMFALMNETERIWYPPNHVFHIDESTRHNVLYRIRFYFPYW
YCSGSNRTYRHGITRGAEAPLLDDFVMSYLFAQWRHDFLHGWIKVPVTHETQEECLGMAV
LDMMRIAKENDQTPLDVYSSISYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIEQFSHC
KATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIIVTGNGGIQWSRGKH
KESETLTEQDLQLYCDFPDIIDVSIKQASQEGSNESRIVTIHKQDGKNLEIELSSLKEAL
SFVSLIDGYYRLTADAHHYLCKEVASPVVLENLQSNCHGPISMDFAISKLKKAGNQTGLY
VLRCSPKEFNKYFLTFAVERDNVIEYKHCLITKNENGEFNLSGTKKNFSNLKDLLNCYQM
ETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNSVSDVPTSPTLQRHNNVNQMVFHKIRNE
DLIFNESLGQGTFTKIFKGVRREIGDYGQLHETEVLLKVLDKTHRNYSESFFEAASMMSQ
LSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKSSINILWKLEVAKQLAWAMHF
LEEKNLIHGNVCAKNILLIREEDRKAGNPPFIKLSDPGISVTVLPKDILQERIPWVPPEC
IENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTELANL
INNCMDYEPDFRPSFRAIIRDLNSLFTPAYGIIAFISADYEILLENDMLPNMRIGALGFS
GAFEDQDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLR
DFEREIEILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKL
LQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEP
GESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQM
IVFHLIELLKNNGRLPRPDGCPDEIYLIMTECWNNNVNQRPSFRQLALRVDQIRDNIAG
NT seq
3600 nt
NT seq
+upstream
nt +downstream
nt
atgctcggacccgaacccgtgcccgctccgggggcttcgcagaccgtggccggccggagg
cgcccggtttcagaagcgggtaagggaacaagatgtgaactgttttccttctgcagaaca
agaggcccttcctcccctccgcgccaaggcaaatgtcctgaaaaagactgcgtggaaatg
gcttgcctcacaatgacagaaatggaaggaacatgcacacctcctatgcatcagaatggt
gatattcctggaattactgatcctgtgaaacaaatagatccaatccttcaggtgtatctt
tatcattcccttgggaaaactgagggagattacctgaagttttcaactggggaatatgtt
gcagaagaaatttgtgttgctgcttctaaagcctgtggaatcacacctgtgtatcatagt
atgtttgctttaatgaatgaaacggaaaggatctggtatccacccaaccatgtcttccat
atagatgagtcaactaggcacaatgtactctacagaataagattttactttccttactgg
tattgtagcggcagcaacagaacttatcgacatggaataactcgaggtgctgaagctcct
ctccttgatgactttgttatgtcttacctttttgctcagtggcggcatgattttttgcat
gggtggataaaagtacctgtgactcatgaaacacaggaagagtgtcttgggatggcagta
ttagatatgatgagaatagccaaagaaaatgatcaaaccccactggacgtctatagctct
atcagctataagacattcttaccaaaatgtattcgagcaaagatccaagactatcatatt
ttgacaagaaagcgaataaggtaccgatttcgcagatttattgagcaattcagccattgc
aaagccactgccagaaacttgaaacttaagtatcttataaatctggaaactcttcagtct
gccttctacacagagcaatttgaagtaaaagaacctggaagaggtccttcaggtgaggag
atttttgcaaccattatagtaactggaaacggtggaattcagtggtcaagagggaaacat
aaagaaagtgaaacactgacagaacaggatttacagttatattgtgactttcccgatatt
attgatgtcagtattaagcaggcaagccaagaaggctcaaatgaaagcagaattgtaact
atccataagcaagatggtaaaaatctggaaattgaacttagttcattaaaggaggctttg
tcttttgtgtcattaattgatggatattatagattaactgcagatgcacatcattacctc
tgtaaagaagtagcatctccagtggttcttgaaaatttacaaagcaactgtcatggccca
atttcaatggattttgccataagtaaactgaagaaagcaggtaatcagactggactttat
gtacttcgatgcagtcctaaggagtttaataaatattttttgacttttgctgttgagcgt
gataatgtcattgaatataagcactgtttgattacaaaaaatgagaatggagaattcaac
ctcagtgggactaagaagaacttcagtaatcttaaagatcttttgaattgctatcagatg
gaaactgttcgctcagacaatataattttccaatttacaaaatgttgtcctccaaagcca
aaagataaatcaaaccttctagtcttcagaacaaatagtgtttctgatgtaccaacctca
ccaacattacagagacataataatgtgaaccaaatggtgtttcacaaaatcagaaatgaa
gatttaatatttaatgaaagtcttggccaaggcacttttacaaaaatttttaaaggtgta
agaagagaaataggagattatggtcaactgcatgaaacagaagttcttttaaaagttctg
gataaaacacacagaaactattcagagtctttctttgaagcagcaagcatgatgagccag
ctttctcacaagcatctggttttaaattatggagtatgtgtctgtggagaggagaatatt
ctggttcaggagtttgtgaaatttggatcactagatacatatttgaaaaagaataaaagt
tctataaatatattatggaaacttgaagtggctaaacaattggcatgggccatgcatttt
ctagaagaaaaaaaccttattcatgggaatgtgtgtgccaaaaacattctacttattaga
gaagaagacaggaaggcaggaaatcctcctttcatcaaacttagtgatcctggcattagt
gttacagttttgccaaaggacattcttcaggagagaataccatgggtaccacctgaatgt
attgaaaatcctaaaaacttaaacttggcaacagacaaatggagttttggtaccactttg
tgggaaatctgcagtggaggagataagcctctcagtgctttggattctcaaagaaagcta
cagttttatgaagatagacaccagcttcctgcaccaaagtggacagaattagcaaatctt
attaataattgtatggattatgaaccagattttagaccttctttcagagccatcatacga
gatcttaatagtttgtttactccggcttatggtataatagcctttatttctgcagattat
gaaatattactagagaatgacatgttaccaaatatgaggataggtgccctagggttttct
ggtgcttttgaagaccaagaccctactcagtttgaagagagacacttgaaatttctgcag
caacttggcaagggtaattttggaagtgtcgagatgtgccggtatgaccctctacaagac
aacactggggaggtggtggctgtgaaaaagctccagcacagtactgaagagcacctcaga
gactttgaaagggaaattgaaatccttaaatccctgcagcatgacaacattgtgaagtac
aagggagtgtgctacagtgctggccggcgtaatctacgattaattatggaatatttacca
tatggaagtttacgagactatctccaaaagcataaagaacgaatagatcataaaaaactt
ttgcaatatacatcacaaatatgcaagggtatggaatatcttggtacaaaaaggtatatc
cacagggatctggcaacaaggaatatattggtagagaatgaaaacagagttaaaattgga
gattttgggttaacaaaagtcttgccacaagacaaagaatactacaaagtgaaagaacct
ggtgaaagtcctatattttggtatgctccagaatcactgacagagagcaagttttctgtg
gcctcagatgtttggagctttggagtagtcctgtatgaactcttcacctatattgagaag
agtaaaagtccaccagcggaattcatgcgtatgattggcaatgacaaacaaggacagatg
attgtgtttcatttgatagaactcttgaagaataatggaagattaccaagaccagatgga
tgccctgatgagatctatttgatcatgacagaatgctggaataataatgtaaatcaacgc
ccctctttcagacaactagctcttcgcgttgatcaaataagggacaacatagctggatga
DBGET
integrated database retrieval system