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Panthera uncia (snow leopard): 125930874
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Entry
125930874 CDS
T08832
Name
(RefSeq) hepatocyte growth factor receptor
KO
K05099
proto-oncogene tyrosine-protein kinase Met [EC:
2.7.10.1
]
Organism
puc
Panthera uncia (snow leopard)
Pathway
puc01521
EGFR tyrosine kinase inhibitor resistance
puc04010
MAPK signaling pathway
puc04014
Ras signaling pathway
puc04015
Rap1 signaling pathway
puc04020
Calcium signaling pathway
puc04151
PI3K-Akt signaling pathway
puc04360
Axon guidance
puc04510
Focal adhesion
puc04520
Adherens junction
puc05100
Bacterial invasion of epithelial cells
puc05144
Malaria
puc05200
Pathways in cancer
puc05202
Transcriptional misregulation in cancer
puc05205
Proteoglycans in cancer
puc05206
MicroRNAs in cancer
puc05208
Chemical carcinogenesis - reactive oxygen species
puc05211
Renal cell carcinoma
puc05218
Melanoma
puc05223
Non-small cell lung cancer
puc05225
Hepatocellular carcinoma
puc05226
Gastric cancer
puc05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
puc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
125930874
04014 Ras signaling pathway
125930874
04015 Rap1 signaling pathway
125930874
04020 Calcium signaling pathway
125930874
04151 PI3K-Akt signaling pathway
125930874
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
125930874
04520 Adherens junction
125930874
09150 Organismal Systems
09158 Development and regeneration
04360 Axon guidance
125930874
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
125930874
05202 Transcriptional misregulation in cancer
125930874
05206 MicroRNAs in cancer
125930874
05205 Proteoglycans in cancer
125930874
05208 Chemical carcinogenesis - reactive oxygen species
125930874
05230 Central carbon metabolism in cancer
125930874
09162 Cancer: specific types
05225 Hepatocellular carcinoma
125930874
05226 Gastric cancer
125930874
05218 Melanoma
125930874
05211 Renal cell carcinoma
125930874
05223 Non-small cell lung cancer
125930874
09171 Infectious disease: bacterial
05100 Bacterial invasion of epithelial cells
125930874
09174 Infectious disease: parasitic
05144 Malaria
125930874
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
125930874
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
puc01001
]
125930874
Enzymes [BR:
puc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
125930874
Protein kinases [BR:
puc01001
]
Receptor tyrosine kinases (RTK)
MET family
125930874
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
TIG
Pkinase
Sema
PSI
Kinase-like
Pkinase_fungal
Linker_histone
Ninjurin
Motif
Other DBs
NCBI-GeneID:
125930874
NCBI-ProteinID:
XP_049498926
LinkDB
All DBs
Position
A2:129764587..129877360
Genome browser
AA seq
1382 aa
AA seq
DB search
MKAPAVLAPGILVLLFTLVQKSYGECREALVKSEMNVNMKYQLPNFTAETPIQNVVLHKH
HIYLGAVNYIYVLNDKDLQKVAEYKTGPVLEHPDCFPCQDCSHKANLSGGVWKDNINMAL
LIDTYYDDQLISCGSVHRGTCQRHVLPPSNTADILSKVHCMYSPQADEESSHCPDCVVSA
LGTKVLISEKGRFINFFVGNTINSSYLTDHSLHSISVRRLKETQDGFKFLTDQSYIDVLP
EFRDSYPIKYIHAFESNRFIYFLTVQRETLDAQTFHTRIIRFCSVDSGLHSYMEMPLECI
LTEKRRKRSTREEVFNILQAAYVSKPGAHLAKQIGANLNDDILYGVFAQSKPDSAEPMNR
SAVCAFPIKYVNEFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEVRSDEYRTE
FTTALQRVDLFMGQFNQVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGSSTPHVNF
RLDSHPVSSEAIVEHPLNQNGYTLVVTGKKITKIPLNGLGCEHFQSCSQCLSAPPFVQCG
WCHDKCVQLEECPSGTWTQEICLPTIYEVFPTSAPLEGGTMLTVCGWDFGFRRNNKFDLK
KTRVFLGNESCTLTLSESTTNMLKCTVGPAVNEHFNISIIISNGRGTAQYSTFSYVDPVI
TSIFPSYGPKTGGTLLTLTGKYLNSGNSRHISIGGKTCTLKSVSDSILECYTPAQTIPTE
FPIKLKIDLANREMNSFSYQEDPIVYAIHPTKSFISGGSTITAVGKNLNSVSVLRMVISV
HETRRNFTVACHHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGIHSKYFDLIYVHNP
VFKPFEKPVMISIGNENVLEIKGNDIDPEAVKGEVLKVGNKSCETIYSDSEAVLCKVPND
LLKLNNELNIEWKQAVSSTILGKVIVQPDQNFTGLIVGVISISIILLLLLGVFLWLKKRK
QIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNG
SCRQVQYPLTDLSPMLNSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVH
FNEVIGRGHFGCVYHGTLLDSDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV
LSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKK
FVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQK
FTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKC
WHPKAELRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSQDNIDGEG
DT
NT seq
4149 nt
NT seq
+upstream
nt +downstream
nt
atgaaggcccctgctgtgcttgcacctggcatccttgtgcttctgtttaccttggtgcag
aagagctatggggagtgcagagaggcactagtaaagtctgagatgaatgtgaacatgaag
tatcagcttcccaacttcactgcagaaacacccatccagaatgttgttttacacaagcat
catatttaccttggtgcagttaactatatttacgttttaaatgacaaagaccttcagaag
gttgctgagtacaagactgggcccgtgctggaacacccagattgtttcccatgtcaggac
tgcagccacaaagccaatttatcaggtggtgtttggaaagataacatcaacatggctcta
cttattgacacgtactatgacgaccaactcattagctgtggcagtgtccacagagggacc
tgccagcgacatgtccttccacccagcaatactgctgacatactgtcaaaagttcattgc
atgtactccccacaggcagacgaagagtccagccactgtcctgactgtgtggtgagtgcc
ctgggaaccaaagtcctgatatctgaaaagggccggttcatcaacttcttcgtgggcaat
accataaattcctcttacctaacagatcattcattgcattcaatatcagtgagaaggcta
aaggaaactcaagatggctttaagtttttaacagaccagtcttatattgatgttctccct
gaattcagagattcctaccctattaaatacatccatgcctttgaaagcaaccgttttatt
tactttttgacagtccagcgagaaactctagatgctcagacttttcacacaagaataatc
aggttctgttctgtagactctggattgcattcctacatggaaatgcctctggaatgtatc
ctcacagaaaagagaagaaagagatccacaagggaggaagtgtttaatattctccaagct
gcatatgtcagtaagcctggggcccaccttgctaagcaaataggtgccaacctgaatgat
gacattctctatggagtattcgcacaaagcaagccggattctgctgaaccaatgaatcgc
tctgctgtctgtgcattccctatcaaatatgtcaatgaattcttcaacaagattgtaaac
aaaaacaacgtgagatgtcttcaacatttttatggacccaaccacgaacactgctttaat
aggacacttttgagaaattcatcaggctgtgaagtgcgcagtgatgaatatcgaacggag
tttaccacagctttgcagcgagttgacttattcatgggccaattcaaccaagtcctctta
acatctatatccaccttcattaaaggagacctcaccattgctaatcttgggacgtcagag
ggtcgctttatgcaggttgtggtttctcgatcaggatcatcaacccctcatgtgaatttt
cgcctggattcccaccctgtgtcttcagaagcaattgtggagcacccattaaaccaaaat
ggctacacactggttgttactggaaagaagatcaccaagatcccactgaatggcttaggc
tgtgaacatttccagtcctgcagtcagtgtctttctgcccctccctttgtgcaatgtggc
tggtgccacgataaatgtgtgcaactggaggaatgccccagtggaacatggactcaagag
atctgtctgcctacaatctatgaggttttcccaaccagtgcacccctggaaggaggaaca
atgctcactgtgtgtggctgggactttggattcaggaggaataataaatttgatttaaag
aaaactagagttttccttggaaatgagagctgcactttgaccttaagtgagagcacaaca
aatatgttgaaatgcacagttggtcctgcagtgaatgagcatttcaatatatccataatt
atttcaaatgggcgagggacagcacaatacagtacattttcctatgtggatcctgtaata
acaagtatttttccaagttatggtcctaagaccggtggcaccttgcttactttaactgga
aagtaccttaacagtgggaattctagacacatttcaattggtggaaaaacgtgtacttta
aaaagtgtgtcagatagtattctcgaatgttataccccagctcaaaccattccaactgag
tttcctattaaattgaaaattgacttagccaaccgagagatgaacagtttcagttaccag
gaagaccccattgtctatgcaattcatccaaccaaatcttttattagtggtgggagcacc
ataacagctgttgggaaaaacctgaattcagttagtgtcctaaggatggtaataagtgta
catgaaacaagaaggaactttacagtggcatgtcaccatcgctctaattcagagataatc
tgctgtacaactccttcactgcaacagctgaatctgcaactccctctgaaaaccaaagcc
tttttcatgttagatgggatccattccaaatactttgatctcatttatgtacataatcct
gtgtttaagccttttgaaaagccagtgatgatctcaataggcaatgaaaatgtactggaa
attaagggaaatgatattgaccctgaagcagttaaaggtgaagtgttaaaagttggaaat
aagagctgtgagactatatactcagattctgaagctgttttatgcaaggtccccaatgac
ctgctgaaattgaacaacgagctaaatatagagtggaagcaagcagtttcttcaaccatc
cttggaaaagtaatagttcaaccagatcagaatttcacaggattgattgttggtgttatc
tcaatatcaataatactcttactattacttggggttttcctgtggctgaaaaagagaaag
caaattaaagatctgggcagtgaattagttcgctatgatgcaagagtacacactcctcat
ttggataggcttgtaagtgcccgaagtgtaagcccaactacagaaatggtttcaaatgaa
tctgtagactaccgagctacttttccagaagaccagtttcctaactcatctcagaatgga
tcgtgcagacaagtacagtatcctctgacggacctgtcccccatgcttaatagtggggac
tctgatatatccagtccattactgcaaaatactgtccacattgacctcagtgctctaaat
ccagagctggtccaggcagtccagcacgtagtgattgggccaagtagtctgattgtgcat
ttcaatgaagtcataggaagaggacattttgggtgtgtgtaccatgggactttattggac
agcgatgacaagaagattcactgtgctgtgaaatccttgaatagaatcactgacataggt
gaagtttcccagtttctgactgagggaatcatcatgaaagattttagtcatccaaatgtt
ctctcactcttgggaatctgccttcgaagtgaggggtctccactggtggtcctaccatat
atgaaacatggagatcttcgaaatttcatcagaaatgagactcataacccaactgtaaaa
gatcttattggctttggtcttcaagtagccaaaggcatgaaatatcttgcaagcaaaaag
tttgtacacagagacttggctgctagaaactgtatgctggatgaaaaattcactgtcaag
gttgctgattttggtctggccagagacatgtatgataaagagtactacagtgtacacaac
aaaacgggcgccaagctgccagtgaagtggatggctctagaaagtctacaaactcagaag
tttaccaccaagtcagatgtgtggtcctttggtgtgctcctctgggaactgatgacaaga
ggggctccaccttatcctgatgtcaacacctttgatataacagtttacttattgcaaggc
agaagactcttacagcccgaatactgcccagatcccttatatgaagtgatgctaaaatgc
tggcaccctaaagccgaactgcgcccatctttttctgaactggtctccaggatatcagcg
atattctctactttcattggggagcattatgtccatgtgaacgctacttatgtgaatgtc
aaatgtgttgctccatacccttctctgttgtcatcacaagataacattgatggcgagggg
gacacatga
DBGET
integrated database retrieval system