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Pteropus vampyrus (large flying fox): 105303192
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Entry
105303192 CDS
T07815
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
pvp
Pteropus vampyrus (large flying fox)
Pathway
pvp01521
EGFR tyrosine kinase inhibitor resistance
pvp04062
Chemokine signaling pathway
pvp04148
Efferocytosis
pvp04151
PI3K-Akt signaling pathway
pvp04217
Necroptosis
pvp04550
Signaling pathways regulating pluripotency of stem cells
pvp04630
JAK-STAT signaling pathway
pvp04658
Th1 and Th2 cell differentiation
pvp04659
Th17 cell differentiation
pvp04725
Cholinergic synapse
pvp04917
Prolactin signaling pathway
pvp04920
Adipocytokine signaling pathway
pvp04933
AGE-RAGE signaling pathway in diabetic complications
pvp04935
Growth hormone synthesis, secretion and action
pvp05140
Leishmaniasis
pvp05145
Toxoplasmosis
pvp05152
Tuberculosis
pvp05161
Hepatitis B
pvp05164
Influenza A
pvp05167
Kaposi sarcoma-associated herpesvirus infection
pvp05168
Herpes simplex virus 1 infection
pvp05200
Pathways in cancer
pvp05207
Chemical carcinogenesis - receptor activation
pvp05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
pvp05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pvp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
105303192 (JAK2)
04151 PI3K-Akt signaling pathway
105303192 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
105303192 (JAK2)
09143 Cell growth and death
04217 Necroptosis
105303192 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
105303192 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
105303192 (JAK2)
04659 Th17 cell differentiation
105303192 (JAK2)
04062 Chemokine signaling pathway
105303192 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
105303192 (JAK2)
04917 Prolactin signaling pathway
105303192 (JAK2)
04935 Growth hormone synthesis, secretion and action
105303192 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
105303192 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
105303192 (JAK2)
05207 Chemical carcinogenesis - receptor activation
105303192 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
105303192 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
105303192 (JAK2)
05164 Influenza A
105303192 (JAK2)
05168 Herpes simplex virus 1 infection
105303192 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
105303192 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
105303192 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
105303192 (JAK2)
05140 Leishmaniasis
105303192 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
105303192 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
105303192 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
105303192 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pvp01001
]
105303192 (JAK2)
Enzymes [BR:
pvp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
105303192 (JAK2)
Protein kinases [BR:
pvp01001
]
Non-receptor tyrosine kinases
JAK family [OT]
105303192 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2_1
FERM_F2
Jak1_Phl
ABC1
FERM_C_FAK1
Kinase-like
RIO1
Motif
Other DBs
NCBI-GeneID:
105303192
NCBI-ProteinID:
XP_023377030
UniProt:
A0A6P6BPS1
LinkDB
All DBs
Position
Unknown
AA seq
952 aa
AA seq
DB search
MAVLDMMRIAKEKDQTPLDIYSSVSYKTFLPKCVRAKIQEYHILTRKRIRYRFRRFIEQF
SHCKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSR
GKRKESETLTEQDLQLYCDFPDIIDVSIKQANQEVSNESRIVTIHKQDGKNLEVELNSLR
EALSFVSLIDGYYRLTADAHHYLCKEVAPPTVLENIQSNCHGPISMDFAISKLKKAGNQT
GLYVLRCNPKDFNKYFLTFAVERENVIEYKHCLITKNENGEYNLNGTKKNFSNLKDLLNC
YQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGISDVPTSPTLLRHNNVNQMVFHKI
RNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM
MSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLEVAKQLAWA
MHFLEEKTLFHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVP
PECIENPKSLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTEL
ANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRD
PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE
ILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQI
CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFW
YAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIE
LLKNNGRLPRPDGCPDEIYVIMTECWNNNVNQRPSFRHLALRVDQIRDSMAG
NT seq
2859 nt
NT seq
+upstream
nt +downstream
nt
atggcagtgttagatatgatgagaatagctaaagaaaaggatcaaaccccactggacatc
tatagttctgtcagctacaagacatttttaccaaaatgtgttcgagcaaagatccaagaa
tatcatattttgacaaggaaaagaataagatacagatttcgcagatttattgagcaattc
agccattgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaact
cttcagtctgccttctacacagagcaatttgaagtaaaagaacctggaagaggtccttca
ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga
gggaaacgtaaagaaagtgagacactgacagaacaggatttacagttatattgtgatttt
cctgatattattgatgtcagtattaagcaggcaaaccaggaagtctcaaatgaaagcaga
attgtcactatccataagcaagatggtaaaaatctggaagttgaacttaactcattaaga
gaagctttgtcttttgtgtcattaattgatggatattatagattaactgcagatgcacat
cattacctctgtaaagaagtagcgcctccaacggtgcttgaaaatatacaaagcaactgt
catggcccaatttcaatggattttgccatcagtaaactgaagaaagcaggtaatcagact
ggactctatgtacttcgatgcaatcctaaggactttaataaatattttttgacttttgct
gtagagcgagaaaatgtcattgaatataagcattgtttgattacaaaaaatgaaaacgga
gaatacaacctaaacgggactaagaagaacttcagtaatcttaaagatcttttgaattgc
taccagatggaaactgttcgctcagacaatataattttccagtttacgaaatgctgtccc
ccaaagccaaaagataaatcaaaccttctagtctttagaaccaatggtatttctgatgta
ccaacctcaccaacattactgaggcataataatgtgaaccaaatggtttttcacaaaatt
agaaatgaagatttgatattcaatgaaagccttggccaaggcacttttacaaaaattttt
aaaggtgtaagaagagaagttggagactatggtcaactgcatgaaacagaagtcctttta
aaagttctggataaagcacatagaaactattcagagtctttctttgaagcagcaagtatg
atgagccagctttctcacaagcatctggttttaaattatggagtatgtgtctgtggagag
gagaatattctggttcaggagtttgtgaaatttggatcattagacacatatttgaaaaag
aataaaaattctataaatatattatggaaacttgaagtggctaaacagttggcatgggcc
atgcattttctagaagaaaaaaccctttttcatgggaatgtgtgcgccaaaaatattcta
cttatcagagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgatcct
ggcattagtattacagttttgccaaaggacattcttcaagagagaataccatgggtacca
cctgaatgcattgaaaatcctaaaagtctaaacttggcaacagacaaatggagttttggt
accactttgtgggaaatctgcagtggaggagataagcctctcagtgctttggattctcaa
agaaaactacagttttatgaagataggcaccagcttcctgcaccaaagtggacagaatta
gcaaatcttattaataattgtatggattatgaaccagattttagaccttctttcagagcc
attatacgagatcttaatagtttgtttactccagattatgaactattaacagaaaatgac
atgctaccaaatatgaggataggtgccctggggttttctggtgcttttgaagaccgagac
cctacacagtttgaagagagacacttgaaatttctgcagcaactgggcaagggtaatttt
gggagtgtggagatgtgccgctatgaccctctacaagacaacactggggaggtggtggct
gtgaaaaagctccagcacagcactgaagagcacctcagagattttgaaagggaaattgaa
atccttaaatctctacagcatgacaacattgtaaagtacaagggagtgtgctacagtgct
ggccggcgtaacctaagattaattatggaatatttaccatatggaagtttacgagactat
cttcaaaagcataaagaacggatagatcataaaaaacttctgcagtacacatctcaaata
tgcaagggtatggagtatcttggtacgaaaaggtatatccacagggatctggcaacaagg
aatatattggtggagaatgaaaacagagttaaaattggagattttgggttaaccaaagtc
ttgccacaagacaaagaatactataaagtgaaagaacctggtgaaagtcccatattctgg
tatgctccagaatcactgacagagagcaagttttctgtggcctcagatgtttggagtttt
ggagttgttctttatgaacttttcacatatattgagaagagtaaaagtcctccagcggaa
ttcatgcgtatgattggcaatgacaaacaagggcagatgattgtatttcatttgatagaa
ctcctgaagaataatggaagattaccaagaccagatggatgcccagatgagatttatgta
atcatgacagaatgctggaacaataatgtaaatcaacgcccctctttcagacacctcgct
cttcgagttgatcaaataagggacagcatggctggataa
DBGET
integrated database retrieval system