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Rhinolophus ferrumequinum (greater horseshoe bat): 117031937
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Entry
117031937 CDS
T07722
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
rfq
Rhinolophus ferrumequinum (greater horseshoe bat)
Pathway
rfq01521
EGFR tyrosine kinase inhibitor resistance
rfq04062
Chemokine signaling pathway
rfq04148
Efferocytosis
rfq04151
PI3K-Akt signaling pathway
rfq04217
Necroptosis
rfq04550
Signaling pathways regulating pluripotency of stem cells
rfq04630
JAK-STAT signaling pathway
rfq04658
Th1 and Th2 cell differentiation
rfq04659
Th17 cell differentiation
rfq04725
Cholinergic synapse
rfq04917
Prolactin signaling pathway
rfq04920
Adipocytokine signaling pathway
rfq04933
AGE-RAGE signaling pathway in diabetic complications
rfq04935
Growth hormone synthesis, secretion and action
rfq05140
Leishmaniasis
rfq05145
Toxoplasmosis
rfq05152
Tuberculosis
rfq05161
Hepatitis B
rfq05164
Influenza A
rfq05167
Kaposi sarcoma-associated herpesvirus infection
rfq05168
Herpes simplex virus 1 infection
rfq05200
Pathways in cancer
rfq05207
Chemical carcinogenesis - receptor activation
rfq05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
rfq05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
rfq00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
117031937 (JAK2)
04151 PI3K-Akt signaling pathway
117031937 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
117031937 (JAK2)
09143 Cell growth and death
04217 Necroptosis
117031937 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
117031937 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
117031937 (JAK2)
04659 Th17 cell differentiation
117031937 (JAK2)
04062 Chemokine signaling pathway
117031937 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
117031937 (JAK2)
04917 Prolactin signaling pathway
117031937 (JAK2)
04935 Growth hormone synthesis, secretion and action
117031937 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
117031937 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
117031937 (JAK2)
05207 Chemical carcinogenesis - receptor activation
117031937 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
117031937 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
117031937 (JAK2)
05164 Influenza A
117031937 (JAK2)
05168 Herpes simplex virus 1 infection
117031937 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
117031937 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
117031937 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
117031937 (JAK2)
05140 Leishmaniasis
117031937 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
117031937 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
117031937 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
117031937 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rfq01001
]
117031937 (JAK2)
Enzymes [BR:
rfq01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
117031937 (JAK2)
Protein kinases [BR:
rfq01001
]
Non-receptor tyrosine kinases
JAK family [OT]
117031937 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
117031937
NCBI-ProteinID:
XP_032978835
Ensembl:
ENSRFEG00010014972
LinkDB
All DBs
Position
12:complement(31372929..31472799)
Genome browser
AA seq
1132 aa
AA seq
DB search
MEMACLTMTEMEGTSTSPIHQNGDIPGNDNSVKQIDPILHVHLYHSLGKTEGDYLKFPIG
KYVAEEICVAASKACGITPVYHSMFALMSETERIWYPPNHVFHIDESTRHDVLYRIRFYF
PYWYCNGSNRTYRHGISRGAEAPLLDDFVMSYLFAQWRHDFLHGWIKVPVTHETQEECLG
MAVLDMMRIAKEKDQTPLDIYSSISYKTFLPKCVRAKIQEYHILTRKRIRYRFRRFIEQF
SHCKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGSSGEEIFATIIITGNGGIQWSR
GKHKESETLTEQDLQLYCDFPDIIDVSIKQANQEGSNESRIVTIHKQDGKNLEIELSSLR
EALSFVSLIDGYYRLTADAHHYLCKEVAPPTVLENIQSNCHGPISMDFAISKLRKAGNQS
GLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENGEYNLSGTKKNFNNLKDLLNC
YQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGISDVPTSPTLQRHNNVNQMVFHKI
RSEDLIFNESLGQGTFTKIFKGIRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM
MSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLEVAKQLAWA
MHFLEEKTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVP
PECIENPRNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTEL
ANLINNCMDYEPDFRPSFRAVIRDLNSLFTPDYELLTENDMLPNMRIGVLGFSGAFEDRD
PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE
ILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQI
CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFW
YAPESLTESRFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIE
LLKNNGRLPRPDGCPDEIYVIMTECWNNNVNQRPSFRHLALRVDQIRDNMAG
NT seq
3399 nt
NT seq
+upstream
nt +downstream
nt
atggaaatggcttgccttacaatgacagaaatggaaggaacgtccacatctcctatacat
cagaatggtgatattcctggaaatgataattctgtgaagcaaatagatccgattctgcat
gtgcatctttatcattcccttgggaaaactgagggagattacttgaagtttccaattggg
aagtatgttgcagaagaaatttgtgttgctgcttctaaagcttgtggaatcacacctgtg
tatcatagtatgtttgctttaatgagtgaaacagaaaggatctggtatccgcccaaccat
gtcttccatatagatgaatcaaccaggcacgatgtactctatagaataaggttttacttt
ccttactggtattgtaatggcagcaacagaacctatcggcatggaatatctcgaggtgct
gaagctcctcttcttgatgactttgtcatgtcttacctttttgctcagtggcgtcatgat
tttttgcatgggtggataaaagtacctgtgactcatgaaacacaggaagaatgtcttggg
atggcagtgttagatatgatgagaatagccaaagaaaaggatcaaaccccactggacatc
tacagctctatcagctacaagacattcttaccaaaatgtgttcgtgcaaagatccaagag
tatcatattttgacaaggaagcgaataaggtacagatttcgcagatttattgagcaattc
agccattgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaact
cttcagtctgccttctacacagagcaatttgaagtaaaagaaccgggaagaggttcttca
ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga
gggaaacataaagaaagtgagacactgacagaacaggatttacagttatactgtgatttt
cctgatattattgatgtcagtattaagcaggcaaaccaagaaggctcaaatgaaagcaga
attgtaactattcataagcaagatggtaaaaacctggaaattgaacttagctcattaaga
gaagctttgtcctttgtgtcgttaattgatggatattacagattaactgcagatgcacat
cattacctctgtaaagaagtagcgcctccaacggtgctggaaaatatacaaagcaactgt
catggcccgatttcaatggattttgccatcagtaaactgaggaaagcaggtaatcagagt
ggactctatgtacttcgatgcagtcctaaggactttaataaatattttttgacttttgct
gtcgagcgagaaaatgtcattgaatataagcactgtttgattacaaaaaatgagaatgga
gaatacaacctaagtgggactaaaaagaacttcaataatcttaaagatcttttgaattgc
taccagatggaaactgttcgctcagacaatataattttccagtttacgaaatgctgtccc
ccaaagccaaaagataaatcaaaccttctagtcttcagaaccaatggtatttctgatgtg
cccacctcaccaacattacagaggcataataatgtgaaccaaatggtgtttcacaaaatc
agaagtgaagatttgatatttaatgaaagccttggccaaggcactttcacaaaaattttt
aaaggcataagaagagaagtgggagactatggtcaactgcatgaaacagaagttctttta
aaagttctggataaagcacatagaaactattcagagtctttctttgaagcagcaagcatg
atgagccagctttctcacaagcatctggttttaaattatggagtatgtgtctgtggagag
gagaatattctggttcaggagtttgtgaaatttggatcattagatacatatttgaaaaag
aataaaaattctataaacatattatggaaacttgaagtggctaaacagttggcatgggcc
atgcattttctagaagaaaaaacccttattcatgggaatgtgtgtgccaaaaatattcta
cttatcagagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgatcct
ggcattagtattacagttttgccaaaggacattcttcaggagagaataccatgggtacca
cctgaatgtattgaaaatcctagaaatctaaacttggcaacagacaaatggagtttcggt
accactttgtgggaaatctgcagtggaggagataagcctctgagtgctttggattctcaa
agaaagctacagttttatgaagataggcaccagcttcctgcgccaaagtggacagaatta
gcaaatcttatcaataattgtatggattacgaaccagattttagaccttctttcagagct
gtcatacgagatcttaatagtttgtttactccagattatgaactgttaacagaaaatgac
atgttaccgaatatgaggataggtgtcctcgggttttctggtgcttttgaagaccgagac
cctacacagtttgaagagagacacttgaaatttctgcagcaactgggcaagggtaatttt
gggagtgtggagatgtgccggtatgaccctctacaagacaatactggggaggtggtggct
gtgaaaaagctccagcacagtaccgaagaacacctcagagacttcgaaagggaaattgaa
atccttaaatccctgcagcatgacaacattgtaaagtacaagggagtgtgctacagtgct
ggccggcgcaatctaagattaattatggaatatttaccatatggaagtttacgagactat
ctccaaaagcataaagaacggatagatcataaaaaacttctgcagtacacatctcaaata
tgcaagggtatggaatatcttggtacaaaaaggtatatccacagggatctggcaacaagg
aatatattggtggagaatgaaaacagagttaaaattggagattttgggctaaccaaagta
ttgccacaagacaaagaatactacaaagtgaaagaacctggtgaaagccccatattctgg
tatgctccagaatcactgacagagagcaggttttccgtggcctcagatgtttggagcttt
ggagtggttctgtatgaactttttacatatattgagaagagtaaaagtccaccagcggag
ttcatgcgtatgattggcaatgacaaacaagggcagatgattgtgtttcatttgatagaa
ctcctaaagaataatggaagattaccaagaccagatggatgcccagatgagatttatgtg
atcatgacagaatgctggaacaataatgtaaatcaacgcccctctttcagacacctagct
cttcgagttgatcagataagggacaatatggctggatga
DBGET
integrated database retrieval system
